Associations among body composition, inflammatory profile and disease extent in ulcerative colitis patients

Abstract

Objective: The aim of our study was to assess body composition status and its association with inflammatory profile and extent of intestinal damage in ulcerative colitis patients during clinical remission. Method: This is a cross-sectional study in which body composition data (phase angle [PhA] Lean mass was inversely correlated with non-specific inflammation marker (APMt vs. ESR) and directly correlated with hemoglobin values (MAMC vs. hemoglobin). Logistic regression analysis revealed that body cell mass was associated with disease extent (OR 0.92; 95CI 0.87-0.97; p<0.01). Conclusion: PhA was inversely correlated with inflammatory markers and directly correlated with lean mass. Acute inflammatory markers were correlated with disease extent. Body cell mass was associated with disease extent.

Genome-Wide Regulation of Acupuncture and Moxibustion on Ulcerative Colitis Rats

“…ese results suggested that herb-partitioned moxibustion and electroacupuncture had protective effects on UC rat colon against DSS-induced injury. e CRP level has an obvious correlation with the Mayo score of UC disease and moderate positive correlations with both the clinical classification and endoscopic classification of UC [19,20]. Detection of the serum CRP level can objectively reflect changes in inflammation and disease conditions in UC patients and can be used as an indicator of colonic mucosal repair.…”

The protective effect of nigeglanine on dextran sulfate sodium‐induced experimental colitis in mice and Caco‐2 cells

“…Inflammatory injury underlies UC. Many studies have reported that the inhibition of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), NO and other inflammatory mediators could treat or cure UC (Urbano et al, 2018). The inflammatory mediators regulated inflammatory pathways including nuclear factor kappa B (NF-κB) and mitogenactivated protein kinases (MAPKs; Zhu et al, 2018).…”