Abstract:Background
Breast cancer (BC) is a heterogeneous disease that has different clinical outcomes. Bax-interacting Factor-1 (BIF-1) is a member of the endophilin B family that produces the pro-apoptotic BCL2-Associated X (BAX) protein in response to apoptotic signals. Lack of BIF-1 inhibits the intrinsic pathway of apoptosis and increases the risk of tumor genesis. The aim of the present study was to investigate the relationship between hormone receptors (ER, PR, HER2) status and different levels of BIF-1 gene ex… Show more
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