Association Serum Lipid Levels with Periodontal Disease in Korean Adults Over the Age of 50: The Korea National Health and Nutrition Examination Survey, 2016-2018

Abstract

The prevalence of periodontal disease is 20-50%, and it is a disease that affects about 11.2% of the world' s population [1]. In 2018, the prevalence of periodontal disease in Korea was 23.4% [2], and it took the second place in terms of frequent disease outpatients, with a total cost of 1.345 trillion won [3].Periodontal disease is an inflammatory disease that progressively destroys the tissues surrounding and supporting the teeth, and it is one of the main causes of tooth loss [4]. The causes of periodontal disease include local causes, such as bacterial biofilm, and systemic causes, such as smoking, stress, drugs, diabetes, malnutrition, and immunosuppression [5]. Periodontal disease is revealed as age-related. The prevalence rate of periodontal disease was 5.2% for men and 2.9% for women at the age of 19-29 in Korea, but increases rapidly to 49.7% for men and 32.8% for women at the age of 50-59 [2]. Middle age is a period in which oral diseases are accumulated in earnest, and examining the variables related to periodontal disease in this period will have great meaning in maintain-

Periodontal Disease in Young Adults as a Risk Factor for Subclinical Atherosclerosis: A Clinical, Biochemical and Immunological Study

“…Yeun et al showed in a study of 809 patients with PD, aged >50 years, that HDL alleviated PD, while LDL exacerbated PD. In contrast, total cholesterol and triglycerides were not connected with PD [ 86 ]. However, we found that only triglycerides and LDL correlated with PPD and CAL, whereas LDL, triglycerides, and total cholesterol had a predictive role in atherosclerosis.…”

Investigating the Connection between Chronic Periodontitis and Parkinson’s Disease: Findings from a Korean National Cohort Study

“…Globally, CP is a significant contributor to tooth loss, impacting approximately 11.2% of the population [2]. In Korea, it accounts for 23.4% of periodontal disease cases, ranking second in outpatient visits, with substantial associated costs [3]. CP incidence rises with age, predominantly affecting males, often associated with lower education levels, income, and rural residence [4].…”

“…Studies consistently report poor oral health in PD patients, with a high prevalence of CP [17][18][19], suggesting a potential link between PD and CP due to chronic inflammation and dysbiosis [10,13,20]. Given the widespread occurrence of both CP and PD in Korea [3,21], concerns regarding their comorbidity, especially among elderly individuals with CP, have emerged. CP affects 85.5% of individuals aged 60-69 [3], while PD affects approximately 0.4% of those aged 50 and older [21].…”

“…Given the widespread occurrence of both CP and PD in Korea [3,21], concerns regarding their comorbidity, especially among elderly individuals with CP, have emerged. CP affects 85.5% of individuals aged 60-69 [3], while PD affects approximately 0.4% of those aged 50 and older [21]. Clarifying the potential link between CP and PD holds significant clinical importance [13,22,23], particularly in the absence of preventive measures for PD and considering CP's global prevalence [2].…”

The Association of Chronic Periodontitis as a Potential Risk Factor with Rheumatoid Arthritis: A Nested Case-Control Study Using a Korean National Health Screening Cohort

“…Chronic periodontitis (CP) is a prevalent inflammatory disorder affecting the supportive structures around the teeth, leading to gradual loss of periodontal tissues and underlying bone [9]. It is a significant contributor to tooth loss globally, impacting around 11.2% of the population [10], with an incidence of 23.4% reported in Korea, making it a common reason for outpatient visits [11]. The new classifications of periodontitis released jointly by the European Federation of Periodontology (EFP) and the American Academy of Periodontology (AAP) in 2018 acknowledge the interplay between periodontal diseases and systemic health, highlighting the impact of risk factors like smoking, diabetes, and genetic predisposition on periodontal health [12].…”