Association of Vitamin D–Related Information from a Telephone Interview with 25-Hydroxyvitamin D

Sahota, Harleen; Barnett, Heidi; Lesosky, Maia; Raboud, Janet; Vieth, Reinhold; Knight, Julia A.

doi:10.1158/1055-9965.epi-07-0632

Cited by 29 publications

(37 citation statements)

References 13 publications

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“…Several studies have also correlated outdoor activity with vitamin D status [40-42]. UVB radiation increases vitamin D levels, as it was described earlier.…”

Section: Discussionmentioning

confidence: 94%

Vitamin D status and associated factors in recent-onset type 1 diabetic children in Iran

Ataie‐Jafari

Rahmat

Abbasi

et al. 2012

J Diabetes Metab Disord

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BackgroundIn this study, the prevalence of vitamin D deficiency was assessed in a group of children and adolescent patients with recent-onset type 1 diabetes mellitus (T1DM).MethodsFifty-three patients with age 8–18 years and duration of T1DM less than 8 weeks were recruited. A food frequency questionnaire (FFQ) was used to assess dietary vitamin D and calcium intake. Sunshine exposure was measured using a questionnaire to quantify the amount of time children spent in the sun and other sun-related habits, and a sun index score was generated. Serum 25(OH)D < 20 ng/ml was considered as vitamin D deficiency. Logistic regression was used to assess predictors of vitamin D deficiency.ResultsAll patients were vitamin D deficient (77%) or insufficient (23%). In a logistic regression model, it was shown that the risk of being vitamin D deficient was significantly decreased by sunlight exposure ≥ 15 minutes during the weekends versus < 15 minutes (OR: 0.06, 95% CI: 0.01–0.75; P=0.029). In addition, vitamin D deficiency in boys was lower than girls in this model (OR: 0.164 [95% CI: 0.02–1.11]; P = 0.063).ConclusionVitamin D deficiency is highly prevalent among children and adolescents with T1DM in Iran. Boys and children with ≥ 15 minutes sunlight exposure in weekends were less likely to be vitamin D deficient than girls and those with < 15 minutes sunlight exposure.

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“…Several studies have also correlated outdoor activity with vitamin D status [40-42]. UVB radiation increases vitamin D levels, as it was described earlier.…”

Section: Discussionmentioning

confidence: 94%

Vitamin D status and associated factors in recent-onset type 1 diabetic children in Iran

Ataie‐Jafari

Rahmat

Abbasi

et al. 2012

J Diabetes Metab Disord

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“…In addition, a protective association between UV exposure earlier in life and breast cancer risk, mostly during breast development (23), has been shown, which has led to the hypothesis that vitamin D may be associated with a reduced risk of breast cancer (24). Some studies support this hypothesis, but not all risk estimates are statistically significant (22,(24)(25)(26)(27)(28)(29), both in relation to UV exposure/time spent outdoors (30,31) and vitamin D status (24,32); epidemiologic results are inconsistent (5,33). Moreover, vitamin D status has been inversely associated with breast cancer stage, recurrence, and mortality in some studies (34), but not others (35).…”

Section: Discussionmentioning

confidence: 99%

Vitamin D status and breast cancer in Saudi Arabian women: case-control study

Yousef¹,

Jacobs²,

Kang³

et al. 2013

The American Journal of Clinical Nutrition

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“…Serum 25(OH)D is the major circulating metabolite of vitamin D, reflects input from cutaneous synthesis and dietary intake, and measurement of levels is the standard measure of vitamin D status. The determinants of vitamin D status include exposure to the sun and time spent outdoors[7,8], diet and supplement use[8], latitude, season, age, skin color, and skin coverage (i.e. clothing and sunblock use) [9].…”

Section: Epidemiology Of Vitamin D Deficiencymentioning

confidence: 99%

Childhood asthma may be a consequence of vitamin D deficiency

Litonjua

2009

Current Opinion in Allergy &Amp; Clinical Immunology

158

116

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Purpose of Review Vitamin D deficiency has been rediscovered as a public health problem worldwide. It has been postulated that vitamin D deficiency may explain a portion of the asthma epidemic. The purpose of this review is to present the evidence for a role of vitamin D in asthma. Recent Findings Both animal models and studies in human fetal tissues show that vitamin D plays a role in fetal lung growth and maturation. Epidemiologic studies have also suggested that higher prenatal vitamin D intakes have a protective role against wheezing illnesses in young children. Vitamin D may protect against wheezing illnesses through its role in upregulating antimicrobial proteins or through its multiple immune effects. In addition, vitamin D may play a therapeutic role in steroid resistant asthmatics, and lower vitamin D levels have recently been associated with higher risks for asthma exacerbations. Summary Improving vitamin D status holds promise in primary prevention of asthma, in decreasing exacerbations of disease, and in treating steroid resistance. However, the appropriate level of circulating vitamin D for optimal immune functioning remains unclear. Because vitamin D deficiency is prevalent even in sun-replete areas, clinical trials are needed to definitively answer questions about the role of vitamin D in asthma.

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Association of Vitamin D–Related Information from a Telephone Interview with 25-Hydroxyvitamin D

Cited by 29 publications

References 13 publications

Vitamin D status and associated factors in recent-onset type 1 diabetic children in Iran

Vitamin D status and associated factors in recent-onset type 1 diabetic children in Iran

Vitamin D status and breast cancer in Saudi Arabian women: case-control study

Childhood asthma may be a consequence of vitamin D deficiency

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