volume 10, issue 4, P689-700 2018
DOI: 10.18632/aging.101423
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Jinglu Zhao, Xiaoli Xie, Yuxiao Yao, Qiuming He, Ruizhong Zhang, Huimin Xia, Yan Zhang

Abstract: Hirschsprung disease (HSCR) is a genetic disorder characterized by the absence of neural crest cells in parts of the intestine. This study aims to investigate the association of vesicle-associated membrane protein 5 (VAMP5) and mutated in colorectal cancer (MCC) genetic polymorphisms and their correlated risks with HSCR. We examined the association in four polymorphisms (rs10206961, rs1254900 and rs14242 in VAMP5, rs11241200 in MCC) and HSCR susceptibility in a Southern Chinese population composed of 1473 case…

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