Association of vaccine‐specific regulatory T cells with reduced antibody response to repeated influenza vaccination
Pin‐Hung Lin,
Po‐Ju Hsiao,
Ching‐Fu Pan
et al.
Abstract:Repeated annual influenza vaccinations have been associated with reduced vaccine‐induced antibody responses. This prospective study aimed to explore the role of vaccine antigen‐ specific regulatory T (Treg) cells in antibody response to repeated annual influenza vaccination. We analyzed pre‐ and post‐vaccination hemagglutination inhibition (HI) titers, seroconversion rates, seroprotection rates, vaccine antigen hemagglutinin (HA) ‐specific Treg cells, and conventional T (Tconv) cells. We compared these paramet… Show more
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