Abstract:Background: Persistent pulmonary hypertension of a newborn (PPHN) is a serious condition with a high morbidity and mortality rate, with a complex therapeutic approach. Recently, genetic associations have been found in patients with PPHN, the role of some polymorphisms that explain its pathogenesis has not been well defined. Objective: To determine the frequency of association of SOD2 gene polymorphisms (rs5746136 C>T) in PPHN in the Mexican population. Methods: We included 155 Mexican infants; 76 with PPH… Show more
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