Association of the classification and severity of heart failure with the incidence of contrast-induced acute kidney injury

Xu, Tian; Lin, Maoning; Shen, Xiaohua; Wang, Min; Zhang, Wenjuan; Zhao, Liang; Li, Duanbin; Luan, Yi

doi:10.1038/s41598-021-94910-1

Cited by 12 publications

(10 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Anemia Systematic review and meta-analysis Wei et al (191) Hypotension Systematic review and meta-analysis Ong et al (192) Volume Depletion and Hemodynamic Instability Systematic review and meta-analysis Tea et al (193) NSAID, diuretics and other nephrotoxic drugs Systematic review and meta-analysis Zhang et al (194) ACE-I/ARB usage Randomized trial parallel-group, single-center CAPTAIN trial (195) Acute heart failure NYHA III-IV Multicenter retrospective study Tian et al (196) Hypoalbuminemia Systematic review and meta-analysis Liwei et al (197) Peri-procedural hyperglycemia Systematic review and meta-analysis Jakrin et al (198) Patient…”

Section: Patient-related Risk Factors-modifiable Weight Of Evidence E...mentioning

confidence: 99%

Contrast-induced acute kidney injury and its contemporary prevention

Sůva¹,

Kala²,

Poloczek³

et al. 2022

Front. Cardiovasc. Med.

View full text Add to dashboard Cite

The complexity and application range of interventional and diagnostic procedures using contrast media (CM) have recently increased. This allows more patients to undergo procedures that involve CM administration. However, the intrinsic CM toxicity leads to the risk of contrast-induced acute kidney injury (CI-AKI). At present, effective therapy of CI-AKI is rather limited. Effective prevention of CI-AKI therefore becomes crucially important. This review presents an in-depth discussion of CI-AKI incidence, pathogenesis, risk prediction, current preventive strategies, and novel treatment possibilities. The review also discusses the difference between CI-AKI incidence following intraarterial and intravenous CM administration. Factors contributing to the development of CI-AKI are considered in conjunction with the mechanism of acute kidney damage. The need for ultimate risk estimation and the prediction of CI-AKI is stressed. Possibilities of CI-AKI prevention is evaluated within the spectrum of existing preventive measures aimed at reducing kidney injury. In particular, the review discusses intravenous hydration regimes and pre-treatment with statins and N-acetylcysteine. The review further focuses on emerging alternative imaging technologies, alternative intravascular diagnostic and interventional procedures, and new methods for intravenous hydration guidance; it discusses the applicability of those techniques in complex procedures and their feasibility in current practise. We put emphasis on contemporary interventional cardiology imaging methods, with a brief discussion of CI-AKI in non-vascular and non-cardiologic imaging and interventional studies.

show abstract

Section: Patient-related Risk Factors-modifiable Weight Of Evidence E...mentioning

confidence: 99%

Contrast-induced acute kidney injury and its contemporary prevention

Sůva¹,

Kala²,

Poloczek³

et al. 2022

Front. Cardiovasc. Med.

View full text Add to dashboard Cite

show abstract

“…It has been reported that both procedure- and patient-related risk factors can impact the initiation and progression of CI-AKI, including the volume of contrast agents, pre-existing kidney failure, diabetes, and hemodynamic instability ( Azzalini et al, 2016 ). Our previous studies also proved that the severity of heart failure and the absence of statin application before admission were both independent predictors for CI-AKI ( Lin et al, 2021 ; Xu et al, 2021 ). Considering that CI-AKI can increase the risk of mortality, it is important to identify risk factors for early detection and prevention of the incidence of CI-AKI ( Legnazzi et al, 2020 ).…”

Section: Introductionmentioning

confidence: 63%

Association of Hemoglobin Glycation Index With Contrast-Induced Acute Kidney Injury in Patients Undergoing Coronary Angiography: A Retrospective Study

Chen

Lin

et al. 2022

Front. Physiol.

Self Cite

View full text Add to dashboard Cite

Background: The hemoglobin glycation index (HGI) quantifies interindividual variation in glycation and is positively associated with cardiovascular diseases. However, the association between HGI and contrast-induced acute kidney injury (CI-AKI) remains unclear. Therefore, this study aimed to assess the association of HGI with CI-AKI.Methods: In this observational study, a total of 3,142 patients undergoing coronary angiography (CAG) or percutaneous coronary intervention (PCI) were included. The HGI was calculated as the difference between the measured glycated hemoglobin (HbA1c) and predicted HbA1c. CI-AKI was defined as an increase of either 25% or 0.5 mg/dl (44.2 μmol/L) in the serum creatinine (SCr) level within 72 h following the exposure to contrast medium. Piecewise linear regression analysis was conducted to testify the association of HGI with the proportion of SCr elevation. Modified Poisson’s regression analysis was performed to determine the association between HGI and CI-AKI. Exploratory analysis was also performed according to the stratification of HbA1c levels.Results: Among 3,142 patients, the average age was 66.9 years and 483 of them (15.4%) suffered CI-AKI. Piecewise linear regression analysis demonstrated the linear association of HGI with the proportion of SCr elevation on both positive and negative sides of HGI [HGI <0: β = −9.537, 95% CI (−12.057 to −7.017), p < 0.001; HGI ≥0: β = 1.655, 95% CI (0.125 to 3.186), p = 0.034]. Modified Poisson’s regression analysis showed that the higher absolute value of HGI was strongly associated with higher incidence of CI-AKI [(<−1.0 vs. −0.2 to 0.2): aRR = 1.897, 95% CI [1.467 to 2.452], p < 0.001 (≥1.0 vs. −0.2 to 0.2): aRR = 1.545, 95% CI (1.171 to 2.037), p = 0.002]. Furthermore, the results in exploratory analysis showed that such association still remained irrespective of HbA1c levels.Conclusion: The higher absolute value of HGI was strongly associated with higher incidence of CI-AKI in patients undergoing CAG and PCI.

show abstract

“…The incidence of CI-AKI is reportedly high worldwide and varies from 4.4 to 22.1% according to different definitions (7). Various risk factors, including diabetes, heart failure severity, anemia, renal dysfunction and circulatory insufficiency, have been identified to promote the occurrence of CI-AKI (8)(9)(10). Of the various factors associated with the CI-AKI, inflammation has been demonstrated to be an important risk factor and inflammationbased predictors can effectively determine high-risk CI-AKI (11,12).…”

Section: Introductionmentioning

confidence: 99%

Systemic Immune-Inflammation Index Predicts Contrast-Induced Acute Kidney Injury in Patients Undergoing Coronary Angiography: A Cross-Sectional Study

Jiang

et al. 2022

Front. Med.

Self Cite

View full text Add to dashboard Cite

Background and AimsSystemic immune-inflammation index (SII) is an emerging indicator and correlated to the incidence of cardiovascular diseases. This study aimed to explore the association between SII and contrast-induced acute kidney injury (CI-AKI).MethodsIn this retrospective cross-sectional study, 4,381 subjects undergoing coronary angiography (CAG) were included. SII is defined as neutrophil count × platelet count/lymphocyte count. CI-AKI was determined by the elevation of serum creatinine (Scr). Multivariable linear and logistic regression analysis were used to determine the relationship of SII with Scr and CI-AKI, respectively. Receiver operator characteristic (ROC) analysis, structural equation model analysis, and subgroup analysis were also performed.ResultsOverall, 786 (17.9%) patients suffered CI-AKI after the intravascular contrast administration. The subjects were 67.1 ± 10.8 years wold, with a mean SII of 5.72 × 1011/L. Multivariable linear regression analysis showed that SII linearly increased with the proportion of Scr elevation (β [95% confidence interval, CI] = 0.315 [0.206 to 0.424], P < 0.001). Multivariable logistic regression analysis demonstrated that higher SII was associated with an increased incidence of CI-AKI ([≥12 vs. <3 × 1011/L]: odds ratio, OR [95% CI] = 2.914 [2.121 to 4.003], P < 0.001). Subgroup analysis showed consistent results. ROC analysis identified a good predictive value of SII on CI-AKI (area under the ROC curve [95% CI]: 0.625 [0.602 to 0.647]). The structural equation model verified a more remarkable direct effect of SII (β = 0.102, P < 0.001) on CI-AKI compared to C-reactive protein (β = 0.070, P < 0.001).ConclusionsSII is an independent predictor for CI-AKI in patients undergoing CAG procedures.

show abstract

Association of the classification and severity of heart failure with the incidence of contrast-induced acute kidney injury

Cited by 12 publications

References 35 publications

Contrast-induced acute kidney injury and its contemporary prevention

Contrast-induced acute kidney injury and its contemporary prevention

Association of Hemoglobin Glycation Index With Contrast-Induced Acute Kidney Injury in Patients Undergoing Coronary Angiography: A Retrospective Study

Systemic Immune-Inflammation Index Predicts Contrast-Induced Acute Kidney Injury in Patients Undergoing Coronary Angiography: A Cross-Sectional Study

Contact Info

Product

Resources

About