Association of Social Isolation and Loneliness With Incident Heart Failure in a Population-Based Cohort Study

Liang, Yannis Yan; Chen, Yilin; Feng, Hongliang; Liu, Xiangxin; Ai, Qi Yong H.; Xue, Huachen; Shu, Xinyue; Weng, Foqian; He, Zhixuan; Ma, Jiacheng; Ma, Huan; Ai, Sizhi; Geng, Qingshan

doi:10.1016/j.jchf.2022.11.028

Cited by 30 publications

(26 citation statements)

References 34 publications

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“…In the study by Liang et al, 5 loneliness and social isolation were more common in men and were associated with adverse health behaviors and status, such as tobacco use and obesity. That men are more often socially isolated or lonely is not new information.…”

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confidence: 95%

“…In this issue of JACC: Heart Failure , Liang et al 5 used a large publicly available database from the United Kingdom to examine the relationships between social isolation and/or loneliness among 464,773 participants in the UK Biobank study, a population-based cohort, with the development of heart failure (HF) hospitalization or death over a median of about 12 years. They identified higher rates of HF hospitalization or death with increasing social isolation or with loneliness, although the HRs for both conditions were attenuated by socioeconomic status, health conditions, and medications.…”

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confidence: 99%

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Social Isolation and Loneliness in Heart Failure

Goodlin¹,

Gottlieb

2023

JACC: Heart Failure

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confidence: 95%

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confidence: 99%

Social Isolation and Loneliness in Heart Failure

Goodlin¹,

Gottlieb

2023

JACC: Heart Failure

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“…4 Social isolation, how integrated a person is into their community, and loneliness, the feeling of being alone regardless of the amount of social contact, are related but distinct constructs which are both associated with poor quality of life. 5,6 Importantly, both are modifiable. The goal of this study was to evaluate the association of prefracture social isolation with patient-reported outcomes 1 year after surgical repair of first low-energy hip fracture.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Effect of Social Isolation on 1-Year Outcomes After Surgical Repair of Low Energy Hip Fracture

Mandl,

Rajan,

Lipschultz

et al. 2024

Journal of Orthopaedic Trauma

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OBJECTIVES: To evaluate if social isolation or loneliness is associated with outcomes 1 year after low energy hip fracture. METHODS: Design: Prospective inception cohort study. Setting: Academic Level I Trauma Center. Patient Selection Criteria: Participants were ≥ 65 years of age and enrolled 2-4 days after surgery for a first low energy hip fracture. Exclusion criteria were bilateral or periprosthetic hip fracture, previous hip fracture, non-English speaking, international address, active cancer, stage 4 cancer in the past 5 years, radiation to the hip region and cognitive impairment. Participants were followed longitudinally for one year. Outcome Measures and Comparisons: The PROMIS-29 was elicited 2-4 days post-operatively and 1 year later. Patient reported risk factors included the Lubben Social Networks Scale and the UCLA Loneliness Scale, which were compared to the Lower Extremity Activity Scale and PROMIS-29 domains. RESULTS: Three hundred and twenty-five patients were enrolled. Participants had a median age of 81.7 years, were 70.9 % female and were 85.9% white. 31.6% of patients were socially isolated at time of fracture. At 1 year, 222 of the 291 subjects who were confirmed alive at one year provided data. Multivariable linear models were performed separately for each outcome, including Lower Extremity Activity Scale and PROMIS-29 domains. Controlling for age, sex, education, and body mass index, those who were socially isolated at time of fracture had worse PROMIS-29 function (β= -3.83 p= 0.02) and ability to participate in social roles (β= -4.17 p= 0.01) at 1 year. Secondary analyses found that pre-fracture loneliness was associated with clinically meaningfully worse function, anxiety, depression, fatigue, sleep, pain and ability to participate in social roles at 1 year, (all p< 0.01). CONCLUSIONS: Pre-fracture social isolation was associated with worse outcomes 1 year after surgical repair of low energy hip fracture. This data suggests loneliness may be more strongly associated with important patient centric metrics than pre-fracture social isolation. Given the dearth of modifiable risk factors in this population, future studies are needed to evaluate whether improving social connections could impact outcomes in this rapidly growing demographic.

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“…Feelings of loneliness, which have been linked to negative physical and mental health outcomes such as hypertension, heart failure, stroke, depression, and cognitive impairment, are a risk factor comparable to smoking (Liang et al, 2023; Valtorta et al, 2016; Zhong et al, 2017; Zhong, Chen, et al, 2016). The COVID‐19 pandemic has led to extensive investigation of loneliness in older adults (Ozdemir & Celen, 2023; Su et al, 2023).…”

Section: Introductionmentioning

confidence: 99%

Loneliness in older Chinese adults amid the COVID‐19 pandemic: Prevalence and associated factors

Ruan¹,

Xu²,

Zhong³

2023

Asia-Pacific Psychiatry

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IntroductionData on loneliness among older adults in China during the COVID‐19 pandemic are still scarce. This study aimed to examine the prevalence of loneliness and identify its associated factors among older Chinese adults during the COVID‐19 pandemic.MethodsDuring the COVID‐19 pandemic, 1268 older Chinese adults (aged 50+ years) were recruited through snowball sampling. The Chinese version of the validated six‐item De Jong Gierveld Loneliness Scale was used to assess participants' recent feelings of loneliness, and a cut‐off score of two or more was used to indicate the presence of loneliness.ResultsLoneliness was experienced by 37.9% of the participants in recent days. Factors significantly associated with loneliness included male sex (vs. female, OR: 1.62, p < .001), an education level of middle school and below (vs. college and above, OR: 1.50, p = .007), residing in the COVID‐19 epicenter (vs. other provinces, OR: 1.48, p = .004), concern about contracting COVID‐19 (OR: 1.68, p = .001), poor knowledge of COVID‐19 (OR: 2.39, p = .012), and physical health problems (OR: 1.65, p < .001).DiscussionLoneliness is common among older Chinese adults amid the COVID‐19 pandemic. Targeted intervention programs may be more effective in reducing loneliness among older adults who are worried about contracting COVID‐19, have poor COVID‐19 knowledge, and experience physical health problems.

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Association of Social Isolation and Loneliness With Incident Heart Failure in a Population-Based Cohort Study

Cited by 30 publications

References 34 publications

Social Isolation and Loneliness in Heart Failure

Social Isolation and Loneliness in Heart Failure

The Effect of Social Isolation on 1-Year Outcomes After Surgical Repair of Low Energy Hip Fracture

Loneliness in older Chinese adults amid the COVID‐19 pandemic: Prevalence and associated factors

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