Association of Sleep Duration with Hyperuricemia in Chinese Adults: A Prospective Longitudinal Study

Yu, Huan; Shi, Kexiang; Sun, Dianjianyi; Lv, Jun; Ma, Yanhe; Yin, Sailimai Man Jianchun; Wang, Bo; Yu, Canqing; Li, Liming

doi:10.3390/ijerph19138105

Cited by 2 publications

(2 citation statements)

References 41 publications

(50 reference statements)

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“…The long night flight time could cause more sleep problems in senior pilots since night flights have been linked to circadian rhythm disturbance. The findings Consistent with other findings that short night sleep duration is associated with a higher risk of HUA (30), our data also shows a positive relationship between HUA and sleep disorders, but only among airline pilots aged 30-44 years. Moreover, we could not determine whether high levels of UA lead to sleep disorders in this study.…”

Section: Discussionsupporting

confidence: 93%

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Association of age and night flight duration with sleep disorders among Chinese airline pilots

Shi,

Wang,

et al. 2023

Front. Public Health

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ObjectiveNight flights might aggravate sleep disorders among aging airline pilots, posing a threat to flight safety. In this study, we assess the prevalence of sleep disorders as well as the combined effects of night flight duration and aging on sleep disorders.MethodA cross-sectional study was conducted between July and December, 2021. Participants were recruited from a commercial airline. Sleep disorders were evaluated using the Pittsburgh Sleep Quality Index (PSQI). The interaction effect of night flight duration and age on sleep disorders and their correlates were examined using logistic regression models.ResultsIn total, 1,208 male airline pilots were included in the study, with a median age of 34 (interquartile range [IQR]: 29–39) years. The overall prevalence of sleep disorders was 42.6%. The multivariate logistic regression identified an interaction between night flight duration and age on sleep disorders (adjusted odds ratio [aOR] of the interaction term was 5.85 95% CI: 2.23–15.34 for age ≥ 45 years; 1.96 95% CI:1.01–3.81 for the age group 30–44 years). Longer night flight duration (aOR: 4.55; 95%CI: 1.82–11.38) and body mass index (BMI) ≥28.0 kg/m2 (aOR: 0.16; 95% CI: 0.03–0.91) were significantly associated with sleep disorders in participants aged ≥45 years. Hyperuricemia (aOR: 1.54; 95% CI: 1.09–2.16) and regular exercise (aOR: 0.23; 95% CI: 0.08–0.70) were significantly associated with sleep disorders in the 30–44 years age group.ConclusionThe mean monthly night flight duration and aging had a synergistic effect on airline pilots’ sleep disorders, implying an aging and work-related mechanistic pathogenesis of sleep disorders in airline pilots that requires additional exploration and intervention.

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Section: Discussionsupporting

confidence: 93%

“…Consistent with other findings that short night sleep duration is associated with a higher risk of HUA ( 30 ), our data also shows a positive relationship between HUA and sleep disorders, but only among airline pilots aged 30–44 years. Moreover, we could not determine whether high levels of UA lead to sleep disorders in this study.…”

Section: Discussionsupporting

confidence: 92%

Association of age and night flight duration with sleep disorders among Chinese airline pilots

Shi,

Wang,

et al. 2023

Front. Public Health

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Epidemiological Features of Uterine Fibroid-associated Imaging Changes in Chinese Women of Reproductive Age: Real-World Study (Preprint)

Zhang¹,

Gong²,

Huang³

et al. 2023

Preprint

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BACKGROUND Uterine fibroids (UF), common benign tumors in women of reproductive age, confer substantial costs. The epidemiological characteristics of UF are unclear in China and Asia. OBJECTIVE This study investigated UF-associated imaging changes, and their prevalence, incidence, and risks in the Chinese population. METHODS This population-based retrospective analysis of multiyear (2017–2020) health examination data (n=33,915 female participants; age ≥15 years) from Nanchong, China included two expert consultation rounds to identify entries of UF-associated imaging changes and calculate prevalence and incidence of UF-associated imaging changes. Logistic regression estimated the association (odds ratio [OR], 95% confidence interval [CI]) of body mass index, high blood pressure, blood lipid profile, and fasting blood glucose level with UF-associated imaging changes. Age-stratified (≤40 and >40 years) risks were ascertained. RESULTS Besides “considering UF”, 17 entries of UF-associated imaging changes screened by the expert consultation were included, involving a total of 46,864 records (n=33,915), and crude prevalence=25.18%; crude incidence density/1000-woman-years=63.28. Incidence and prevalence increased with age during reproductive age (15–49 years) and decreased thereafter. The greatest burden was in 40–54 years women, the prevalence is 38.60%–45.38% and the incidence is 14.73%–17.96%. In the incident younger population (age ≤40 years), risk factors (OR [95% CI]) for UF-associated imaging changes were overweight, high blood pressure (1.48 [1.03–2.14] and 2.16 [1.10–4.24], respectively); in the >40 group, no association was observed. CONCLUSIONS UF incidence and prevalence in Asians were higher than previously reported, showed age-related increase in reproductive age, and UF incidence increased with overweight, high blood pressure in ≤40-year-old participants. Variation in UF burden and risk factors was noted in different age range, and risk factors identified in the younger women population make it possible to be early preventive measures for women with a higher risk of UF.

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Association of Sleep Duration with Hyperuricemia in Chinese Adults: A Prospective Longitudinal Study

Cited by 2 publications

References 41 publications

Association of age and night flight duration with sleep disorders among Chinese airline pilots

Association of age and night flight duration with sleep disorders among Chinese airline pilots

Epidemiological Features of Uterine Fibroid-associated Imaging Changes in Chinese Women of Reproductive Age: Real-World Study (Preprint)

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