Association of HLA B‐ and T‐cell molecular mismatches with HLA antibodies, rejection, and graft survival in pediatric kidney transplantation
Ann‐Maria Gramkow,
Johanne H. Baatrup,
Emilie T. Gramkow
et al.
Abstract:BackgroundOptimizing graft survival and diminishing human leukocyte antigen (HLA) sensitization are essential for pediatric kidney transplant recipients. More precise HLA matching predicting epitope mismatches could reduce alloreactivity. We investigated the association of predicted HLA B‐ and T‐cell molecular mismatches with the formation of de novo donor‐specific antibodies, HLA antibodies, rejection, and graft survival.MethodsForty‐nine pediatric kidney transplant recipients transplanted from 2009 to 2020 w… Show more
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