Association of sarcopenia with depressive symptoms and functional status among ambulatory community-dwelling elderly

Kılavuz, Aslı; Meseri, Reci; Savaş, Sumru; Şimşek, Hatice; Şahin, Sevnaz; Bıçaklı, Derya Hopancı; Saraç, Fulden; Uyar, Mehmet; Akçiçek, Fehmi

doi:10.1016/j.archger.2018.03.003

Cited by 24 publications

(36 citation statements)

References 39 publications

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“…Previous studies have shown that there was an important correlation between functional disability and depressive symptoms in the elderly [27][28][29]. Nyunt MS et al found that the improvement in the levels and remission of depressive symptoms were associated with improvement in functional ability among community-living older adults who were treated for depressive symptoms in a primary care setting in Singapore [27].…”

Section: Introductionmentioning

confidence: 99%

“…A study of 1,268 subjects aged 60 and over in Taiwan found that functional disability may contribute to subsequent depressive symptoms by reducing activity and social support [28]. Another study based on 2,713 US Chinese older adults aged 60 and over found that the odds of ADL disability onset (OR = 1.06), IADL disability onset (OR = 1.05), and mobility disability onset (OR = 1.05) among elderly people with depressive symptoms [29].…”

Section: Introductionmentioning

confidence: 99%

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Association between functional disability and depressive symptoms among older adults in rural China: a cross-sectional study

Rong

Wang

et al. 2020

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Background: The association between functional disability and depressive symptoms among elderly people in rural China is not clear. This study explored the relationship between functional disability and depressive symptoms, focusing on whether an interactive association between functional disability, demographic characteristics and depressive symptoms exists among older adults in rural Anhui, China.Methods: A cross-sectional survey study was conducted with multi-stage stratified random sampling. The 30-item Geriatric Depression Scale and WHO Disability Assessment Schedule 2.0 were used to evaluate depressive symptoms and functional disability, respectively. The data were analyzed using SPSS statistics 25.0 program with chi-square test, Mann-Whitney U test, binary logistic regression analysis, and classification and regression tree model.Results: The prevalence of depressive symptoms in 3336 older people was 52.94%. After adjustment, subjects who had problems in participation (adjusted odds ratio [AOR]=3.499, 95% confidence interval [CI]: 2.385-4.987), life activities (AOR=1.683, 95% CI: 1.370-2.066), getting along (AOR=1.616, 95% CI: 1.299-2.010), and mobility (AOR=1.842, 95% CI: 1.503-2.258) had an increased depressive symptoms risk. However, cognition (AOR=0.785, 95% CI: 0.647-0.953) negatively correlated with depressive symptoms. Additionally, the interactive association between functional disability dimensions, various variables and depressive symptoms were identified for the first time. Those who had problems in mobility, getting along and were unemployed, the possibility of having depressive symptoms was the highest.Conclusions: Special attention should be paid to unemployed older adults, and those with problems in participation, life activities, getting along, and mobility and no problems in cognition to maintain a good psychological state. Our findings may be greatly significant for developing more targeted and effective mental health prevention and intervention measures for older adults in rural areas.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Association between functional disability and depressive symptoms among older adults in rural China: a cross-sectional study

Rong

Wang

et al. 2020

Preprint

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“…1), we finally included 14 studies assessing the difference in health care costs between individuals with or without sarcopenia [10][11][12][13][14][15][16][17][18][19][20][21][22][23]. Sixteen studies were rejected because of duplicate (n = 2) [11,20], wrong outcomes (n = 13) [24][25][26][27][28][29][30][31][32][33][34][35][36] or wrong exposure factor (n = 1) [38].…”

Section: Literature Searchmentioning

confidence: 99%

The health economics burden of sarcopenia: a systematic review

et al. 2019

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Despite of better knowledge about sarcopenia, an optimal understanding of its consequences from a public health perspective remains a challenge. Specifically, the economic burden of the illness is unclear. As a support for the public health policy makers and other health actors, our objective was to perform a systematic review of the literature comparing healthcare costs between sarcopenic and non-sarcopenic patients (under the registration number CRD42018099291). A search for relevant articles was conducted on the Medline and Scopus databases. Rigorous eligibility criteria were established (e.g., subjects with sarcopenia, both men and women, mean age of the sarcopenic population) and applied by two investigators to identify suitable studies. The first screening phase, performed by 2 independent reviewers, covered 455 references. Fourteen relevant studies were included in the final analysis. Overall, we noted an important heterogeneity between studies in the way of assessing sarcopenia (i.e. operational definitions, tools and cut-offs used). There were also large variations between studies in their cost analysis settings (i.e., discrepancies in time horizon, types and sources of economic data). Most of the studies focused on hospitalization costs following surgery for a specific disease such as cancer. Finally, 11 out of the 14 studies reported higher healthcare costs for sarcopenic patients. However, most of the included studies have important methodological bias (e.g. potential confusion factors rarely taken into account), and low to moderate quality scores. More standardized research, taking into account all the limitations of the published studies, should be conducted to assess the true impact of sarcopenia on healthcare consumption.

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“…Studies have shown that functional disability was a related factor for depressive symptoms, but most studies were based on the Western population and mainly aimed at revealing the related factors of depressive symptoms among older adults [18,28,29]. However, epidemiological evidence for the association between functional disability and depressive symptoms continue to remain insu cient, especially for the vulnerable group, i.e., the elderly in rural areas in China.…”

Section: Introductionmentioning

confidence: 99%

Association Between Functional Disability and Depressive Symptoms Among Older Adults in Rural China: A Cross-Sectional Study

Rong

Wang

et al. 2020

Preprint

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Abstract Background: The association between functional disability and depressive symptoms among elderly people in rural China is not clear. This study explored the relationship between functional disability and depressive symptoms, focusing on whether an interactive association between functional disability, demographic characteristics and depressive symptoms exists among older adults in rural Anhui, China.Methods: A cross-sectional survey study was conducted with multi-stage stratified random sampling. The 30-item Geriatric Depression Scale and WHO Disability Assessment Schedule 2.0 were used to evaluate depressive symptoms and functional disability, respectively. The data were analyzed using SPSS statistics 25.0 program with chi-square test, Mann-Whitney U test, binary logistic regression analysis, and classification and regression tree model.Results: The prevalence of depressive symptoms in 3336 older people was 52.94%. After adjustment, subjects who had problems in participation (adjusted odds ratio [AOR]=3.499, 95% confidence interval [CI]:2.385-4.987), life activities (AOR=1.683, 95% CI: 1.370-2.066), getting along (AOR=1.616, 95% CI: 1.299-2.010), and mobility (AOR=1.842, 95% CI: 1.503-2.258) had an increased depressive symptoms risk. However, cognition (AOR=0.785, 95% CI: 0.647-0.953) negatively correlated with depressive symptoms. Additionally, the interactive association between functional disability dimensions, various variables and depressive symptoms were identified for the first time. Those who had problems in mobility, getting along and were unemployed, the possibility of having depressive symptoms was the highest.Conclusions: Special attention should be paid to unemployed older adults, and those with problems in participation, life activities, getting along, and mobility and no problems in cognition to maintain a good psychological state. Our findings may be greatly significant for developing more targeted and effective mental health prevention and intervention measures for older adults in rural areas.

show abstract

Association of sarcopenia with depressive symptoms and functional status among ambulatory community-dwelling elderly

Cited by 24 publications

References 39 publications

Association between functional disability and depressive symptoms among older adults in rural China: a cross-sectional study

Association between functional disability and depressive symptoms among older adults in rural China: a cross-sectional study

The health economics burden of sarcopenia: a systematic review

Association Between Functional Disability and Depressive Symptoms Among Older Adults in Rural China: A Cross-Sectional Study

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