Association of renal function with ambulation in mild acute stroke patients

Kubo, Hajime; Nozoe, Masafumi; Kanai, Masashi; Yamamoto, Miho; Kamo, Arisa; Noguchi, Madoka; Mase, Kyoshi; Shimada, Shinichi

doi:10.1080/10749357.2019.1634361

Cited by 2 publications

(1 citation statement)

References 37 publications

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“…We presented the unadjusted model (Model 1), then the model adjusted for age, history of stroke, and height (Model 2). Age and history of stroke were included due to their known associations with walking capacity (19,23,(59)(60)(61)(62)(63)(64) and global cognitive function (18, 65), and height was included to account for the known energy efficiency associated with walking with longer lower limb lengths (energy cost 2.6% lower for each 1 cm longer length) (66). To determine if there were sex-based differences in the association between global cognitive function and walking capacity, we included sex and an interaction term between sex*6 MWT distance in Models 3 and 4.…”

Section: Statistical Analysesmentioning

confidence: 99%

The association between global cognitive function and walking capacity in individuals with broad ranges of cognitive and physical function: Are there sex differences?

Wiley

Noguchi

Moncion

et al. 2022

Front. Rehabilit. Sci.

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IntroductionCognitive function is known to be associated with physical function, where greater walking capacity has been shown to have moderate to strong correlations with global cognitive function and other various domains of cognition in older adults with and without chronic conditions. Biological sex may moderate the relationship between cognitive and physical function, but whether sex differences exist in this association has not been examined in an aging population. The purpose of this study was to examine the associations between global cognitive function (Montreal Cognitive Assessment; MoCA), walking capacity (6-Minute Walk Test distance; 6 MWT) and sex in an aging population with broad ranges of cognitive and physical function.MethodsParticipants were assessed for global cognitive function (MoCA) and walking capacity (6 MWT). Multivariable regression analyses were performed to examine the interaction of sex in the association between MoCA and 6 MWT. First, we presented the unadjusted model (Model 1), then the model adjusted for age, history of stroke, and height (Model 2). To determine if there were sex-based differences in the association between global cognitive function and walking capacity, we included sex and an interaction term between sex*6 MWT distance in Models 3 and 4.ResultsTwenty-three females and 36 males were included in the multivariable regression analyses, respectively. Our sample represented broad ranges of cognitive and physical function levels, where MoCA scores ranged from 13 to 30, and 6 MWT distances from 203 to 750 m. 6 MWT distance was associated with MoCA in models unadjusted (R2 = 0.17; F(1,56) = 11.4; p < 0.01) and adjusted for age, stroke history, and height (R2 = 0.20; F(4,53) = 3.2; p = 0.02). No interaction with sex was found, but a main effect of sex was observed (R2 = 0.26; F(5,21) = 3.72; p = 0.03). When adjusting for age, height and history of stroke, males MoCA scores were 2.9 ± 1.3 less than the mean MoCA scores for females.DiscussionOur findings confirm the positive relationship between cognitive and physical function in older adults. Notably, we also observed superior performance in global cognition among females that was consistent across a broad spectrum of walking capacity.

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Section: Statistical Analysesmentioning

confidence: 99%

The association between global cognitive function and walking capacity in individuals with broad ranges of cognitive and physical function: Are there sex differences?

Wiley

Noguchi

Moncion

et al. 2022

Front. Rehabilit. Sci.

View full text Add to dashboard Cite

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The functional prognosis of older adults in a postacute care center: the impact of dementia

Bermudez,

Salvat,

Viñuelas

et al. 2024

Preprint

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Introduction: The functional recovery of older adults in postacute care units is influenced by demographic and clinical factors, including the presence of dementia. However, studies on this topic are scarce and do not often focus on this population. Objective: The objective was to determine the influence of different factors on the functional prognosis, mortality and need for support at discharge of patients admitted to a postacute care centre, controlling for the presence of dementia. Methods: We conducted a prospective observational study. We analysed the correlations between demographic and clinical factors and functional improvement (according to the Barthel Index, Tinetti test and Functional Ambulation Category scale), the need for support at discharge and mortality. We performed bivariate analysis followed by binary logistic regression or linear regression depending on the type of variable. Results: A total of 206 patients were included. The presence of dementia and delirium were related to most outcome variables, so the sample was stratified according to the presence of dementia. After multivariate analysis, functional outcome of people with dementia was influenced by their previous autonomy and degree of improvement in hospital, the presence of delirium and anaemia on admission, as well as having a hearing deficit. The risk of death was associated with malnutrition, inflammation, antipsychotic treatment and having more functional losses prior to admission. People without dementia had better baseline functioning, influenced by few clear factors, where those with higher education and not married had better prognosis in autonomy and risk of falls and only malnutrition was a risk factor for mortality. Conclusions: Dementia status is a determining factor for functional improvement, autonomy and mortality after admission to a postacute care unit. Differentiated risk algorithms for patients with and without dementia, would allow better targeting of functional rehabilitation.

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Association of renal function with ambulation in mild acute stroke patients

Cited by 2 publications

References 37 publications

The association between global cognitive function and walking capacity in individuals with broad ranges of cognitive and physical function: Are there sex differences?

The association between global cognitive function and walking capacity in individuals with broad ranges of cognitive and physical function: Are there sex differences?

The functional prognosis of older adults in a postacute care center: the impact of dementia

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