Association of quality of life, anxiety, and depression with restless leg syndrome in the hemodialysis patients

Yaseen, Mahjabeen; Jarullah, Furqan Ahmad; Yaqoob, Sadia; Shakeel, Hassan Abdullah; Maqsood, Hamza; Sattar, Naveed

doi:10.1186/s13104-021-05701-w

Cited by 6 publications

(5 citation statements)

References 22 publications

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“…This is in correspondence with the research done in Karachi at the Institute of Kidney Diseases where the prevalence of RLS was 26.7%. 10 Like our results, 26.6% RLS prevalence in ESRD patients was identified in a study conducted in Greece. 11 Giannaki et al also had similar frequency results as ours (27.1%).…”

Section: Discussionsupporting

confidence: 84%

Restless leg syndrome and associated factors in patients with end-stage renal disease on haemodialysis.

Ali¹,

Junejo

Kumar

et al. 2022

TPMJ

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Objective: To assess the frequency and the risk factors associated with restless leg syndrome (RLS) in patients suffering from end-stage renal disease (ESRD) on hemodialysis. Study Design: Cross-sectional Observational study. Setting: Department of Nephrology, Jinnah Postgraduate Medical Centre, Karachi, Pakistan. Period: 1st of January 2020 till 30th of June 2020. Material & Methods: We enrolled the patients in this study after written consent and were assessed for RLS according to the International RLS Study Group criteria. Serum samples were collected for hemoglobulin level, parathyroid hormone level, vitamin D, serum urea and creatinine, and serum ferritin. The sampling technique used was non-probability, variables were recorded as mean and standard deviation and frequency. Results: Ninety-four patients were included in this study; men comprised 65.95% of the patients, and women comprised 34.04%. The mean age in the study was 45.51±13.29 years. Diabetes mellitus was the most common cause (47.87%). The mean duration on the hemodialysis was 5.21 years, and the mean vitamin D level was 24.36 mg/dl. RLS was observed in 26 (27.65%) patients and was significantly associated with low vitamin D and time duration on hemodialysis. Conclusion: The RLS seems to be a common consequence of ESRD, and it has a significant impact on the ESRD patients' everyday lives and sleeping patterns. There is a definitive link between RLS and hemodialysis duration; however, more large multicenter studies are still needed to establish and investigate the etiology.

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Section: Discussionsupporting

confidence: 84%

Restless leg syndrome and associated factors in patients with end-stage renal disease on haemodialysis.

Ali¹,

Junejo

Kumar

et al. 2022

TPMJ

View full text Add to dashboard Cite

show abstract

“…Likewise, a study in Korea on RLS suggests a 12% prevalence [13], which indicates a higher percentage in Asia, defying the percentage designated in the previous study [11]. There are a few studies done in Pakistan to check the prevalence of this disease but all of them are either on Pregnant women [25], diabetics [26], hemodialysis patients [27], or other patients having specific diseases. This research cannot be generalized.…”

Section: Discussionmentioning

confidence: 92%

Incidence of Restless Legs Syndrome in Pakistan and Its Relationship With Depression, Gender, and Age: A Cross-Sectional Study

Zahid,

Ali

2024

Chronobiol Med

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Objective: Restless legs syndrome (RLS) is a neurological disorder known to cause an uncomfortable feeling in the legs, that is alleviated by movement and the symptoms are worse at night or in the evening This study aims to find out the prevalence of restless legs syndrome in Pakistan and to investigate whether it has any association with depression, gender or age.Methods: In this cross-sectional study, a sample size of 377 was calculated using Raosoft. However, 400 participants were included after informed verbal consent, but after 20 dropouts, 380 sample size was finalized. The diagnosis of RLS was done by International Restless Legs Syndrome Study Group (IRLSSG) diagnostic criteria, the diagnosis of depression and its severity was checked by Becks Depression Inventory. A series of tests, namely, descriptive statistics, chi-square test, independent sample t-test, and one-way analysis of variance were calculated via SPSS Software version 27.Results: The prevalence of RLS in Pakistan is 23.7%. There was no difference in depression score with respect to RLS (F=0.270, p=0.604), and there was no difference in severity of depressive symptoms with respect to RLS (p=0.741). There was no difference in gender in prevalence of RLS (χ<sup>2</sup>=1.842, p=0.175). However, there is significant difference in RLS with respect to age (χ<sup>2</sup>=9.598, p=0.048).Conclusion: RLS is quite common in Pakistan with a prevalence of 23.7%. However, the onset of RLS is unrelated to depression and gender, but the prevalence of RLS increases with age. Future studies should focus on investigating severity of RLS and ways to prevent it. It is relation with age can be studied further to help with the prognosis.

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“…Similarly, HCV infection also manifests as both acute and chronic hepatitis C. Most cases develop a chronic infection that leads to cirrhosis, hepatocellular carcinoma, cardiovascular disorders, and neurological manifestation like hepatic encephalopathy [ 12 , 13 ]. Moreover, hemodialysis patients suffer from anxiety and depression, which can be exacerbated by this infection, leading to increased morbidity and mortality [ 14 ].…”

Section: Discussionmentioning

confidence: 99%

Seroprevalence of Hepatitis B Virus and Hepatitis C Virus in Patients Undergoing Maintenance Hemodialysis

Shabbir¹,

Hassan²,

Raza³

et al. 2022

Cureus

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Background Underdeveloped countries suffer a huge burden of infectious diseases, among which hepatitis B virus (HBV) and hepatitis C virus (HCV) are of major concern. Our study sought to determine the seroconversion rate for HBV via hepatitis B antigen (HBsAg) and HCV via anti-hepatitis C virus antibodies (anti-HCV) among patients on maintenance hemodialysis in the dialysis unit of a tertiary care hospital in Pakistan. Methodology This study was carried out from October 2020 to January 2022 at the hemodialysis unit and the urology department of a tertiary care hospital in Multan. A total of 172 patients of both genders were screened for HBV and HCV seropositivity. Data analysis was done through IBM SPSS Statistics for Windows, Version 25.0 (Released 2017; IBM Corp., Armonk, New York, United States). Conclusions were drawn accordingly. Results At the one-year follow-up, screening revealed that 20 (11.7%) patients were positive for HBsAg and 39 (23%) were positive for anti-HCV. Five patients had dual seropositivity for HBsAg and anti-HCV, while three were positive for both HBsAg and anti-HDV. Four out of 20 patients who screened positive for HBsAg and 11 out of 39 patients screened for anti-HCV had a history of one more blood transfusion. Though the correlation between the duration of hemodialysis and viral markers was significant (p<0.05) for the patients screened positive for anti-HCV, a similar correlation was not observed in the patients with seropositivity for HBsAg. Conclusion Our study concludes that seroconversion is statistically significant for HCV infection compared to HBV infection. Tight adherence to standard preventive measures to minimize the transmission of these pathogens can lead to a decline in the incidence of these infections. Screening should be done widely to control and optimally manage these infections.

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Association of quality of life, anxiety, and depression with restless leg syndrome in the hemodialysis patients

Cited by 6 publications

References 22 publications

Restless leg syndrome and associated factors in patients with end-stage renal disease on haemodialysis.

Restless leg syndrome and associated factors in patients with end-stage renal disease on haemodialysis.

Incidence of Restless Legs Syndrome in Pakistan and Its Relationship With Depression, Gender, and Age: A Cross-Sectional Study

Seroprevalence of Hepatitis B Virus and Hepatitis C Virus in Patients Undergoing Maintenance Hemodialysis

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