Association of preeclampsia with high birth weight for age

Xiong, Xu; Demianczuk, Nestor; Buekens, Pierre; Saunders, L. Duncan

doi:10.1016/s0002-9378(00)24793-5

Cited by 148 publications

(98 citation statements)

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“…Finally, our findings might not be applicable to preterm and low-birth-weight children born to PIH mothers who exhibit preterm birth and intrauterine growth restriction. 34,35 Because our study population consists primarily of term children, our results could be applied to term children born to PIH mothers.…”

Section: Discussionmentioning

confidence: 99%

Relationship between maternal gestational hypertension and home blood pressure in 7-year-old children and their mothers: Tohoku Study of Child Development

et al. 2015

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Women who had hypertensive disorders in pregnancy have an increased risk of cardiovascular diseases in later life. No studies, however, have investigated whether maternal hypertensive disorders in pregnancy affect self-measured blood pressure at home (HBP) in mothers and their children. We evaluated the association between maternal hypertension during pregnancy and HBP based on the prospective Tohoku Study of Child Development birth cohort study, which was performed in two areas in Japan. We included children in a singleton birth at term (36-42 weeks of gestation) with a birth weight of >2400 g. We collected prenatal care data from the medical charts. Because only two mothers experienced preeclampsia, we defined gestational hypertension (GH) as a hypertensive disorder in pregnancy. Seven years after birth, mothers and their children measured their HBP in the morning for 2 weeks. Of 813 eligible mothers, 28 (3.4%) experienced GH, and those were of a similar age compared with 785 non-GH mothers (37.3 vs. 38.0 years; P=0.41). Women with GH had higher body mass index (BMI) (23.8 vs. 21.4 kg m(-)(2); P=0.01) and elevated HBP (120.3/76.8 vs. 110.4/68.6 mm Hg; P<0.0002) 7 years after delivery. However, HBP was similar in children with and without GH mothers (93.5/55.9 vs. 94.1/56.1 mm Hg, P>0.38). These results were confirmatory in case-control (1:2) analyses with matching by maternal age, maternal BMI before pregnancy, survey area and parity. In conclusion, maternal GH did not affect HBP in offspring but strongly affected maternal HBP even 7 years after birth.

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Section: Discussionmentioning

confidence: 99%

Relationship between maternal gestational hypertension and home blood pressure in 7-year-old children and their mothers: Tohoku Study of Child Development

et al. 2015

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“…It is important to recognize that both mortality and morbidity rates increase significantly in very large babies (women who produce neonates greater than 4.2 kg in weight, for example, are more likely to experience both hypertension and preeclampsia: Xiong et al 2000). Stabilizing selection of this kind is, of course, a common feature of biological systems and to be expected (with specific reference to stature in humans, see Nettle 2002aNettle , 2002b.…”

Section: Discussionmentioning

confidence: 99%

“…To ensure homogeneity of the sample, only mothers with healthy babies aged between 9.75 months and 15.5 months who lived in Wroctaw and were visiting the clinic for routine pediatric checks were included in the sample. Because very high neonate weight (>4.2 kg) is a risk factor (Xiong et al 2000), 15 infants with birth weights exceeding 4.2 kg were excluded from the analyses (although, in practice, with such a small number relative to sample size, including them does not change the results of the statistical analyses or the conclusions). In addition, 245 multipares (including cases of twins) were excluded because parity influences body shape; a further 109 cases were excluded because the mother could not recall the exact gestation length (21 cases), pre-pregnant waist or hip girths (56 women), pre-pregnant body weight and/or height, or failed to give their age (32 women).…”

Section: Methodsmentioning

confidence: 99%

Waist-to-hip ratio versus body mass index as predictors of fitness in women

Pawłowski

Dunbar

2005

Hum Nat

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The claim that men prefer women with low waist-to-hip ratios (WHR) has been vigorously disputed. We examine self-report data from 359 primiparous Polish women (with normal singleton births and healthy infants) and show that WHR correlates with at least one component of a woman's biological fitness (her first child's birth weight, a variable that significantly affects infant survival rates). However, a woman's Body Mass Index (BMI) is a better predictor of her child's neonatal weight in small-bodied women (<54 kg). The failure to find a preference for low WHR in some traditional populations may thus be a consequence of the fact that, even in western populations, body mass is a better predictor of fitness in those cases characterized by low maternal body weight.

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“…Preeclampsia, known as the ''disease of theories,'' may be more than one disease of heterogeneous origin with early and late onset patients who vary by severity of disease [73 -75] and who deliver neonates at risk of SGA or LGA. [76,77] Increased cardiac output of late-onset preeclamptics may enhance uteroplacental profusion, which increases the risk of delivering LGA neonates, while severe, early-onset patients may experience reduced uteroplacental profusion, which increases the risk of delivering SGA. [76] Levels of dehydroepiandosterone sulfate (DHEAS) in the cord blood of neonates are highest in severe hypertensives in pregnancy, intermediate in the moderate hypertensives, and lowest in mild hypertensives who have comparable levels to neonates of normotensive women.…”

Section: The Fetal Period: Preterm Birthsmentioning

confidence: 99%

“…[76,77] Increased cardiac output of late-onset preeclamptics may enhance uteroplacental profusion, which increases the risk of delivering LGA neonates, while severe, early-onset patients may experience reduced uteroplacental profusion, which increases the risk of delivering SGA. [76] Levels of dehydroepiandosterone sulfate (DHEAS) in the cord blood of neonates are highest in severe hypertensives in pregnancy, intermediate in the moderate hypertensives, and lowest in mild hypertensives who have comparable levels to neonates of normotensive women. [78,79] Within strata of birthweight-forgestational age, cord blood levels of IGF-1 are lower, but levels of IGFBP-1 and leptin are higher in offspring of severe preeclamptics than in normotensive controls.…”

Section: The Fetal Period: Preterm Birthsmentioning

confidence: 99%

Through the Looking Glass at Early-Life Exposures and Breast Cancer Risk

Forman

Cantwell

Ronckers

et al. 2005

Cancer Investigation

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The global increase in the proportion of women diagnosed with breast cancer, inadequate access to screening and high cost of treatment for breast cancer argue strongly for a greater focus on preventive strategies. But at what age is it appropriate to begin targeting preventive approaches? The recognized role of perinatal nutrition in neurologic development and the relation of maternal nutritional status to birthweight and subsequent risk of hypertension, diabetes, and cardiovascular disease identify pregnancy and early childhood as potential phases for prevention. This review examines indicators of hormonal and nutritional exposures in early life and breast cancer risk through the lens of the life course paradigm integrated with maternal and child health research and methodology. Compared to women who were normal birthweight (2500-3999 g), women who weighed>or=4,000 g at birth have a 20 percent to 5-fold increased risk of premenopausal breast cancer. Women born preterm and likely to be small- or large-for-date also have an increased risk. Birth length is directly associated with risk and has a larger magnitude of effect than birthweight. Prior preeclamptics and their daughters have a lower risk of breast cancer than comparable normotensives. An association between infant feeding practices and breast cancer is unclear without improved exposure assessment and analysis. Rapid childhood and pubertal linear growth increases breast cancer risk, while greater body fat over the same periods reduces risk. Growth data thus far have not been calculated in Z-scores from reference growth curves for comparison across studies. Events and secular trends influencing birth cohorts may not be adequately addressed, thereby limiting the interpretation and implications of the findings. Research in nonhuman primates may help uncover underlying mechanisms.

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Association of preeclampsia with high birth weight for age

Cited by 148 publications

References 0 publications

Relationship between maternal gestational hypertension and home blood pressure in 7-year-old children and their mothers: Tohoku Study of Child Development

Relationship between maternal gestational hypertension and home blood pressure in 7-year-old children and their mothers: Tohoku Study of Child Development

Waist-to-hip ratio versus body mass index as predictors of fitness in women

Through the Looking Glass at Early-Life Exposures and Breast Cancer Risk

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