Association of preeclampsia with high birth weight for age

Fetal Outcome in Hypertensive Disorders of Pregnancy.

“…This fi nding is comparable with a retrospective cohort study done by Xiong X, Mayes D, et al from China found the adjusted odds ratios of low birth weight were 2.65 (1.73-4.39) for preeclampsia and 2.53 (1.19-4.93) for severe preeclampsia, even though the risk of low birth weight was not increased signifi cantly for gestational hypertension (adjusted odds ratio 1.56 [1.00-2.41]) as compared with pre eclampsia 4 . Even, Xiong X and associate in Canada have found that women with preeclampsia were at markedly higher risk of having low birth weight (adjusted odds ratio, 4.14; 95% confi dence interval, 3.32-5.15) and small for gestational age (adjusted odds ratio 2.56; 95% confi dence interval, 1.92-3.41) babies 5 . These facts indicate that preeclampsia increases the risk of MJ SBH J a nu ary -J un e 2 013 | Vo l 1 2| Is s u e 1 intrauterine growth restriction and low birth weight.…”

Retraction: Etiopathology of preeclampsia — Recent progress from the perspective of a poor/ischemic placenta

“…87) There is also a mixture of conditions, ranging from mild preeclampsia with moderate placental involvement to gestational hypertension without placental dysfunction. 88) Late-onset preeclampsia is frequently associated with fetuses that are appropriate-or large-for gestational age, 18,89) multiple gestation, gestational diabetes mellitus (GDM), and primigravida. In these cases, increased fetal demand for substrates that surpasses the placental ability to sustain fetal growth may induce fetal signaling for placental overproduction of antiangiogenic factors and subsequent 'compensatory' maternal hypertension.…”

Effects of Different Grades of Pih on Pregnancy Outcome

“…Proteinuria may be a marker for vascular damage and diminished maternal blood flow to the foetus could result in foetal hypoxia and growth restriction. These may explain why some patients with preeclampsia deliver SGA and low-birth weight infants [5].…”

“…Because of the decrease uteroplacental blood perfusion, it is intuitive that preeclampsia will result in a detrimental effect on fetal growth, leading to intrauterine growth restriction and low birth weight [5].…”