“…Most studies focused on rs2046934 (T744C) or rs6809699 (G52T) representing dbSNP rs10935838, rs2046934, rs5853517 and rs6809699, and rs6785930 (C34T). Some found that it can modulate platelet response to clopidogrel or affect patients' outcomes (Fontana et al, 2003;Zee et al, 2008;Staritz et al, 2009;Shalia et al, 2013;Zoheir et al, 2013;Li et al, 2016), but most results were negative (Angiolillo et al, 2005;Smith et al, 2006;Cuisset et al, 2007;Lev et al, 2007;Bierend et al, 2008;Bonello et al, 2010;Jang et al, 2012;Namazi et al, 2012;Kar et al, 2013;Kim et al, 2013;Jana et al, 2014). Our results show that the P2RY12 allele rs2046934 (T744C) was not significantly associated with HTPR neither in the total study population nor in nonsmokers.…”