Association of Physical Activity and Sedentary Behavior With the Risk of Colorectal Cancer

An, Sang Hyun; Park, Sungjin

doi:10.3346/jkms.2022.37.e158

Cited by 9 publications

(6 citation statements)

References 36 publications

(35 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Participants were asked their histories of the intensity of PA and sedentary behavior using the Korean version of the modified Global Physical Activity Questionnaire whose validity was verified in a previous study [ 17 , 18 , 19 ]. Regarding high PA, participants were asked the following questions: “On how many days in the typical week and how much time a day did you do the work-related, high-intensity physical activity at least 10 min at once?”, “On how many days in the typical week and how much time a day did you do the high-intensity sports, exercise, or leisure time activity at least 10 min at once?”.…”

Section: Methodsmentioning

confidence: 99%

Physical Activity and Sedentary Time in Korean Adults before and during the COVID-19 Pandemic Using Data from the Korea National Health and Nutritional Examination Survey

Kim

Yoo

Kwon

et al. 2022

JPM

View full text Add to dashboard Cite

Several recent studies suggested reduced physical activity (PA) related to the COVID-19 pandemic without consensus. This study investigated the changes in PA and sedentary time during the COVID-19 pandemic compared to before the COVID-19 era. The Korea National Health and Nutrition Examination Survey 2019 and 2020 were used. The ≥19-year-old population was examined in 2019 and 2020 for time spent engaging in high- and moderate-intensity PA and sedentary time. Based on the recommended level of PA by the World Health Organization, ≥75 min/wk of high PA and ≥150 min/of moderate PA were classified. A sedentary time of ≥120 min/d was selected. Multiple logistic regression analysis with complex sampling was conducted for ≥75 min/wk of high PA, ≥150 min/wk of moderate PA, and ≥120 min/d of sedentary time in the 2020 group compared to the 2019 group. The ≥75 min/wk high PA was not lower in the 2020 group than in the 2019 group (adjusted odds ratio (aOR) = 0.96, 95% confidence intervals (95% CIs) = 0.79–1.18, P = 0.696). The ≥150 min/wk of moderate PA was also not lower in the 2020 group (aOR = 1.12, 95% CI = 0.94–1.32, p = 0.201). However, the ≥150 min/wk of moderate PA in the female group was higher in the 2020 group than in the 2019 group (aOR = 1.29, 95% CI = 1.01–1.65, p = 0.042). Sedentary time ≥ 120 min/d was lower in the 2020 group (aOR = 0.35, 95% CI = 0.17–0.72, p = 0.005). This association was consistent in the 19–39-year-old and female group. In conclusion, during the COVID-19 pandemic, high and moderate PA were not decreased in Korean adults, while sedentary time was reduced.

show abstract

Section: Methodsmentioning

confidence: 99%

Physical Activity and Sedentary Time in Korean Adults before and during the COVID-19 Pandemic Using Data from the Korea National Health and Nutritional Examination Survey

Kim

Yoo

Kwon

et al. 2022

JPM

View full text Add to dashboard Cite

show abstract

“…Numerous results demonstrate an increased incidence of CRC in advanced and growing countries, which could also be attributed to physical inactivity. Studies show that physically inactive individuals are approximately 50% more likely to develop the disease than individuals with regular exercise (OR, 1.49; 95% CI, 1.02–2.16) [ 211 , 212 ]. A recent meta-analysis revealed that constant and intense physical exercise could induce a reduction in the risk of colorectal cancer by 19% and 12%, respectively [ 213 ].…”

Section: Lifestyle and Colorectal Cancermentioning

confidence: 99%

Healthy Lifestyle and Cancer Risk: Modifiable Risk Factors to Prevent Cancer

Marino,

Mininni,

Deiana

et al. 2024

Nutrients

View full text Add to dashboard Cite

Cancer has become a serious problem worldwide, as it represents the main cause of death, and its incidence has increased over the years. A potential strategy to counter the growing spread of various forms of cancer is the adoption of prevention strategies, in particular, the use of healthy lifestyles, such as maintaining a healthy weight, following a healthy diet; being physically active; avoiding smoking, alcohol consumption, and sun exposure; and vitamin D supplementation. These modifiable risk factors are associated with this disease, contributing to its development, progression, and severity. This review evaluates the relationship between potentially modifiable risk factors and overall cancer development, specifically breast, colorectal, and prostate cancer, and highlights updated recommendations on cancer prevention. The results of numerous clinical and epidemiological studies clearly show the influence of lifestyles on the development and prevention of cancer. An incorrect diet, composed mainly of saturated fats and processed products, resulting in increased body weight, combined with physical inactivity, alcohol consumption, and smoking, has induced an increase in the incidence of all three types of cancer under study. Given the importance of adopting correct and healthy lifestyles to prevent cancer, global institutions should develop strategies and environments that encourage individuals to adopt healthy and regular behaviors.

show abstract

“…These genes have multiple functions and affect tumor biology through various biological processes, including proliferation, homeostasis, migration, cell adhesion, immunity, and microbial interactions (7). Previous studies also found that environmental risk factors, Sedentary behavior (RR: 1.30, 95% CI: 1.22-1.39) (8) and smoking (RR: 1.17; 95% CI: 1.15-1.20) (9), could potentially impact the risk of CRC. Notably, in the realm of diet and nutrition, many experimental and epidemiological studies have made significant findings.…”

Section: Introductionmentioning

confidence: 98%

Causal associations between dietary factors and colorectal cancer risk: a Mendelian randomization study

Zhang,

Wu,

Wang

et al. 2024

Front. Nutr.

View full text Add to dashboard Cite

BackgroundPrevious epidemiological studies have found a link between colorectal cancer (CRC) and human dietary habits. However, the inherent limitations and inevitable confounding factors of the observational studies may lead to the inaccurate and doubtful results. The causality of dietary factors to CRC remains elusive.MethodsWe conducted two-sample Mendelian randomization (MR) analyses utilizing the data sets from the IEU Open GWAS project. The exposure datasets included alcoholic drinks per week, processed meat intake, beef intake, poultry intake, oily fish intake, non-oily fish intake, lamb/mutton intake, pork intake, cheese intake, bread intake, tea intake, coffee intake, cooked vegetable intake, cereal intake, fresh fruit intake, salad/raw vegetable intake, and dried fruit intake. In our MR analyses, the inverse variance weighted (IVW) method was employed as the primary analytical approach. The weighted median, MR-Egger, weighted mode, and simple mode were also applied to quality control. Heterogeneity and pleiotropic analyses were implemented to replenish the accuracy of the results.ResultsMR consequences revealed that alcoholic drinks per week [odds ratio (OR): 1.565, 95% confidence interval (CI): 1.068–2.293, p = 0.022], non-oily fish intake (OR: 0.286; 95% CI: 0.095–0.860; p = 0.026), fresh fruit intake (OR: 0.513; 95% CI: 0.273–0.964; p = 0.038), cereal intake (OR: 0.435; 95% CI: 0.253–0.476; p = 0.003) and dried fruit intake (OR: 0.522; 95% CI: 0.311–0.875; p = 0.014) was causally correlated with the risk of CRC. No other significant relationships were obtained. The sensitivity analyses proposed the absence of heterogeneity or pleiotropy, demonstrating the reliability of the MR results.ConclusionThis study indicated that alcoholic drinks were associated with an increased risk of CRC, while non-oily fish intake, fresh fruit intake, cereal intake, and dried fruit were associated with a decreased risk of CRC. This study also indicated that other dietary factors included in this research were not associated with CRC. The current study is the first to establish the link between comprehensive diet-related factors and CRC at the genetic level, offering novel clues for interpreting the genetic etiology of CRC and replenishing new perspectives for the clinical practice of gastrointestinal disease prevention.

show abstract

Association of Physical Activity and Sedentary Behavior With the Risk of Colorectal Cancer

Cited by 9 publications

References 36 publications

Physical Activity and Sedentary Time in Korean Adults before and during the COVID-19 Pandemic Using Data from the Korea National Health and Nutritional Examination Survey

Physical Activity and Sedentary Time in Korean Adults before and during the COVID-19 Pandemic Using Data from the Korea National Health and Nutritional Examination Survey

Healthy Lifestyle and Cancer Risk: Modifiable Risk Factors to Prevent Cancer

Causal associations between dietary factors and colorectal cancer risk: a Mendelian randomization study

Contact Info

Product

Resources

About