Association of PD-1 gene with outcome of hepatitis C virus infection

Sarvari, Jamal; Dowran, Razieh; Hosseini, Seyed Younes; Fattahi, Mohammad Reza; Erfani, Nasrollah

doi:10.17179/excli2018-1394

Cited by 4 publications

(3 citation statements)

References 37 publications

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“…Additionally, the HCV core protein was found to stimulate substantial PD-L1 up-regulation in vitro on primary human Kupffer cells as well as monocytes. These could be essential mechanisms for the viral immune escape and its persistence during chronic HCV infection [ 17 , 18 ].…”

Section: Discussionmentioning

confidence: 99%

Programmed death-ligand 1 (PD-L1) polymorphisms as predictive biomarkers for the development of liver cirrhosis and hepatocellular carcinoma in HCV Egyptian patients

Hassan¹,

Attia²,

Ali-Eldin³

et al. 2022

Tumour Virus Research

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Section: Discussionmentioning

confidence: 99%

Programmed death-ligand 1 (PD-L1) polymorphisms as predictive biomarkers for the development of liver cirrhosis and hepatocellular carcinoma in HCV Egyptian patients

Hassan¹,

Attia²,

Ali-Eldin³

et al. 2022

Tumour Virus Research

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“…[ 1 2 ] Chronic infection of HBV and HCV might progress to end-stage liver diseases including cirrhosis and hepatocellular carcinoma. [ 3 4 ] The endemicity of HBV and HCV infections varies in different parts of the world. Iran with a prevalence of less than 2% and 0.5% of chronic HBV and HCV infections, respectively, has had the low burden of these diseases among countries.…”

mentioning

confidence: 99%

“…Iran with a prevalence of less than 2% and 0.5% of chronic HBV and HCV infections, respectively, has had the low burden of these diseases among countries. [ 3 4 ] Moreover, in 2018, 3492 liver cancer cases (11 th ) and 3439 death related to liver cancer (7 th ) were reported in Iran. [ 5 ]…”

mentioning

confidence: 99%

The sero-prevalence of hepatitis b and c viruses in municipal waste collectors in Southwest of Iran

Hosseini,

Sarvari,

Joharinia

et al. 2023

Indian J Occup Environ Med

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Aims: The present study aimed to investigate the frequency of hepatitis B virus (HBV) and hepatitis C virus (HCV) serological markers among waste collectors in the municipality of Shiraz city, southwest of Iran, 2018. Settings and Design: In this cross-sectional study, a total of 385 waste collectors from all 10 districts of Shiraz city, southwest of Iran were enrolled. A questionnaire was used to gather occupational and demographic information as well as awareness about viral hepatitis. Methods and Material: Their blood samples were collected, and the sera were investigated for the presence of hepatitis B surface antigen (HBsAg), anti-HBs antibody, and anti-HCV antibody using enzyme-linked immunosorbent assay (ELISA). Results: All the participants were men with a mean age of 41 ± 8 years. Out of 385 participants, 6 (1.5%) subjects were positive for HBsAg, indicative of HBV infection. Moreover, 38 (9.9%) had a protective level of anti-HBs antibodies, while more than 90% had a low level of anti-HBs antibodies. All participants were negative for HCV antibodies. Conclusion: According to these findings, evaluation of HBsAg and anti-HBs levels is recommended in the healthy program of waste collector workers (WCWs). However, this occupation might not be a risk factor for the acquisition of HBV and especially HCV infections.

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Current editorial challenges: Criteria for selecting articles for publication

Hengstler

2019

EXCLI Journal; 18:Doc1101; ISSN 1611-2156

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Association of PD-1 gene with outcome of hepatitis C virus infection

Cited by 4 publications

References 37 publications

Programmed death-ligand 1 (PD-L1) polymorphisms as predictive biomarkers for the development of liver cirrhosis and hepatocellular carcinoma in HCV Egyptian patients

Programmed death-ligand 1 (PD-L1) polymorphisms as predictive biomarkers for the development of liver cirrhosis and hepatocellular carcinoma in HCV Egyptian patients

The sero-prevalence of hepatitis b and c viruses in municipal waste collectors in Southwest of Iran

Current editorial challenges: Criteria for selecting articles for publication

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