IN JUNE 2022, the Center for Medicare and Medicaid Innovation (CMMI) announced the application period for the Enhancing Oncology Model (EOM), 1 the successor value-based payment model for medical oncology that followed the conclusion of CMMI's Oncology Care Model (OCM). During the application period there was skepticism about the model among potential participants, but also overwhelming optimism and interest in fi guring out how to navigate several profound challenges in EOM design relative to OCM. 2,3 The high number of EOM applicants represented clear evidence of such interest. 4