Association of participation in the Northern Finland Birth Cohort 1986 with mental disorders and suicidal behaviour

Kerkelä, Martta; Gissler, Mika; Veijola, Juha

doi:10.4178/epih.e2022005

Cited by 2 publications

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“…The participation bias in epidemiological follow-up studies has previously been under-examined, and the results need to be replicated. In a previous study, an association between the use of mental health care services and participation in the NFBC1986 study was found [ 35 ].…”

Section: Discussionmentioning

confidence: 99%

Association between participation in the Northern Finland Birth Cohorts and cardiometabolic disorders

et al. 2023

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Background We studied the association between participation in the longitudinal follow-up study and cardiometabolic disorders in two longitudinal studies which started prospectively in the antenatal period: the Northern Finland Cohort 1966 (NFBC1966) and the Northern Finland Birth Cohort 1986 (NFBC1986). Both birth cohorts have been followed up since birth with multiple follow-ups including questionnaires, and clinical examinations. Methods The NFBC studies were compared to comparison cohorts of individuals who were born in the same area as the study cohorts, but in different years. The data for the comparison cohort were obtained from registers. The cumulative incidence rates of hospital-treated cardiometabolic disorders were calculated for study and comparison cohorts covering the age of 7–50 years in NFBC1966 and the age of 0–29 years in NFBC1986. Cardiometabolic-related causes of death were analysed in NFBC1966 and the comparison cohort from the age of 0–50 years. The analysed cardiometabolic disorders were diabetes mellitus, coronary artery disease, hyperlipidaemia, obesity, hypertension, and cerebrovascular disorders. The risk ratio (RR) with 95% confidence intervals (CI) was calculated by sex. Results In NFBC1966, no differences in cumulative incidences of cardiometabolic disorders or cardiometabolic-related deaths compared to the comparison cohort were found. Male members of NFBC1986 had decreased risk of obesity (RR: 0.45, 95% CI: 0.27–0.75) and any cardiometabolic disorders (RR: 0.75, 95% CI: 0.59–0.95) compared to the comparison cohort. Conclusions The results suggest that participation in the NFBC1986 may have a weak positive health effect among men. Agreement to follow-up studies focusing on diet, substance use, and physical activity, may slightly decrease the incident risk of cardiometabolic disorders in the study population. KEY MESSAGES Even mild interventions, such as follow-up studies in the prospective follow-up studies, might affect participants’ behaviour and consequently the incidence of cardiometabolic disorders The fact that follow-up itself might affect the study population in terms of risk factors, has to be taken into account when estimating the representativeness of the followed population.

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Section: Discussionmentioning

confidence: 99%

Association between participation in the Northern Finland Birth Cohorts and cardiometabolic disorders

et al. 2023

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“…A previous study did find an association between the Northern Finland Birth Cohort 1986 (NFBC1986) and mental disorders; the female members of the NFBC1986 had less psychiatric diagnoses at age 2 to 28 years than the comparison cohort [39]. Both of the NFBC studies are prospective longitudinal birth cohorts with multiple follow-ups.…”

Section: Plos Onementioning

confidence: 99%

Association between participation in the Northern Finland Birth Cohort 1966 study and use of psychiatric care services

Kerkelä

Gissler²,

Nordström³

et al. 2023

PLoS ONE

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Aims In most population-based epidemiological follow-up studies the aim is not to intervene in the life of the participants. Although the idea is not to intervene, being a member of the longitudinal follow-up study and studies conducted during follow-up may affect the target population. A population-based study including mental health enquiries might reduce the unmet need for psychiatric treatment by motivating people to seek treatment for their psychiatric ill-health. We examined the use of psychiatric care services in the population born in the year 1966 in Northern Finland, of whom 96.3% are participants in the prospective Northern Finland Birth Cohort 1966 (NFBC1966). Methods As a study cohort we used people born in 1966 in Northern Finland (n = 11 447). The comparison cohort included all the people born in the years 1965 and 1967 in the same geographical area (n = 23 339). The follow-up period was from age 10 to 50 years. The outcome measure was the use of psychiatric care services, which was analysed using Cox Proportional Hazard regression and Zero-Truncated Negative Binomial Regression. Results People born in 1966 in Northern Finland did not differ from those born in 1965 and 1967 in terms of the outcome measure. Conclusions We found no association between participation in an epidemiological follow-up study and the use of psychiatric care services. The NFBC1966 may be regarded as a representative at the population level in terms of psychiatric outcomes despite the personal follow-up of the birth cohort. The associations of participation in epidemiological follow-up studies have previously been under-examined, and the results need to be replicated.

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Association of participation in the Northern Finland Birth Cohort 1986 with mental disorders and suicidal behaviour

Cited by 2 publications

References 46 publications

Association between participation in the Northern Finland Birth Cohorts and cardiometabolic disorders

Association between participation in the Northern Finland Birth Cohorts and cardiometabolic disorders

Association between participation in the Northern Finland Birth Cohort 1966 study and use of psychiatric care services

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