Association of neonatal respiratory distress with birth asphyxia and deficiency of red cell mass in premature infants

Linderkamp, Otwin; Versmold, Hans T.; Fendel, H; Riegel, K; Betke, Klaus

doi:10.1007/bf00442160

Cited by 34 publications

(15 citation statements)

References 32 publications

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“…This difference was not due to differences in birth weight or gestational age. It might have been due only to biologic variation or to a higher degree of birth asphyxia in the severe HMD group [12]. Unfortunately, Apgar scores from 5 study patients were not avail able, so this hypothesis could not be tested.…”

Section: Discussionmentioning

confidence: 99%

Different Patterns of Pulmonary Sequelae after Hyaline Membrane Disease: Heterogeneity of Bronchopulmonary Dysplasia?

Lierde

Cornelis²,

Devlieger³

et al. 1991

Neonatology

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In an autopsy study of 37 infants who suffered from hyaline membrane disease (HMD), two distinct patterns of pulmonary lesions could be defined. One pattern, characterized by marked interstitial fibrosis in the absence of airway abnormalities, was labelled Ê»interstitial-type’ histology. A second type, labelled Ê»bronchiolar-type’ histology, showed marked airway lesions and alveolar emphysema. Nine patients of each type were analysed. Nineteen other patients had a Ê»mixed-type’ histology and were not further studied. Retrospectively, the clinical and radiological characteristics of both series were analysed. No differences in birth weight, gestational age and initial radiological HMD grade could be demonstrated. The pulmonary function of the bronchiolar-type patients however was significantly worse at the onset, and these infants needed more oxygen and ventilatory support during the first 10 days of life. They all died from respiratory failure whereas 4 patients from the interstitial group had non-pulmonary fatalities. In the bronchiolar group chest X-rays showed atelectasis and pulmonary interstitial emphysema in the early stages, and hyperinflation with bullae and irregular streaky densities in the later. Patients in the interstitial group had no or minor emphysema with more homogeneously spread densities over both lungs. We conclude that both types of evolution represent two extremes of the bronchopulmonary dysplasia spectrum.

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Section: Discussionmentioning

confidence: 99%

Different Patterns of Pulmonary Sequelae after Hyaline Membrane Disease: Heterogeneity of Bronchopulmonary Dysplasia?

Lierde

Cornelis²,

Devlieger³

et al. 1991

Neonatology

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“…10 of the infants had received exchange transfusion immediate ly after birth. It is possible that some of these have been hypovolemic [29], but also the dy namic control of blood pressure may have been insufficient. Exchange transfusion increases colloid osmotic pressure in infants [30] and may have effects on the intravascular volume and blood pressure.…”

Section: Discussionmentioning

confidence: 99%

“…The number of infants receiving exchange transfusion was similar in all groups, and we think that it does not explain the intergroup differences. Infants with intra partum asphyxia do not participate in placen tal transfusion [29], which greatly modifies the neonatal blood volume [31]. Hypovolemia must be kept in mind as a cause of low ar terial blood pressure in these infants, especi ally in connection with poor peripheral circu lation and postnatal fall in hemoglobin [29].…”

Section: Discussionmentioning

confidence: 99%

Cardiovascular Monitoring in Infants with Respiratory Distress Syndrome

Korvenranta¹,

Kero²,

Välimäki³

1983

Neonatology

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Heart rate, short-term heart rate variability, long-term heart rate variability (LTV), mean arterial blood pressure and R-to-pulse time were recorded in 28 infants during the acute phase of respiratory distress syndrome (RDS). The patients were classified by a clinical scoring system into three classes related to the severity of the disease. The LTV was initially significantly (p < 0.01) lower in infants with severe RDS (class III) than in those with moderate or mild disease (classes II and I). Only in class III the LTV increased significantly (p < 0.001) during recovery. Also the mean arterial blood pressure was decreased in class III during the first 24 h of life. The R-to-pulse time proved not to be related to the severity of RDS. Reasonable assistance was achieved by multiparametric circulatory monitoring: a considerably disturbed circulatory control (tendency to hypotension and attenuated chronotropic cardiac control) was observed in the most severe form of RDS. No specific circulatory therapy was applied on the basis of the findings.

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“…[8][9][10] Other studies indicated that ECC prevented placental transfusion and resulted in more respiratory distress syndrome among preterm infants. [11][12][13] Importantly, in settings with a high prevalence of HIV infection, immediate CC has been thought to reduce the risk of mother-to-child transmission. Furthermore, active management of third-stage labor, including use of oxytocin, together with ECC within 30 to 60 seconds and controlled cord traction, is considered important in the prevention of postpartum bleeding.…”

mentioning

confidence: 99%

Neonatal Outcome Following Cord Clamping After Onset of Spontaneous Respiration

et al. 2014

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BACKGROUND AND OBJECTIVE: Evolving data indicate that cord clamping (CC) beyond 30 to 60 seconds after birth is of benefit for all infants. Recent experimental data demonstrated that ventilation before CC improved cardiovascular stability by increasing pulmonary blood flow. The objective was to describe the relationship between time to CC, onset of spontaneous respirations (SR), and 24-hour neonatal outcome. METHODS: In a rural Tanzanian hospital, trained research assistants, working in shifts, have observed every delivery (November 2009–February 2013) and recorded data including time interval from birth to SR and CC, fetal heart rate, perinatal characteristics and outcome (normal, death, admission). RESULTS: Of 15 563 infants born, 12 780 (84.3%) initiated SR at 10.8 ± 16.7 seconds, and CC occurred at 63 ± 45 seconds after birth. Outcomes included 12 730 (99.7%) normal, 31 deaths, and 19 admitted; 11 967 were of birth weight (BW) ≥2500 g and 813 <2500 g. By logistic modeling, the risk of death/admission was consistently higher if CC occurred before SR. Infants of BW <2500 g were more likely to die or be admitted. The risk of death/admission decreased by 20% for every 10-second delay in CC after SR; this risk declined at the same rate in both BW groups. CONCLUSIONS: Healthy self-breathing neonates are more likely to die or be admitted if CC occurs before or immediately after onset of SR. These clinical observations support the experimental findings of a smoother cardiovascular transition when CC is performed after initiation of ventilation.

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Association of neonatal respiratory distress with birth asphyxia and deficiency of red cell mass in premature infants

Cited by 34 publications

References 32 publications

Different Patterns of Pulmonary Sequelae after Hyaline Membrane Disease: Heterogeneity of Bronchopulmonary Dysplasia?

Different Patterns of Pulmonary Sequelae after Hyaline Membrane Disease: Heterogeneity of Bronchopulmonary Dysplasia?

Cardiovascular Monitoring in Infants with Respiratory Distress Syndrome

Neonatal Outcome Following Cord Clamping After Onset of Spontaneous Respiration

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