Abstract:Background: Limited and contradictory pharmacogenetic studies of NPHS2 gene R229Q polymorphism in nephrotic syndrome (NS) children and adults of different ethnicities steered us to investigate the genotype frequency and associated risk of this polymorphism in Middle East NS children and adults. Objectives: The present work aimed to study the effect of NPHS2 R229Q genetic variations on the susceptibility to idiopathic NS and the treatment response in NS children and adults from Assiut University and major Kuwai… Show more
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