Association of Military Training with Oxidative Stress and Overreaching

Tanskanen, Minna; Uusitalo, Arja; Kinnunen, Hannu; Häkkinen, Keijo; Kyröläinen, Heikki; Atalay, Mustafa

doi:10.1249/mss.0b013e3182106d81

Cited by 37 publications

(46 citation statements)

References 33 publications

(44 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Phagocytic cells (e.g., neutrophils, monocytes and macrophages) that infiltrate damaged muscle fibres and other active tissues during exercise may generate large quantities of ROS that deplete extracellular antioxidants, promoting the activity and release of endogenous antioxidants into the circulation. The resulting changes in resting oxidative stress may also modulate the acute oxidative stress response to exercise, with reports of exaggerated (Palazzetti et al 2003;Tanskanen et al 2011) and suppressed (Tanskanen et al 2010) oxidative stress observed following acute exercise challenges in athletes undergoing IT. These inconsistencies can be attributed to the range of study designs utilised, with respect to the duration and intensity of the IT period, and also the timing of blood measures following the change in overload stimulus.…”

Section: Introductionmentioning

confidence: 99%

The impact of intensified training with a high or moderate carbohydrate feeding strategy on resting and exercise-induced oxidative stress

et al. 2015

View full text Add to dashboard Cite

Additional Information:• 41of increase in PC and LOOH was greater on days 6 and 10 compared to day 2 in both conditions. 42Conclusions: Short-term IT caused reductions in resting antioxidant capacity in trained cyclists. Exercise- 43induced increases in PC and LOOH were exaggerated as a result of IT; however, these responses were 44 independent of carbohydrate intake before, during and after the preceding IT sessions. 46

show abstract

Section: Introductionmentioning

confidence: 99%

The impact of intensified training with a high or moderate carbohydrate feeding strategy on resting and exercise-induced oxidative stress

et al. 2015

View full text Add to dashboard Cite

show abstract

“…w sta nie prze mę cze nia i prze treno wa nia (ang. over re aching and over tra ining), gdzie jest ob ser wo wa ny wy so ki po ziom wskaź ni ków stre su oksy da cyj ne go [41,42].…”

Section: Rons and Antioxidantsunclassified

“…W 2000 ro ku, na ła mach Na tu re, Fin kel i Hol bro ok [43], opiera jąc się na kon cep cji zja wi ska hor me zy, wy ra zi li pogląd, że naj lep szą stra te gią an ty ok sy da cyj ną jest stałe na ra ża nie or ga ni zmu na RONS, na to miast ha moresign from using antioxidants in sport. Currently, antioxidants are used in sport in specific situations, i.e., in case of overreaching and overtraining, where there is an observed high level of oxidative stress indicators [41,42].…”

Section: Rons I Zja Wi Sko Hor Me Zyunclassified

“…Sta łe po bu dza nie or ga ni zmu do zwięk szo nej produk cji RONS pod czas sys te ma tycz nych ćwi czeń fizycz nych zwięk sza opor ność ko mó rek na uszko dzenia oksy da cyj ne. Na to miast wy ko na nie in ten syw ne go wy sił ku fi zycz ne go, bez wstęp ne go przy go to wa nia, mo że do pro wa dzić do nad pro duk cji RONS, uszko dzenia ko mó rek, spad ku si ły skur czu mię śni szkie letowych, a na wet prze tre no wa nia [36,41,42,44]. Optymal nym roz wią za niem jest do bór ta kich ob cią żeń pod czas tre nin gu fi zycz ne go, któ re bę dą sty mu lo wać sys te my obron ne i po zwo lą unik nąć ne ga tyw nych skut ków dzia ła nia RONS.…”

Section: Diagram Of the Body's Response To The Generation Of Rons Dunclassified

“…Continuous stimulation of the body to produce more RONS during systematic physical exercises increases the resistance of cells to oxidative damage. However, going through intensive physical exercise, without preliminary preparation, can lead to overproduction of RONS, damaged of cells, drop in strength of contraction of skeletal muscles, and even overtraining [36,41,42,44]. The optimal solution is the selection of such loads, during physical training, that will stimulate defensive systems and help avoid the negative effects of RONS.…”

Section: Rons I Sy Gna Li Za Cja Ko Mór Ko Wamentioning

confidence: 99%

See 2 more Smart Citations

Current Knowledge on Rons and Physical Exercise

Zembroń-Łacny¹,

Kasperska²,

Karolczuk³

2011

Polish J Sport Med

View full text Add to dashboard Cite

Sum ma ry Over the past few years, research studies on reactive oxygen and nitrogen spe cies (RONS) have became a part of intensively developing genomics and proteomics. They have concentrated on hydrogen peroxide (H2O2) and nitric oxide (NO), and their roles in regulation of gene expression. Mechanisms of the processes are based on modulation of transcription factors activity through changes in cell redox status, S-nitrosylation reaction and/or production of second messangers such as cGMP. The effect of increased metabolic H2O2 and NO activity is manifested as a biogenesis of mitochondria, erythropoiesis, an gio genesis, elevated energy metabolism, antioxi dants synthesis and inflammatory mediators, proliferation and differentiation of muscle stem cells (satellite cells), transformationW bio che mii spor tu po ja wił się głów nie dzię ki bada niom Da vie sa i wsp.[1], któ rzy za po mo cą spek trosko pii EPR wy ka za li ge ne ra cję RONS w mię śniach szkie le to wych i zwią za ny z tym spa dek zdol no ści odde cho wych mi to chon driów.Ko lej ne la ta ba dań do star czy ły do wo dów, że wy twarza ne pod czas wy sił ku fi zycz ne go RONS po cho dzą nie tyl ko z ko mó rek mię śnio wych, ale ta kże z ery tro cy tów, ko mó rek śród błon ka na czyń krwio no śnych oraz ko mó -rek im mu no lo gicz nych, a ich źró dłem są re ak cje ka ta lizo wa ne m.in. przez oksy do re duk ta zę NADH, oksy da zę α-hy drok sy kwa sów, li po ok sy ge na zę, cy klo ok sy ge na zę, oksy da zę ksan ty no wą, pe rok sy da zę kwa su ara chi do nowe go, syn ta zę tlen ku azo tu, oksy da zę NADPH oraz reak cje au to ok sy da cji ta kich czą ste czek jak tio le, ka te chola mi ny i biał ka od de cho we [2].W tym okre sie zja wi sko ge ne ra cji re ak tyw nych form tle nu i azo tu, jak anio no rod nik po nad tlen ko wy, nad tle nek azo tu, tle nek azo tu i nad tle no azo tyn czy rod ni ki or ga nicz ne, po strze ga no wy łącz nie ne ga tywnie. Na pod sta wie ba dań, w któ rych wy ka za no wy soki po ziom we krwi i mo czu pro duk tów re ak cji ini cjowa nych przez RONS (m. in. izo pro sta nów, nad tlenków li pi do wych, sko niu go wa nych die nów, grup karbo ny lo wych, ty mi dy ny i 8-hy drok sy gu ani ny) przy pisa no RONS ro lę in duk to rów uszko dzeń oksy da cyjnych i za bu rzeń me ta bo licz nych. Pod kre śla no du ży udział RONS w pro ce sie sta rze nia i roz wo ju ta kich scho rzeń jak cho ro by ser co wo -na czy nio we, cu krzyca, no wo two ry, ar tre tyzm, udar mó zgu i in. [2,3,4,5]. RONS i an ty ok sy dan tyW związ ku z udzia łem re ak tyw nych form tle nu i azo tu w uszko dze niach ko mór ko wych, w la tach 90-tych na stą pi ło du że za in te re so wa nie związ ka mi re duku ją cy mi RONS i osła bia ją cy mi stres oksy da cyj ny. Zi den ty fi ko wa no po nad sto czą ste czek po cho dze nia en do -i eg zo gen ne go, któ rym przy pi sa no funk cje anty ok sy da cyj ne. Szcze gól nie wie le uwa gi po świę co no wi ta mi nie C, wi ta mi nie E, ka ro te no idom i ko en zy mowi Q, głów nie ze wzglę du na wy stę pu ją cy pod czas wy sił ku ...

show abstract

The effect of food ration bar enriched with β‐alanine, L‐arginine, and Nigella sativa on performance and inflammation following intense military training: A double‐blind randomized clinical trial

Hadi

Miryan

Soleimani

et al. 2021

Food Science & Nutrition

View full text Add to dashboard Cite

Background There are growing interests in using dietary supplements to improve athletic performance. This study aimed to evaluate the effect of the food ration bar enriched with β‐alanine, L‐arginine, and Nigella sativa on athletic performance and inflammation following intense military training. Methods This double‐blind, randomized, controlled clinical trial was conducted on 54 new cadets. Eligible participants were randomly assigned in a 1:1 ratio to receive food ration bars enriched with arginine (2 g/day), β‐alanine (2 g/day), and Nigella sativa (2 g/day) or nonenriched food ration bars during a 2‐week military training. Aerobic and anaerobic performances were evaluated by the Cooper and RAST tests, respectively. Results A significant increase in anaerobic powers (min, mean, and max) and a significant reduction in fatigue index were observed in the intervention group as compared to the control group, even after the adjustment for confounding factors. Also, increased levels of hs‐CRP and TNF‐α following military training were significantly lower in the intervention group as compared to the control group (hs‐CRP: 0.55 ± 0.1 versus 2.43 ± 0.1 mg/L; p‐value: 0.01; TNF‐α: 0.12 ± 0.04 versus 0.62 ± 0.04 pg/ml; p‐value: 0.03). No significant changes were observed in VO2 max in both groups. Conclusions Our results showed that the combination of β‐alanine, L‐arginine, and Nigella sativa can improve anaerobic performance and reduce inflammation following intense physical activities. Further studies with long‐term duration are needed to confirm the cumulative/synergic effects of these ingredients in trained and nontrained subjects.

show abstract

Association of Military Training with Oxidative Stress and Overreaching

Abstract: The sustained training load during the last 4 wk of BT led to oxidative stress observable both at rest and after submaximal exercise. Increased oxidative stress may be a marker of insufficient recovery leading possibly to OR.

Cited by 37 publications

References 33 publications

The impact of intensified training with a high or moderate carbohydrate feeding strategy on resting and exercise-induced oxidative stress

The impact of intensified training with a high or moderate carbohydrate feeding strategy on resting and exercise-induced oxidative stress

Current Knowledge on Rons and Physical Exercise

The effect of food ration bar enriched with β‐alanine, L‐arginine, and Nigella sativa on performance and inflammation following intense military training: A double‐blind randomized clinical trial

Contact Info

Product

Resources

About