Association of long-term exposure to PM2.5 with blood lipids in the Chinese population: Findings from a longitudinal quasi-experiment

Li, Jiajianghui; Yao, Yao; Xie, Weixin; Wang, Bin; Guan, Tianjia; Han, Yiqun; Wang, Huiyu; Zhu, Tong; Xue, Tao

doi:10.1016/j.envint.2021.106454

Cited by 46 publications

(36 citation statements)

References 38 publications

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“…During 2013 to 2017, the CHARLS project conducted three waves of surveys in 2011 (before CAP), 2013, and 2015 (after CAP). Using a difference-in-differences approach, the authors found significant associations of PM 2.5 reduction with decreased risk of depression, 90 improved blood lipid levels, and decreased risk of dyslipidemia, 91 as well as reduced medical expenditure. 92 Another quasi-experimental study was conducted based on the CLHLS among 2,812 participants aged 60 years and older from the 2014 and 2018 waves.…”

Section: Epidemiological Evidence On Health Impacts Of Particulates I...mentioning

confidence: 99%

Overview of particulate air pollution and human health in China: Evidence, challenges, and opportunities

et al. 2022

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Section: Epidemiological Evidence On Health Impacts Of Particulates I...mentioning

confidence: 99%

Overview of particulate air pollution and human health in China: Evidence, challenges, and opportunities

et al. 2022

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“…In contrast, before the intervention, there was no significant trend in PM 2.5 (0.29 μg/m 3 /year; 95% CI: -3.66~4.25 μg/m 3 /year) from 2009 to 2012. Spatial distributions of the PM 2.5 trends are documented in our previous publication (17). Detailed summaries of the studied population are presented in Table 1.…”

Section: Resultsmentioning

confidence: 97%

“…This study applied a difference-in-difference method to examine the causal effect of PM 2.5 on kidney function. The same approach has been applied in our previous analyses (17,19) and briefly introduced in supplement (S1.4). For this study, the difference-in-difference analysis was parameterized using the following equation:…”

Section: Study Design and Statisticalmentioning

confidence: 99%

“…As a consequence, annual PM 2.5 concentrations in mainland China have decreased significantly by 32%, from 67.4 μg/m 3 in 2013 to 45.5 μg/m 3 in 2017 (15). This rapid change provides an opportunity of designing quasiexperiments to investigate the beneficial effect of air pollution reduction on the human health in the Chinese population (17)(18)(19). Based on repeated nation-scale surveys launched before and after the Clean Air Action Plan in 2011 and 2015 on the same population of 5115 adults, we conducted a differencein-difference study to investigate the causal relationship between chronic exposure to ambient PM 2.5 and changes in kidney function.…”

Section: Introductionmentioning

confidence: 99%

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Association of PM _2.5 Reduction with Improved Kidney Function: A Nationwide Quasiexperiment among Chinese Adults

et al. 2022

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Background. Increasing evidence from human studies has revealed the adverse impact of ambient fine particles (PM2.5) on health outcomes related to metabolic disorders and distant organs. Whether exposure to ambient PM2.5 leads to kidney impairment remains unclear. The rapid air quality improvement driven by the clean air actions in China since 2013 provides an opportunity for a quasiexperiment to investigate the beneficial effect of PM2.5 reduction on kidney function. Methods. Based on two repeated nationwide surveys of the same population of 5115 adults in 2011 and 2015, we conducted a difference-in-difference study. Variations in long-term exposure to ambient PM2.5 were associated with changes in kidney function biomarkers, including estimated glomerular filtration rate by serum creatinine (GFRscr) or cystatin C (GFRcys), blood urea nitrogen (BUN), and uric acid (UA). Results. For a 10 μg/m3 reduction in PM2.5, a significant improvement was observed for multiple kidney functional biomarkers, including GFRscr, BUN and UA, with a change of 0.42 (95% confidence interval [CI]: 0.06, 0.78) mL/min/1.73m2, -0.38 (-0.64, -0.12) mg/dL, and -0.06 (-0.12, -0.00) mg/dL, respectively. A lower socioeconomic status, indicated by rural residence or low educational level, enhanced the adverse effect of PM2.5 on kidney function. Conclusions. These results support a significant nephrotoxicity of PM2.5 based on multiple serum biomarkers and indicate a beneficial effect of improved air quality on kidney function.

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“…PM2.5 has become the primary urban space pollution problem in China and seriously threatens human health (Bonyadi et al 2016;Li et al 2021) and hinders urban operation through the formation of haze.…”

Section: Introductionmentioning

confidence: 99%

Influence of the Spatial Distribution Pattern of Buildings on the Distribution of PM2.5 Concentration

Zhang

Shan

Lin

et al. 2021

Preprint

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The spatial distribution pattern of buildings is an entry point for controlling the diffusion of pollution particles at an urban spatial structure scale. In this study, we adopted ordinary kriging interpolation and other methods to study the spatial distribution pattern of PM2.5 and constructed urban spatial structure indexes based on building distribution patterns to reveal the influence of building spatial distribution patterns on PM2.5 concentration across the study area and at different elevations. The present study suggests that: (1) Topographic elevation is an important factor influencing the distribution of PM2.5; the correlation coefficient reaches −0.761 and exceeds the 0.001 confidence level. As the elevation increases, the urban spatial structure indexes show significant correlations with PM2.5, and the regularity becomes stronger. (2) The PM2.5 concentration is negatively correlated with the mean and standard deviation of the DEM, the mean and maximum absolute building height, the outdoor activity area, and the average distance between adjacent buildings; and is positively correlated with the sum of the building base area, the building coverage ratio, the space area, the building coverage ratio, the space occupation ratio, and the sum of the building volume. These urban spatial structure indexes are important factors affecting PM2.5 concentration and distribution and should be considered in urban planning. (3) Spatio-temporal differences in PM2.5 concentration and distribution were found at different elevation and time ranges. Indexes, such as the average building height, the average building base area, the sum of the building volume, and the standard deviation of building volume experienced significant changes. Higher PM2.5 concentration yielded a more significant influence of urban spatial structure indexes on PM2.5 distribution. More discrete spatial distributions of PM2.5 yielded weaker correlations between PM2.5 concentrations and the urban spatial structure indexes.

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Association of long-term exposure to PM2.5 with blood lipids in the Chinese population: Findings from a longitudinal quasi-experiment

Cited by 46 publications

References 38 publications

Overview of particulate air pollution and human health in China: Evidence, challenges, and opportunities

Overview of particulate air pollution and human health in China: Evidence, challenges, and opportunities

Association of PM _2.5 Reduction with Improved Kidney Function: A Nationwide Quasiexperiment among Chinese Adults

Influence of the Spatial Distribution Pattern of Buildings on the Distribution of PM2.5 Concentration

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Association of long-term exposure to PM2.5 with blood lipids in the Chinese population: Findings from a longitudinal quasi-experiment

Cited by 46 publications

References 38 publications

Overview of particulate air pollution and human health in China: Evidence, challenges, and opportunities

Overview of particulate air pollution and human health in China: Evidence, challenges, and opportunities

Association of PM 2.5 Reduction with Improved Kidney Function: A Nationwide Quasiexperiment among Chinese Adults

Influence of the Spatial Distribution Pattern of Buildings on the Distribution of PM2.5 Concentration

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Association of PM _2.5 Reduction with Improved Kidney Function: A Nationwide Quasiexperiment among Chinese Adults