Association of Insulin-like Growth Factor-II Apa1 and MspI Polymorphisms with Intrauterine Growth Restriction Risk

Karimi-Zarchi, Mojgan; Zanbagh, Leila; Javaheri, Atiyeh; Tabatabaei, Razieh Sadat; Abbasi, Hajar; Meibodi, Bahare; Hadadan, Amaneh; Bahrami, Reza; Mirjalili, Seyed Reza; Neámatzadeh, Hossein

doi:10.1080/15513815.2020.1745970

Cited by 33 publications

(3 citation statements)

References 29 publications

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“…According to the available data, the type of delivery, vaginal or cesarean, has no effect on the viral transmission (Karimi-Zarchi et al, 2020;Ryan et al, 2020). Moreover, there is no evidence that COVID-19 can cause congenital abnormalities or miscarriages (ECDC, 2020).…”

Section: Pregnancy and Covid-19mentioning

confidence: 99%

COVID-19 Genetic and Environmental Risk Factors: A Look at the Evidence

et al. 2020

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The Covid-19 pandemic is with no doubt the biggest health crisis of the 21 st century. The disease is caused by a virus of the Coronaviridae family and is closely related to the virus responsible for the severe acute respiratory Syndrome (SARS). Since December 2019, the virus has continued to spread way beyond the location of the first recorded cases (Wuhan, China). As of now, over 5 million cases have been diagnosed with the disease worldwide and over 300 thousand have died. COVID-19 patients suffer from respiratory symptoms that can rapidly turn into potentially fatal acute respiratory distress syndrome (ARDS) in a portion of patients. Although many drugs and vaccines are currently under clinical trials, there is no currently approved treatment or vaccine. It is therefore critical to correctly identify risk factors that lead to the exacerbation of symptoms in highly susceptible groups. Groups that are at high risk include those aged 55 or older especially those with underlying conditions such as cardiovascular diseases. Certain ethnicities such as African-Americans have been found to be at a higher risk and males seem to be higher both in numbers as well as severity of cases. It is hypothesized that these groups are at risk as their molecular landscape is more permissive of viral infection and growth. Different occupations, especially those related to health-care as well as populations that do not cultivate a mask-wearing culture are at higher risk due to environmental exposure. In this article, we examine the evidence regarding different groups that are more sensitive to the disease and review hypotheses pertaining to COVID-19 infection and prognosis. Risk factors that can be related to the molecular landscape of COVID-19 infection as well as those related to environmental and occupational conditions are discussed.

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Section: Pregnancy and Covid-19mentioning

confidence: 99%

COVID-19 Genetic and Environmental Risk Factors: A Look at the Evidence

et al. 2020

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“…There are studies which reported that there was no vertical transmission of infection. 32 However, as per a recent report by Dong et al, it has been noted that a neonate born to a 28-year-old primigravida who was a confirmed case of COVID-19, was tested for COVID-19 IgG and IgM antibodies at 2 hours of age. The IgM level was 45.83 AU/mL and the IgG level was 140.32 AU/mL.…”

Section: Vertical Transmissionmentioning

confidence: 98%

Coronavirus Disease-2019 and More: The Story of Coronaviruses So Far

Bhavana¹,

Amarnath²,

Amarnath³

2020

Pediatric Infectious Disease

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Coronaviruses are not new to the human population. These enveloped ribonucleic acid (RNA) viruses have been the cause for various respiratory and gastrointestinal infections. They have caused serious epidemics of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) earlier. Now, we are battling the current pandemic coronavirus disease-2019 . Though this novel virus has relatively low fatality, it has engulfed the word due to its high infectivity. This review is an attempt to take you through the story of coronaviruses so far, highlighting their virology, evolution, and spectrum of diseases. We have reviewed the effects of COVID-19 on pregnancy, newborns and children, testing and preventive strategies, herd immunity, and the way forward in this ongoing battle.

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“…They revealed that PPARγ SNP was positively correlated and FTO SNP negatively correlated with FGR, and these effects were gender specific [ 31 ]. Karimi-Zarchi et al suggested that the Apa1 polymorphism of insulin growth factor 2 (IGF-2) is associated with an increased risk of FGR [ 32 ]. Additionally, epigenetic changes, including i.a.…”

Section: Fetal Fgr Causesmentioning

confidence: 99%

Genetic Background of Fetal Growth Restriction

Nowakowska¹,

Pankiewicz²,

Nowacka³

et al. 2021

IJMS

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Fetal growth restriction (FGR) is one of the most formidable challenges in present-day antenatal care. Pathological fetal growth is a well-known factor of not only in utero demise in the third trimester, but also postnatal morbidity and unfavorable developmental outcomes, including long-term sequalae such as metabolic diseases, diabetic mellitus or hypertension. In this review, the authors present the current state of knowledge about the genetic disturbances responsible for FGR diagnosis, divided into fetal, placental and maternal causes (including preeclampsia), as well as their impact on prenatal diagnostics, with particular attention on chromosomal microarray (CMA) and noninvasive prenatal testing technique (NIPT).

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Association of Insulin-like Growth Factor-II Apa1 and MspI Polymorphisms with Intrauterine Growth Restriction Risk

Cited by 33 publications

References 29 publications

COVID-19 Genetic and Environmental Risk Factors: A Look at the Evidence

COVID-19 Genetic and Environmental Risk Factors: A Look at the Evidence

Coronavirus Disease-2019 and More: The Story of Coronaviruses So Far

Genetic Background of Fetal Growth Restriction

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