Association of H. pylori Infection with Insulin Resistance and Metabolic Syndrome Among Lebanese Adults

Abstract

Prevalence of H. pylori infection in Lebanon is comparable to other developing countries. Furthermore, our findings suggested no association of H. pylori infection with IR or MetS. Eradication of H. pylori infection to prevent IR or MetS is not warranted.

Epidemiology of Helicobacter pylori Infection among Symptomatic Patients, Correlation with Endoscopic Findings and it’s Association with Type II Diabetes Mellitus

“…This number is in line with the three previously conducted studies in Lebanon that estimated the prevalence between 21% and 52% [13][14][15]. In our study we found no difference in H. pylori prevalence between the sexes.…”

“…In our study we found no significant association between H. pylori and diabetes (p=0.979). This is in line with a study done by Naja et al on the association of H. pylori infection with insulin resistance and metabolic syndrome (MetS) among Lebanese adults that found no association of H. pylori infection with IR or MetS, and concluded that the eradication of H. pylori infection to prevent IR or MetS is not warranted [15].…”

“…Zelenkova had reported a prevalence of H. pylori to be lower in diabetics compared to non-diabetic controls (27% vs. 51%) [27,28]. In other studies, the prevalence of H. pylori infection was comparable between diabetic and control [10][11][12][13][14][15][16][17]. In our study we found no significant association between H. pylori and diabetes (p=0.979).…”

“…Since, in the current literature, there is no comprehensive review representing an evidence-based knowledge on the prevalence of H. Pylori infection and its potential associations with dyspeptic symptoms in the Middle Eastern countries [12][13][14][15][16] and in Lebanon [17][18][19]; and on the association of H. pylori and diabetes mellitus [19] we conducted this study aiming to determine the prevalence of H. pylori infection by using gastric biopsy detection in symptomatic patients, to examine potential risk factors that may influence the acquisition of H. pylori infection, and its possible association with diabetes.…”

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“…Multiple animal and human studies were performed over the years in order to understand the links between Hp and T2DM [15][16][17].…”