Association of hematocrit with blood pressure and hypertension

Emamian, Marzieh; Hasanian, Seyed Mahdi; Tayefi, Maryam; Bijari, Moniba; far, Faeze Movahedian; Shafiee, Mojtaba; Avan, Amir; Heidari‐Bakavoli, Alireza; Moohebati, Mohsen; Ebrahimi, Mahmoud; Darroudi, Sousan; Zamani, Parvin; Azarpazhooh, Mahmoud Reza; Nematy, Mohsen; Safarian, Mohammad; Ferns, Gordon A.; Esmaeili, Habibollah; Parizadeh, Mohammad Reza

doi:10.1002/jcla.22124

Cited by 62 publications

(53 citation statements)

References 47 publications

(54 reference statements)

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“…There was a significant relationship between serum UA level and hs‐CRP in these patients, suggesting the role of inflammation in HTN process. The possible interaction between blood viscosity, inflammation, and UA, which in conjunction with high BP may have an adverse impact on endothelial function and so become a risk factors for future events, which is in line with previous observation. In particular, Puddu et al explored the association of serum UA with the incidence of coronary and cardiovascular events in an Italian population.…”

Section: Discussionsupporting

confidence: 69%

“…In particular, Puddu et al explored the association of serum UA with the incidence of coronary and cardiovascular events in an Italian population. They showed that increased serum UA levels and RBC was independently related with risk of CVD events in the 6‐year follow‐up of the Gubbio Study . Another study by this research group also showed the value of serum UA as a predictor of long‐term incidence of cardiovascular events and deaths .…”

Section: Discussionmentioning

confidence: 87%

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Relationship between platelet count and platelet width distribution and serum uric acid concentrations in patients with untreated essential hypertension

et al. 2018

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Section: Discussionsupporting

confidence: 69%

Section: Discussionmentioning

confidence: 87%

Relationship between platelet count and platelet width distribution and serum uric acid concentrations in patients with untreated essential hypertension

et al. 2018

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“…In this regard, Emamian and associates studied 9,808 individuals with essential hypertension and found that they had spurious elevations in their hematocrits, hemoglobin levels, red cell counts, and mean corpuscular hemoglobin values [6]. Their finding is in keeping with the fact that plasma volumes A complete blood count revealed elevations in her hematocrit (packed cell volume, PCV), hemoglobin, and red blood cell count (Table 1).…”

Section: Discussionsupporting

confidence: 39%

Gaisbock's Syndrome: A Case Study

Smith¹

2017

Clin Med Rev Case Rep

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A 57-year-old hypertensive, obese woman presented with several weeks of a febrile flu-like illness, facial and extremity flushing, and laboratory findings of polycythemia. A workup revealed no evidence of polycythemia rubra vera or a secondary cause of her polycythemia (her erythropoietin level was normal, she had no splenomegaly, and a test for JAK2 v617F mutation was negative). Over the next two weeks, her fever subsided, and her hematological profile returned to normal, pre-illness levels. We conclude that this patient had Gaisbock's syndrome, a relative polycythemia that occurs when there is clinically evident contraction of the intravascular fluid space (plasma volume). KeywordsPolycythemia, Hypertension, Plasma volume, Packed cell volume, Venesection, Erythromelalgia resolved over a two-week period as she recovered from her illness. Studies for primary and secondary causes of polycythemia were negative, supporting the diagnosis of Gaisbock's syndrome. Case ReportThe patient, a 57-year-old Caucasian woman, was seen because of a two-week history of fever and a flu-like illness. Her illness began with mild upper airway symptoms (coryza, sore throat), accompanied by myalgias, arthralgias, malaise, fatigue, and anorexia followed by an intermittent non-productive cough and exacerbation of her migraine headaches. She also noted the occurrence of flushing of her face and swelling and flushing of the soles of her feet. Her past medical history was notable for hypertension, a multinodular thyroid, and mild IgM deficiency. She was taking hydrochlorothiazide and triamterene for her hypertension, but was on no other medications. She was a non-smoker, had no history of sleep apnea, and kept herself well hydrated during the illness. Her husband had experienced a flu-like illness 2-3 weeks earlier, and she had recently been immunized to influenza, but the vaccine did not cover 40% of the prevalent strains.Physical examination revealed a temperature of 102 °F, a blood pressure of 138/100, a regular pulse of 74 beats/minute, a respiratory rate of 14 breaths/minute, and a BMI of 41. Facial flushing, which increased in the recumbent position, was present, and the soles of both feet had increased warmth, diaphoresis, and erythema characteristic of erythromelalgia (Figure 1). Her oropharynx was mildly injected without exudates. She had no adenopathy, and the examination of her heart, lungs, and abdomen was unremarkable. Her skin turgor was normal. CASE STUDY

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“…In the MASHAD study, biochemical parameters (including fasting blood glucose [FBG] and lipid profiles), demographic data (including educational level, gender, and age) and medical history as well as lifestyle information (including smoking habit), anthropometric data (including waist circumference [WC], body mass index [BMI], weight, and height) and physical activity (by Self‐declaration form) were gathered by a nurse interview . The methods of biochemical measurements using an automated analyzer and blood pressure assessments using a standard mercury sphygmomanometer are described elsewhere . Participants with dyslipidemia were defined by lipid profiles, as described previously …”

Section: Methodsmentioning

confidence: 99%

Association between obesity categories with cardiovascular disease and its related risk factors in the MASHAD cohort study population

Ghazizadeh

Mirinezhad

Asadi

et al. 2019

Clinical Laboratory Analysis

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This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. AbstractBackground: Cardiovascular disease (CVD) is a significant cause of morbidity and mortality globally. Obesity is an important CVD risk factor and is increasing in prevalence. Methods:In this study, 3829 men and 5720 women (35-65 years) were enrolled as part of the MASHAD cohort study. Four categories were identified according to body mass index and waist circumference that was defined by the World Health Organization. Logistic regression analysis was used to determine the adjusted odds ratio (OR) for the occurrence of CVD, and Cox regression model was used to evaluate the association of obesity with CVD incidence. Results:We found that the higher risk groups defined by categories of adiposity were significantly related to a higher prevalence of a high serum total cholesterol (TC), and triglycerides (TG), and lower high-density lipoprotein cholesterol (HDL), and higher fasting blood glucose (FBG) in both genders and a higher low-density lipoprotein cholesterol (LDL) in women (P < .001). Additionally, a high percentage of participants with dyslipidemia, high LDL, high TC, and low HDL and a high percentage of participants with metabolic syndrome, diabetes, hypertension, and a high serum TG were observed across obesity categories (P < .001). Moreover, women with the very high degrees of obesity had a greater risk of CVD (HR: 1.91, 95% CI: 1.06-3.43, P = .03). Conclusion:Obesity strongly predicts several CVD risk factors. Following 6 years of follow-up, in individuals within increasing degrees of obesity, there was a corresponding significant increase in CVD events, rising to approximately a twofold higher risk of cardiovascular events in women compared with men.

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Association of hematocrit with blood pressure and hypertension

Abstract: We demonstrated the association of altered biochemical and hematological factors with hypertension supporting the value of emerging markers for early prediction of high blood pressure in prone individuals.

Cited by 62 publications

References 47 publications

Relationship between platelet count and platelet width distribution and serum uric acid concentrations in patients with untreated essential hypertension

Relationship between platelet count and platelet width distribution and serum uric acid concentrations in patients with untreated essential hypertension

Gaisbock's Syndrome: A Case Study

Association between obesity categories with cardiovascular disease and its related risk factors in the MASHAD cohort study population

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