Association of Heartburn and Laryngopharyngeal Symptoms with Endoscopic Reflux Esophagitis, Smoking, and Drinking

Lin, Changchun; Wang, Yayu; Wang, Kaili; Lien, Han‐Chung; Liang, Ming-Tai; Yen, Ting-Ting; Wang, Jingping; Liu, Shi-An; Wang, Chen‐Chi

doi:10.1016/j.otohns.2009.05.017

Cited by 21 publications

(32 citation statements)

References 15 publications

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“…Age and sex (male) also may be risk factors. Rosaida and Goh reported that independent risk factors for reflux esophagitis were male gender, Indian race, presence of hiatal hernia, and alcohol consumption [17] The mean RSI score pre treatment was 17.3 ± 2.5SD and post treatment it was 6.5 ± 2.22 SD (p <0.01). All the patients were relieved of the symptoms after 2mths.…”

Section: Discussionmentioning

confidence: 94%

Hoarseness and Laryngopharyngeal Reflux: A Prospective Study

Pullarat¹

2017

IOSR JDMS

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Section: Discussionmentioning

confidence: 94%

Hoarseness and Laryngopharyngeal Reflux: A Prospective Study

Pullarat¹

2017

IOSR JDMS

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“…This was because quit smoking might improve the nicotine-induced decline in esophageal lower sphincter pressure, which had led to frequent occurrence period of time in this study. Chang-Chun Lin et al [21] and Belafsky P.C. et al [22] pointed out in their studies using RSI (reflux symptom indexes) scores that smoking provoked symptoms related to the vocal cord or the laryngopharynx.…”

Section: Discussionmentioning

confidence: 99%

Quit smoking improves gastroesophageal reflux symptoms and quality of life

Nakajima¹,

Nagahara²,

Kurosawa³

et al. 2011

Health

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Background: Smoking is considered to be risk factors of gastroesophageal reflux disease (GERD). The present study aimed to reveal whether quit smoking improves GERD symptoms and QOL of patients. Methods: In this prospective study, 33 patients who participated in a 12-week quit smoking program filled out the Frequency Scale for the Symptoms of GERD (FSSG) questionnaire, and SF8 QOL questionnaire. Patients filled out the questionnaires at baseline and during the program at 2 weeks, 4 weeks, 8 weeks and 12 weeks. In the FSSG, the responses were scored and the reflux score (RS), dysmotility score (DS) and total score (TS) were calculated. Results: There were 22 males and 11 females. Their mean age was 54.8 ± 13.0 (mean ± SD) yr, BMI was 22.9 ± 4.0, and duration of smoking was 33.5 ± 12.5 years. Ten patients belonged to GERD subgroup (baselineFSSGscore ≥ 8). All patients were successful at quit smoking. Scores of TS/RS/DS are 8.6 ± 1.8 (mean ± SE)/4.2 ± 0.9/4.5 ± 0.9 at baseline, 4

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“…Symptoms are important diagnostic clues to acid reflux disorders [12]. Although acid reflux is a common etiologic factor, the signs and symptoms of disease vary considerably between GERD and LPR.…”

Section: Discussionmentioning

confidence: 99%

“…But, the relationship between GERD and extraesophageal symptoms has not been definitively established [13]. The extraesophageal symptoms might come from direct acid injury to the laryngopharynx or vagovagal reflexes triggered by the esophageal or tracheal mucosa [12].…”

Section: Discussionmentioning

confidence: 99%

Comparative outcomes of antireflux treatment for laryngopharyngeal reflux symptoms and upper abdominal symptoms in patients with endoscopic esophagitis

Toros¹,

Toros

Özel

et al. 2010

Eur Arch Otorhinolaryngol

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The objectives of this prospective study are to determine the prevalence of laryngopharyngeal reflux (LPR) symptoms in patients with endoscopic esophagitis, to investigate the relationship between LPR symptoms and upper abdominal symptoms of gastroesophageal reflux disease (GERD) and to compare the treatment responses of both symptom groups. 120 consecutive patients having complaints of GERD were included. Group I consisted of 62 patients with a diagnosis of endoscopic esophagitis. The second group consisted of 58 subjects with no detectable pathology at gastroscopy. LPR symptoms and upper abdominal symptoms were graded. Proton pump inhibitors (PPI) were prescribed to patients. Both groups of symptoms were compared in two groups of patients. The improvement in symptoms was evaluated after treatment. The frequencies of LPR symptoms were statistically higher in patients with endoscopic esophagitis. All LPR symptoms were statistically relieved in their frequency after treatment. The decrease in LPR symptom scores after treatment in group I was statistically significant. FSSG (frequency scale for the symptoms of GERD) scores were statistically higher in group I than in group II before treatment. After treatment, FSSG scores were significantly decreased in group I. There was statistically significant positive correlation between the LPR symptom scores and FSSG scores before treatment. In conclusion, there is a high incidence of LPR symptoms and upper abdominal symptoms in patients with endoscopic esophagitis. LPR and upper abdominal symptoms responded well to antireflux treatment in patients with endoscopic esophagitis.

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Association of Heartburn and Laryngopharyngeal Symptoms with Endoscopic Reflux Esophagitis, Smoking, and Drinking

Cited by 21 publications

References 15 publications

Hoarseness and Laryngopharyngeal Reflux: A Prospective Study

Hoarseness and Laryngopharyngeal Reflux: A Prospective Study

Quit smoking improves gastroesophageal reflux symptoms and quality of life

Comparative outcomes of antireflux treatment for laryngopharyngeal reflux symptoms and upper abdominal symptoms in patients with endoscopic esophagitis

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