Association of Handgrip Strength and Muscle Mass with Dependency in (Instrumental) Activities of Daily Living in Hospitalized Older Adults -The EMPOWER Study

Meskers, Carel G.M.; Reijnierse, Esmee M.; Numans, Siger T.; Kruizinga, Roeliene C.; Pierik, Vincent D.; Ancum, Jeanine M. Van; Slee-Valentijn, Monique S.; Scheerman, Kira; Verlaan, Sjors; Maier, Andrea B.

doi:10.1007/s12603-019-1170-5

Cited by 40 publications

(27 citation statements)

References 48 publications

(47 reference statements)

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“…Loss of muscle mass could be explained by a variety of different factors including the loss of innervation from alpha‐motor neurons , reduced dietary protein intake , and less physical activity . Individuals with lower muscle mass have more difficulty in performing ADL and IADL . Furthermore, it has been suggested that the infiltration of fat into the muscle is a risk factor for low muscle mass, which is associated with worsening ADL and IADL .…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Muscle mass, strength, and physical performance predicting activities of daily living: a meta‐analysis

Wang

Yao

Zirek

et al. 2019

J cachexia sarcopenia muscle

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360

258

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Background Activities of daily living (ADLs) and instrumental activities of daily living (IADLs) are essential for independent living and are predictors of morbidity and mortality in older populations. Older adults who are dependent in ADLs and IADLs are also more likely to have poor muscle measures defined as low muscle mass, muscle strength, and physical performance, which further limit their ability to perform activities. The aim of this systematic review and meta‐analysis was to determine if muscle measures are predictive of ADL and IADL in older populations. Methods A systematic search was conducted using four databases (MEDLINE, EMBASE, Cochrane, and CINAHL) from date of inception to 7 June 2018. Longitudinal cohorts were included that reported baseline muscle measures defined by muscle mass, muscle strength, and physical performance in conjunction with prospective ADL or IADL in participants aged 65 years and older at follow‐up. Meta‐analyses were conducted using a random effect model. Results Of the 7760 articles screened, 83 articles were included for the systematic review and involved a total of 108 428 (54.8% female) participants with a follow‐up duration ranging from 11 days to 25 years. Low muscle mass was positively associated with ADL dependency in 5/9 articles and 5/5 for IADL dependency. Low muscle strength was associated with ADL dependency in 22/34 articles and IADL dependency in 8/9 articles. Low physical performance was associated with ADL dependency in 37/49 articles and with IADL dependency in 9/11 articles. Forty‐five articles were pooled into the meta‐analyses, 36 reported ADL, 11 reported IADL, and 2 reported ADL and IADL as a composite outcome. Low muscle mass was associated with worsening ADL (pooled odds ratio (95% confidence interval) 3.19 (1.29–7.92)) and worsening IADL (1.28 (1.02–1.61)). Low handgrip strength was associated with both worsening ADL and IADL (1.51 (1.34–1.70); 1.59 (1.04–2.31) respectively). Low scores on the short physical performance battery and gait speed were associated with worsening ADL (3.49 (2.47–4.92); 2.33 (1.58–3.44) respectively) and IADL (3.09 (1.06–8.98); 1.93 (1.69–2.21) respectively). Low one leg balance (2.74 (1.31–5.72)), timed up and go (3.41 (1.86–6.28)), and chair stand test time (1.90 (1.63–2.21)) were associated with worsening ADL. Conclusions Muscle measures at baseline are predictors of future ADL and IADL dependence in the older adult population.

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Section: Discussionmentioning

confidence: 99%

“…Individuals with lower muscle mass have more difficulty in performing ADL and IADL 111,112 . Furthermore, it has been suggested that the infiltration of fat into the muscle is a risk factor for low muscle mass, which is associated with worsening ADL and IADL 111 .…”

Section: Muscle Massmentioning

confidence: 99%

Muscle mass, strength, and physical performance predicting activities of daily living: a meta‐analysis

Wang

Yao

Zirek

et al. 2019

J cachexia sarcopenia muscle

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360

258

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“…En nuestro estudio, la FA de las jóvenes universitarias se encontró por arriba del p50 de acuerdo a la edad y sexo en concordancia con dos referencias con población adulta Latinoamericana 21,22 . Si bien, los resultados de este estudio muestran que la población tenía una adecuada FA, es necesario identificar de forma temprana estos indicadores para así promover el mantenimiento de un estilo de vida saludable por medio de ejercicio físico y dieta saludable, lo que posibilita que las mujeres jóvenes universitarias preserven su masa muscular, fuerza y funcionalidad en esta etapa de la vida 3,27 . De igual manera, los resultados contribuyen a fomentar la FM como indicador de salud en los sistemas de vigilancia epidemiológica, justificándose claramente durante la etapa universitaria debido a que investigaciones en jóvenes universitarias señalan que una baja FM se relaciona con perfiles metabólicos pobres, obesidad, y dolores músculo esqueléticos, mismos que fomentarían resultados poco favorables en salud en su vida posterior 7,28 .…”

Section: Resultsunclassified

Fuerza de agarre como predictor de composición corporal en estudiantes universitarias

et al. 2020

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RESUMEN La relevancia que tiene la medición de la fuerza de agarre (FA) se ha incrementado en los últimos años como marcador del estado nutricional, por su relación con la morbilidad y mortalidad y por su creciente aplicación clínica y epidemiológica. Estudios de FA en adultos jóvenes sanos, revelan que se asocia positivamente con variables antropométricas y de composición corporal, mismas que se vincularían con la promoción de la salud en esta población. El objetivo de este estudio fue determinar la correlación entre la FA con variables de antropometría, composición corporal medida por bioimpedancia eléctrica y con la realización de ejercicio, para evaluar su utilidad como indicador del estado nutricional en jóvenes universitarias. Los resultados mostraron que en las estudiantes universitarias la FA se correlacionó positiva y significativamente con variables antropométricas (talla), y de composición corporal (masa muscular). Los

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“…Low handgrip strength can possibly cause falls or activities of daily living disability 23 . The handgrip strength is known to correlate with the limb muscle strength, which is available for the evaluation of muscle strength 24 .…”

Section: Discussionmentioning

confidence: 99%

Quantitative Sonographic Assessment of Quadriceps Muscle Thickness for Prospective Fall Injury in Patients Undergoing Maintenance Hemodialysis: an Observational Cohort Study

Sai¹,

Tanaka²,

Ohashi³

et al. 2020

Preprint

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Introduction: Accidental fall risk is high in patients undergoing maintenance hemodialysis. Falls are associated with fatal injury, comorbidities, and mortality. Risk assessment should be conducted as a primary intervention to prevent falls. This study investigated whether quadriceps muscle thickness measured using ultrasonography can prospectively predict fall injury among dialysis patients.Methods: Using an observational cohort study design, 180 ambulatory hemodialysis patients during the period 2015–2016 were recruited in the four dialysis clinics. The sum of the maximum quadriceps muscle thickness on both sides and the average of the maximum thigh circumference and handgrip strength after hemodialysis were calculated. Patients were stratified according to tertiles of quadriceps muscle thickness. Fall injury was surveyed according to the patient’s self-report for the one-year period.Results: Among the 180 hemodialysis patients, 42 (23.3%) had fall injury during the 12-month follow-up period. When the quadriceps muscle thickness levels were stratified into sex-specific tertile, patients in the lowest tertile (men <3.66 cm and women <3.50 cm) were more likely to have higher incidence of fall injury compared with those in the higher two tertiles (0.56 vs. 0.18 and 0.15 fall injuries/person-year). After adjusting for covariates, lower quadriceps muscle thickness was found to be an independent predictor for fall injury (hazard ratio [95% confidence interval], 2.99 [1.46–6.32], P < 0.001). Conversely, no significant differences were found in the thigh circumference and handgrip strength between women with fall injury and those women without fall injury.Conclusions: Quadriceps muscle thickness using ultrasonography can be measured easily at the bedside and is a precise predictor of fall injury in patients undergoing maintenance hemodialysis.

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Association of Handgrip Strength and Muscle Mass with Dependency in (Instrumental) Activities of Daily Living in Hospitalized Older Adults -The EMPOWER Study

Cited by 40 publications

References 48 publications

Muscle mass, strength, and physical performance predicting activities of daily living: a meta‐analysis

Muscle mass, strength, and physical performance predicting activities of daily living: a meta‐analysis

Fuerza de agarre como predictor de composición corporal en estudiantes universitarias

Quantitative Sonographic Assessment of Quadriceps Muscle Thickness for Prospective Fall Injury in Patients Undergoing Maintenance Hemodialysis: an Observational Cohort Study

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