Association of Hand Grip Strength and Cardiometabolic Markers in Korean Adult Population: The Korea National Health and Nutrition Examination Survey 2015-2016

Abstract

See editorial commentary page on 271 Background: Muscle strength has been suggested as a cardiovascular marker. The aim of this study was to examine the associations between hand grip strength and biomarkers of cardiovascular disease in the Korean population. Methods: A total of 9,083 participants aged 20-80 years from Korea National Health and Nutrition Examination Survey 2015-2016 were investigated. Results: Among men, both relative and dominant hand grip strength showed a positive association with diastolic blood pressure in those aged 65-80 years (95% confidence interval, P-value of dominant and relative hand grip strength: β=0.06, 0.01; P<0.05). Among women, relative and dominant hand grip strength showed a positive relationship to diastolic blood pressure in those aged 20-64 years (β=0.06, 0.01; P<0.001). Body mass index was positively associated with dominant hand grip strength in younger women (β=0.18, P<0.05), whereas it was positively associated with relative hand grip strength in all sex and age groups. High-sensitivity C-reactive protein showed a negative association with relative and dominant hand grip strength in all women, although the same association was observed only in younger men. Diabetes was inversely related to hand grip strength in younger women and men. Conclusion: Increased hand grip strength may be associated with lower C-reactive protein in women and with less risk of diabetes in the Korean adult population. Further prospective studies are needed for the determination of causality between cardiometabolic markers and hand grip strength.

Relationship Between Handgrip Strength and the Prevalence of Diabetes Mellitus Among Korean Adults: Korean National Health and Nutrition Examination Survey, 2014-2018

“…악력은 근력을 대표하는 지표 중 하나로써 [15,16], 대사성 질환의 유병 률 및 발병률과 높은 관계성이 있는 것으로 보고되고 있다 [17][18][19][20][21][22][23][24][25] [17,19,21,23] 또는 절대 악력과 관련성이 있음을 제시한다 [20].…”

Grip Strength as a Cardiometabolic Marker

“…15) However, Ho et al, 16) revealed that both the abso-lute and relative grip strengths had similar predictive abilities for cardiovascular disease and all-cause mortality. 16) Using the KNHANES 2015-2016, Chong et al 17) assessed the association between the absolute and relative grip strengths and cardiometabolic outcomes in a Korean adult population stratified by sex and age. Grip strength measurements could be affected by the protocol used.…”

“…Therefore, Chong et al 17) used the Southampton protocol to measure handgrip strength (HGS) following the suggestion of Roberts et al 13) Chong et al 17) revealed that grip strength has a Thus, grip strength could be used as a biomarker of healthy aging for people of all ages and may be an effective screening…”

“…Using the KNHANES 2015–2016, Chong et al [ 17 ] assessed the association between the absolute and relative grip strengths and cardiometabolic outcomes in a Korean adult population stratified by sex and age. Grip strength measurements could be affected by the protocol used.…”

“…After multiple measurements, the grip strength could reduce, and the maximum grip strength may be greater than the mean value of three trials. Therefore, Chong et al [ 17 ] used the Southampton protocol to measure handgrip strength (HGS) following the suggestion of Roberts et al [ 13 ] Chong et al [ 17 ] revealed that grip strength has a negative relationship with BMI, high-sensitivity C-reactive protein (hsCRP), and diabetes, and a positive relationship with physical activity in youths of both sexes. However, there were no significant association between dominant grip strength and BMI, relative grip strength and hsCRP, or relative grip strength and diabetes in elderly persons of both sexes.…”