2023
DOI: 10.3390/ijms24032235
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Association of GILZ with MUC2, TLR2, and TLR4 in Inflammatory Bowel Disease

Abstract: Ulcerative colitis (UC) and Crohn’s Disease (CD) are chronic relapsing inflammatory diseases that are caused by genetic, environmental, and immune factors. Treatment strategies are currently based on symptomatic control by immunosuppression. The glucocorticoid-induced leucine zipper (GILZ), a mediator of several effects of glucocorticoids, was recently found to be secreted by goblet cells and play a role in inflammatory bowel disease (IBD). This study investigates which genes GILZ is associated with in its rol… Show more

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Cited by 9 publications
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