Association of gender with clinical outcomes of patients with acute ST-segment elevation myocardial infarction presenting with acute heart failure

Dharma, Surya; Dakota, Iwan; Andriantoro, Hananto; Firdaus, Isman; Rahma, Salsabila; Siswanto, Bambang Budi

doi:10.1097/mca.0000000000000892

Cited by 6 publications

(6 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another five papers reviewed in detail were excluded after due to data from the same cohorts. A total of 15 studies were finally included in the present systematic review and meta-analysis 10–24…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Contemporary sex differences in mortality among patients with ST-segment elevation myocardial infarction: a systematic review and meta-analysis

Yang

Wang

et al. 2022

BMJ Open

View full text Add to dashboard Cite

ObjectivesTo assess the effect of sex differences on short-term and long-term mortality among patients with ST-segment elevation myocardial infarction (STEMI).DesignSystematic review and meta-analysis of contemporary available evidence.SettingPubMed, Embase and Cochrane Library were searched for relevant studies reporting sex-specific outcomes among patients with STEMI published between 1 January 2010 and 1 August 2020. Risk ratios (RRs) and 95% CIs were measured using DerSimonian and Laird random-effects model. Sensitivity analyses were performed and publication bias was also checked. All statistical analyses were performed using STATA V.15.0.ParticipantsStudies providing data about short-term or long-term mortality stratified by sex in patients with STEMI were included. Only study conducted in last 10 years were included.Primary and secondary outcome measuresThe primary outcome was all-cause death at short-term (in-hospital or 30 days) and long-term (at least 12 months) follow-up.ResultsA total of 15 studies involving 128 585 patients (31 706 (24.7%) female and 96 879 (75.3%) male) were included. In the unadjusted analyses, female were at a higher risk of short-term mortality (RR, 1.73; 95% CI 1.53 to 1.96, p<0.001, I2=77%) but not long-term mortality (RR, 1.23; 95% CI 0.89 to 1.69, p=0.206, I2=77.5%). When adjusted effect estimates from individual studies were used in meta-analysis, the association between female and higher risk of short-term mortality remained significant (RR, 1.24; 95% CI 1.11 to 1.38, p<0.001, I2=39.6%). And adjusted long-term mortality was also similar between female and male (RR, 1.11; 95% CI 0.42 to 1.80, p=0.670, I2=74.5%).ConclusionsAn increased short-term but not long-term mortality was found in female with STEMI. After adjustment for baseline cardiovascular risk factors and clinical profiles, short-term mortality remains higher in female with STEMI compared with male, indicating the need for further improvements in management in female patients.

show abstract

Section: Resultsmentioning

confidence: 99%

“…A total of 15 studies were finally included in the present systematic review and meta-analysis. [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24]…”

Section: Literature Searchmentioning

confidence: 99%

Contemporary sex differences in mortality among patients with ST-segment elevation myocardial infarction: a systematic review and meta-analysis

Yang

Wang

et al. 2022

BMJ Open

View full text Add to dashboard Cite

show abstract

“…Women, especially younger women, have been found to have higher mortality rates from acute myocardial infarction (MI) [14,[105][106][107][108], especially in ST-elevation MI [109]. However, more recent studies show similar mortality outcomes among men and women, both before [110] and after adjusting for risk factors [111][112][113], suggesting that differing CV risk in women may be a driver of perceived mortality differences. Overall CVD mortality in 2016 in women (49.0%) was similar to that in men (51.0%) [1].…”

Section: Outcomes In Women From Racial/ethnic Minority Backgroundsmentioning

confidence: 99%

Disparities in Cardiovascular Care and Outcomes for Women From Racial/Ethnic Minority Backgrounds

Balla

Gomez

Rodríguez

2020

Curr Treat Options Cardio Med

View full text Add to dashboard Cite

Purpose of review Racial, ethnic, and gender disparities in cardiovascular care are well-documented. This review aims to highlight the disparities and impact on a group particularly vulnerable to disparities, women from racial/ethnic minority backgrounds. Recent findings Women from racial/ethnic minority backgrounds remain underrepresented in major cardiovascular trials, limiting the generalizability of cardiovascular research to this population. Certain cardiovascular risk factors are more prevalent in women from racial/ethnic minority backgrounds, including traditional risk factors such as hypertension, obesity, and diabetes. Female-specific risk factors including gestational diabetes and preeclampsia as well as non-traditional psychosocial risk factors like depressive and anxiety disorders, increased child care, and familial and home care responsibility have been shown to increase risk for cardiovascular disease events in women more so than in men, and disproportionately affect women from racial/ethnic minority backgrounds. Despite this, minimal interventions to address differential risk have been proposed. Furthermore, disparities in treatment and outcomes that disadvantage minority women persist. The limited improvement in outcomes over time, especially among non-Hispanic Black women, is an area that requires further research and active interventions. Summary Understanding the lack of representation in cardiovascular trials, differential cardiovascular risk, and disparities in treatment and outcomes among women from racial/ethnic minority backgrounds highlights opportunities for improving cardiovascular care among this particularly vulnerable population.

show abstract

“…Acute myocardial infarction can lead to sudden death, and continuous myocardial ischemia can eventually develop into heart failure [11]. Studies have shown that early reperfusion therapy is the key to the successful treatment of STEMI.…”

Section: Discussionmentioning

confidence: 99%

Effect of COVID-19 outbreak on the treatment time of patients with acute ST-segment elevation myocardial infarction

Shen

Cheng

et al. 2021

The American Journal of Emergency Medicine

View full text Add to dashboard Cite

Objective: To explore the effect of COVID-19 outbreak on the treatment time of patients with ST-segment elevation myocardial infarction (STEMI) in Hangzhou, China. Methods: We retrospectively reviewed the data of STEMI patients admitted to the Hangzhou Chest Pain Center (CPC) during a COVID-19 epidemic period in 2020 (24 cases) and the same period in 2019 (29 cases). General characteristics of the patients were recorded, analyzed, and compared. Moreover, we compared the groups for the time from symptom onset to the first medical contact (SO-to-FMC), time from first medical contact to balloon expansion (FMC-to-B), time from hospital door entry to first balloon expansion (D-to-B), and catheter room activation time. The groups were also compared for postoperative cardiac color Doppler ultrasonographic left ventricular ejection fraction (LVEF),the incidence of major adverse cardiovascular and cerebrovascular events (MACCE),Kaplan-Meier survival curves during the 28 days after the operation. Results: The times of SO-to-FMC, D-to-B, and catheter room activation in the 2020 group were significantly longer than those in the 2019 group (P < 0.05). The cumulative mortality after the surgery in the 2020 group was significantly higher than the 2019 group (P < 0.05). Conclusion: The pre-hospital and in-hospital treatment times of STEMI patients during the COVID-19 epidemic were longer than those before the epidemic. Cumulative mortality was showed in Kaplan-Meier survival curves after the surgery in the 2020 group was significantly different higher than the 2019 group during the 28 days.The diagnosis and treatment process of STEMI patients during an epidemic should be optimized to improve their prognosis.

show abstract

Association of gender with clinical outcomes of patients with acute ST-segment elevation myocardial infarction presenting with acute heart failure

Cited by 6 publications

References 20 publications

Contemporary sex differences in mortality among patients with ST-segment elevation myocardial infarction: a systematic review and meta-analysis

Contemporary sex differences in mortality among patients with ST-segment elevation myocardial infarction: a systematic review and meta-analysis

Disparities in Cardiovascular Care and Outcomes for Women From Racial/Ethnic Minority Backgrounds

Effect of COVID-19 outbreak on the treatment time of patients with acute ST-segment elevation myocardial infarction

Contact Info

Product

Resources

About