Abstract:Introduction: Previous studies have reported that chromium (Cr)-induced epigenetic alterations and DNA methylation play a vital role in the pathogenesis of diseases induced by chromium exposure. Epigenomic analyses have been limited and mainly focused on occupational chromium exposure; their findings are not generalizable to populations with environmental Cr exposure.Methods: We identified the differential methylation of genes and regions to elucidate the mechanisms of toxicity related to environmental chromiu… Show more
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