Association of “Elevated Blood Pressure” and “Stage 1 Hypertension” With Cardiovascular Mortality Among an Asian Population

Talaei, Mohammad; Hosseini, Naeimeh; Koh, Angela S.; Yuan, Jian‐Min; Koh, Woon‐Puay

doi:10.1161/jaha.118.008911

Cited by 24 publications

(20 citation statements)

References 24 publications

(52 reference statements)

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“…The Singapore Chinese Health Study that included 30 636 participants revealed that neither elevated BP nor stage 1 AH was associated with increased risk of CVD mortality compared with normal BP in the whole cohort. Stage 1 AH was related with increased CVD risk only in those <65 years of age and without a history of CVD, but not in those ≥65 years of age or with a history of CVD . Similar results were obtained in the Chinese Multi‐provincial Cohort Study; the Authors showed that stage 1 AH increased CVD risk in young and middle‐aged Chinese adults, but not in those age ≥60 years .…”

Section: Blood Pressure ≥130/80 MM Hg and Cvd Outcomesupporting

confidence: 70%

Should blood pressure ≥130/80 mm Hg be considered as a cardiovascular disease?

Tadić

Cuspidi

2019

J of Clinical Hypertension

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Section: Blood Pressure ≥130/80 MM Hg and Cvd Outcomesupporting

confidence: 70%

Should blood pressure ≥130/80 mm Hg be considered as a cardiovascular disease?

Tadić

Cuspidi

2019

J of Clinical Hypertension

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“…Many countries in Europe or Asia have carefully considered whether the new guideline is suitable for localization across the difference of geographical regions and ethnicities [13][14][15]. A data from the Monitoring of Trends and Determinants in Cardiovascular Disease (MONICA)/Cooperative Health Research in the Region of Augsburg (KORA) cohort study involving 11,603 subjects showed that stage 1 hypertension did not increase the risk of cardiovascular disease (CVD) mortality compared with normal BP [13].…”

Section: Introductionmentioning

confidence: 99%

“…A data from the Monitoring of Trends and Determinants in Cardiovascular Disease (MONICA)/Cooperative Health Research in the Region of Augsburg (KORA) cohort study involving 11,603 subjects showed that stage 1 hypertension did not increase the risk of cardiovascular disease (CVD) mortality compared with normal BP [13]. Similarly, another study demonstrated that the newly defined stage 1 hypertension was not associated with increased risk of CVD mortality among Chinese in Singapore aged 46-85 years [14]. In contrast, stronger associations with subsequent CVD events were observed in those with baseline stage 1 hypertension among Korean young adults [15].…”

Section: Introductionmentioning

confidence: 99%

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The Association of Stage 1 Hypertension Defined by the 2017 ACC/AHA Guideline with Stroke and Its Subtypes among Elderly Chinese

Gao

Dai

Xie

et al. 2020

BioMed Research International

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Background. The 2017 American College of Cardiology and American Heart Association hypertension guideline updated stage 1 hypertension definition as systolic blood pressure range from 130 to 139 mmHg or diastolic blood pressure from 80 to 89 mmHg. However, the association of stage 1 hypertension with stroke and its subtypes among the older population in rural China remains unclear. Methods. This population-based cohort study consisted of 7,503 adults aged ≥60 years with complete data and no cardiovascular disease at baseline from rural areas of Fuxin County, Liaoning province, China. Follow-up for the new cases of stroke was conducted from the end of the baseline survey to the end of the third follow-up survey (January 1, 2007–December 31, 2017). Adjusted Cox proportional hazards models were used to estimate hazard ratios and 95% confidence intervals with the normal blood pressure as a reference, and calculated population attributable risk was based on prevalence and hazard ratios. Results. During a median follow-up of 12.5 years, we observed 1,159 first-ever incident stroke (774 ischemic, 360 hemorrhagic, and 25 uncategorized). With the blood pressure <120/<80 mmHg as a reference, stage 1 hypertension showed the adjusted hazard ratios (95% confidence intervals) of 1.45 (1.11–1.90) for all stroke, 1.65 (1.17–2.33) for ischemic stroke, and 1.17 (0.74–1.85) for hemorrhagic stroke, respectively. In this study, the population attributable risk values of stage 1 hypertension were 10.22% (2.64%–18.56%) for all stroke and 14.34% (4.23%–25.41%) for ischemic stroke. Conclusion. Among adults aged ≥60 years in rural China, stage 1 hypertension defined by 2017 American College of Cardiology and American Heart Association hypertension guideline was independently associated with the increased risk of all stroke and ischemic stroke, excluding hemorrhagic stroke.

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“…Qi Y et al demonstrated that stage 1 hypertension increased the risk of cardiovascular events in young and middle‐aged adults, but not in those aged ≥60 years. In addition, Mohammad Talaei, et al indicated that stage 1 hypertension was associated with increased cardiovascular risk only in those <65 years of age and without a history of CVD (hazard ratio [HR], 1.40; 95% confidence interval [CI], 1.01‐1.94), excluding those ≥65 years of age or with a history of CVD. These authors also claimed that further validation of their results using a larger sample size of older people is still required.…”

Section: Introductionmentioning

confidence: 99%

Stage 1 hypertension defined by the 2017 ACC/AHA guideline predicts future cardiovascular events in elderly Chinese individuals

Xie

Gao

Guo

et al. 2019

J of Clinical Hypertension

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The 2017 American College of Cardiology and American Heart Association (ACC/AHA) hypertension guideline updated stage 1 hypertension defined as systolic blood pressure (SBP) of 130‐139 mm Hg or diastolic blood pressure (DBP) of 80‐89 mm Hg. However, the impact of 1 hypertension that affects future cardiovascular risk remains unclear among older adults in rural China. The prospective cohort study included 7503 adults aged ≥60 years with complete data and no cardiovascular disease (CVD) at baseline. Follow‐up for the new adverse events was conducted from the end of the baseline survey to the end of the third follow‐up survey (2007.01‐2017.12). Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs) for blood pressure (BP) classifications and adverse events with normal BP as reference (< 120/80 mm Hg). During the 57 290 person‐years follow‐up period, 2261 all‐cause mortality, 1271 CVD mortality, 1159 stroke, and 347 myocardial infarctions (MI) occurred. Patients with stage 1 hypertension versus normal BP had HRs (95% CI) of 1.068 (0.904‐1.261) for all‐cause mortality, 1.304 (1.015‐1.675) for CVD mortality, 1.449 (1.107‐1.899) for stroke, and 1.735 (1.051‐2.863) for MI, respectively. In conclusion, among adults aged ≥60 years, stage 1 hypertension revealed an increased hazard of CVD mortality, stroke, and MI, which is complementary evidence for the application of 2017 ACC/AHA hypertension guidelines in an older Chinese population. Therefore, BP control in patients with stage 1 hypertension may be beneficial to reduce the hazard of CVD in elderly Chinese individuals.

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Association of “Elevated Blood Pressure” and “Stage 1 Hypertension” With Cardiovascular Mortality Among an Asian Population

Cited by 24 publications

References 24 publications

Should blood pressure ≥130/80 mm Hg be considered as a cardiovascular disease?

Should blood pressure ≥130/80 mm Hg be considered as a cardiovascular disease?

The Association of Stage 1 Hypertension Defined by the 2017 ACC/AHA Guideline with Stroke and Its Subtypes among Elderly Chinese

Stage 1 hypertension defined by the 2017 ACC/AHA guideline predicts future cardiovascular events in elderly Chinese individuals

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