Association of electrocardiographic left and right ventricular hypertrophy with physical fitness of military males: The CHIEF study

Chao, Wei-Hsiung; Su, Fang-Ying; Lin, Felicia; Yu, Yun-Shun; Lin, Gen‐Min

doi:10.1080/17461391.2019.1595741

Cited by 31 publications

(15 citation statements)

References 26 publications

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“…Blood biochemical tests for concentrations of triglycerides, total cholesterol, high-density lipoprotein, fasting glucose, and AST and ALT were enzymatically measured on an auto analyzer (AU640, Olympus, Kobe, Japan). All blood samples were collected by several experienced technicians at the same blood drawing station after an overnight 12-h fast for the participants [ 25 , 26 , 27 , 28 , 29 , 30 ].…”

Section: Methodsmentioning

confidence: 99%

Association of Liver Transaminase Levels and Long-Term Blood Pressure Variability in Military Young Males: The CHIEF Study

Liu

Lin

Chen

et al. 2020

IJERPH

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Background: An inverse relationship of serum liver transaminases and mortality might be due to better blood pressure control in hypertensive patients. Whether it holds true regarding such an association for long-term blood pressure variability (BPV) in those without antihypertensive therapy is unclear. Methods: A population of 1112 military males without antihypertensive medications, aged 32 years, was collected from a retrospective longitudinal study in Taiwan. Serum liver aspartate and alanine transaminase (AST and ALT) levels were obtained from a 12 h-fast blood sample of each participant. BPV was assessed by standard deviation (SD) and average real variability (ARV) of systolic and diastolic blood pressure (SBP and DBP), respectively across 4 visits during the study period (2012–2014, 2014–2015, 2015–2016, and 2016–2018). Multivariable linear regression analysis was utilized to determine the association adjusting for demographics, anthropometric indexes, SBP, DBP, and lipid profiles. Results: In the unadjusted model, ALT was significantly and positively correlated with SDDBP and ARVDBP (β (standard errors) = 0.36 (0.16) and 0.24 (0.12), respectively), and so was AST (β = 0.19 (0.08) and 0.14 (0.06), respectively). All the associations were insignificant with adjustments. However, ALT was significantly and negatively correlated with SDSBP and ARVSBP (β = −0.35 (0.14) and −0.25 (0.11), respectively) and so was AST (β = −0.14 (0.07) and −0.12 (0.06), respectively) with adjustments. Conclusion: Our findings suggested that serum liver transaminases were negatively correlated with long-term systolic BPV in young male adults without antihypertensive therapy, and the clinical relevance needs further investigations.

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Section: Methodsmentioning

confidence: 99%

Association of Liver Transaminase Levels and Long-Term Blood Pressure Variability in Military Young Males: The CHIEF Study

Liu

Lin

Chen

et al. 2020

IJERPH

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“…e retrospective cohort was obtained from the Cardiorespiratory Fitness and Hospitalization Events in Armed Forces (CHIEF) study during 2014 [16][17][18][19][20][21].…”

Section: Study Populationmentioning

confidence: 99%

Association of Tobacco Smoking with Physical Fitness of Military Males in Taiwan: The CHIEF Study

Wang

et al. 2020

Canadian Respiratory Journal

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Tobacco smoking has been found associated with lower cardiorespiratory fitness in white and black males; however, few studies have not been conducted to clarify such relationship in Asian males. We performed a cross-sectional study to investigate the association between tobacco smoking status and physical fitness in 3,669 military males, averaged 29.4 years of age, from the cardiorespiratory fitness and hospitalization events in armed forces (CHIEF) study in Taiwan during 2014. There were 1,376 current smokers, and the others were noncurrent smokers. The effective sample size estimated was 1,230 participants, as the margin of error was ±3% at the 99% confidence level. Physical fitness was evaluated by time for a 3000-meter run test (aerobic fitness) and repetitive numbers of 2-minute sit-ups and 2-minute push-ups (anaerobic fitness) where all procedures were standardized by using computerized scoring systems. A multiple linear analysis adjusting for age, service specialty, body mass index, heart rate, alcohol intake, and training frequency was used to determine the relationship. As compared with noncurrent smoking, current smoking was inversely correlated with longer time for a 3000-meter run (β = 15.66 (95% confidence intervals (CI): 10.62, 20.70)) and fewer repetitive numbers of 2-minute sit-ups and 2-minute push-ups (β = −1.53 (95% CI: −2.08, −0.97) and −1.31 (95% CI: −2.12, −0.50), respectively). Our finding reconfirms the concept that tobacco smoking might reduce both aerobic and anaerobic fitness among young Asian males.

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“…After the health examination, all participants took at least one of the three exercise tests including 2-min sit-ups, 2-mininute push-ups, and a 3000-m run at the Hualien Military Physical Training and Testing Center. The study design of CHIEF study has been described in detail previously [19,[21][22][23][24][25]. In 2014, there were 4080 participants receiving the health examination and exercise tests in the study.…”

Section: Study Populationmentioning

confidence: 99%

Association of Single Measurement of dipstick proteinuria with physical performance of military males: the CHIEF study

et al. 2020

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Background: Proteinuria, a marker of kidney injury, may be related to skeletal muscle loss. Whether the severity of proteinuria is associated with physical performance is unclear. Methods: We examined the association of proteinuria severity with physical performance cross-sectionally in 3357 military young males, free of chronic kidney disease, from the cardiorespiratory fitness and hospitalization events in armed Forces (CHIEF) study in Taiwan. The grades of proteinuria were classified according to one dipstick urinalysis which were collected at morning after an 8-h fast as unremarkable (0, +/−, and 1+), moderate (2+) and severe (3+ and 4+). Aerobic physical performance was evaluated by time for a 3000-m run and anaerobic physical performance was evaluated by numbers of 2-min sit-ups and 2-min push-ups, separately. Multiple linear regressions were used to determine the relationship. Results: As compared with unremarkable proteinuria, moderate and severe proteinuria were dose-dependently correlated with 3000-m running time (β: 4.74 (95% confidence intervals (CI): − 0.55, 10.02) and 7.63 (95% CI: 3.21, 12.05), respectively), and inversely with numbers of 2-min push-ups (β = − 1.13 (− 1.97, − 0.29), and − 1.00 (− 1.71, − 0.28), respectively) with adjustments for age, service specialty, body mass index, blood pressure, alcohol intake, smoking, fasting plasma glucose, blood urea nitrogen, serum creatinine and physical activity. However, there was no association between proteinuria severity and 2-min sit-ups. Conclusions: Our findings show a relationship of dipstick proteinuria with aerobic physical performance and parts of anaerobic physical performance in military healthy males. This mechanism is not fully understood and requires further investigations.

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Association of electrocardiographic left and right ventricular hypertrophy with physical fitness of military males: The CHIEF study

Cited by 31 publications

References 26 publications

Association of Liver Transaminase Levels and Long-Term Blood Pressure Variability in Military Young Males: The CHIEF Study

Association of Liver Transaminase Levels and Long-Term Blood Pressure Variability in Military Young Males: The CHIEF Study

Association of Tobacco Smoking with Physical Fitness of Military Males in Taiwan: The CHIEF Study

Association of Single Measurement of dipstick proteinuria with physical performance of military males: the CHIEF study

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