Association of ED with chronic periodontal disease

Matsumoto, Seiji; Matsuda, Mitsuyoshi; Takekawa, Masanori; Okada, Masuhiko; Hashizume, Kazumi; Wada, Naoki; Hori, Junichi; Tamaki, Gaku; Kita, Masafumi; Iwata, Tatsuya; Κakizaki, Hidehiro

doi:10.1038/ijir.2013.30

Cited by 25 publications

(50 citation statements)

References 16 publications

(25 reference statements)

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“…These primary studies Keller et al, 2012; J. H. Lee et al, 2015;Matsumoto et al, 2014;Oguz et al, 2013;Sharma et al, 2011;Tsao et al, 2015;Uppal et al, 2014;Zadik et al, 2009) were conducted in the following countries: India, Israel, Japan, Korea, Taiwan, and Turkey. Seven studies (Keller et al, 2012;J.…”

Section: Study Selection and Characteristicsmentioning

confidence: 99%

“…All studies Keller et al, 2012; J. H. Lee et al, 2015;Matsumoto et al, 2014;Oguz et al, 2013;Sharma et al, 2011;Tsao et al, 2015;Uppal et al, 2014;Zadik et al, 2009) were performed on humans and under health care or university settings. These primary studies Keller et al, 2012; J. H. Lee et al, 2015;Matsumoto et al, 2014;Oguz et al, 2013;Sharma et al, 2011;Tsao et al, 2015;Uppal et al, 2014;Zadik et al, 2009) were conducted in the following countries: India, Israel, Japan, Korea, Taiwan, and Turkey.…”

Section: Study Selection and Characteristicsmentioning

confidence: 99%

“…Seven studies (Keller et al, 2012;J. H. Lee et al, 2015;Matsumoto et al, 2014;Sharma et al, 2011;Tsao et al, 2015;Uppal et al, 2014;Zadik et al, 2009) had a cross-sectional design. Two studies Oguz et al, 2013) were randomized control trials (RCTs).…”

Section: Study Selection and Characteristicsmentioning

confidence: 99%

“…A limited number of studies Keller, Chung, & Lin, 2012; J. H. Lee et al, 2015;Matsumoto et al, 2014;Oguz et al, 2013;Sharma, Pradeep, & Raju, 2011;Tsao et al, 2015;Uppal, Bhandari, & Singh, 2014;Zadik, Bechor, Galor, Justo, & Heruti, 2009) have identified an association between ED and chronic periodontitis (CP), a disease of the supporting structures of teeth, namely cementum, gingiva, periodontal ligament, and alveolar bone. In the study by Matsumoto et al (2014), an information sheet was distributed to 300 adult men with ED that received a comprehensive dental examination. These results reported a statistically significant association between scores of CP and presence of ED.…”

Section: Introductionmentioning

confidence: 99%

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Association Between Periodontal Disease and Erectile Dysfunction: A Systematic Review

Kellesarian

Malignaggi

et al. 2016

Am J Mens Health

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A limited number of studies have reported an association between erectile dysfunction (ED) and chronic periodontitis (CP). The aim of the present study is to assess the association between CP and ED through a systematic review of published literature. To address the focused question, "Is there a relationship between ED and CP?" indexed databases were searched till December 2015 using various key words "erectile dysfunction," "periodontal disease," "periodontitis," "dental infection," and "impotence." Letters to the editor, commentaries, historic reviews, and experimental studies were excluded. The pattern of the present systematic review was customized to primarily summarize the pertinent data. Nine studies were included. Seven studies had a cross-sectional design and two studies were randomized control trials. The number of study participants ranged between 53 and 513,258 individuals with age ranging between 20 years and 85 years (median age ranging between 34.9 ± 4.9 years and 50.9 ± 16.6 years). In all studies, a positive relationship between CP and ED was reported. In four studies, odds ratio were reported, ranging between 1.53 and 3.35. From the literature reviewed, there seems to be a positive association between ED and CP; however, further well-designed controlled clinical trials are needed in this regard. It is emphasized that physicians should refer patients with ED to oral health care providers for a comprehensive oral evaluation and treatment.

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Section: Study Selection and Characteristicsmentioning

confidence: 99%

Section: Study Selection and Characteristicsmentioning

confidence: 99%

Section: Study Selection and Characteristicsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Association Between Periodontal Disease and Erectile Dysfunction: A Systematic Review

Kellesarian

Malignaggi

et al. 2016

Am J Mens Health

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“…Another study was aimed for investigating the association of CP with the erectile dysfunction (ED) that also supports that CP had a high association with ED in young adults at 30-40 years [5]. Additional independent clinical trial also suggested that dental health is important as a preventive medicine for ED [6].…”

Section: Oral Biologymentioning

confidence: 99%

Periodontal Disease Linked to Erectile Dysfunction

2016

J Oral Biol

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Patients with periodontitis and erectile dysfunction suffer a greater incidence of major adverse cardiovascular events: A prospective study in a Spanish population

Mesa

Arrabal-Polo

Magán‐Fernández

et al. 2022

Journal of Periodontology

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Background: Periodontitis and erectile dysfunction (ED) have been linked with cardiovascular disease. The association of periodontitis and ED with the occurrence of major adverse cardiovascular events has not been previously assessed.The aim of this study was to determine if the presence of periodontitis and ED has any effect on the incidence of major adverse cardiovascular events.Methods: Male patients that attended the Urology service were enrolled in a prospective study. Erectile dysfunction was diagnosed according to the International Index of Erectile Function. Sociodemographic data and periodontal clinical parameters were gathered (pocket probing depth, clinical attachment loss, bleeding on probing (BoP), plaque index and number of teeth) at baseline. Major adverse cardiovascular events occurred both before and during the follow-up time were registered. Bivariate analyses, as well as a multivariate analysis were performed, adjusting for potential confounders. Results: A total of 158 patients were included, with a mean follow-up of 4.2 years.A greater number of major adverse cardiovascular events occurred in the group that presented periodontitis and ED (P = 0.038). After adjusting by age and previous cardiovascular disease in the multivariate analysis, the annual major adverse cardiovascular event rate was estimated to be 3.7 times higher in the same group (P = 0.049). Other periodontal clinical variables together with ED supported these results and were close to statistical significance. Conclusions: Patients with periodontitis and ED, adjusted by age and a cardiovascular disease, showed 3.7 times more risk of suffering major adverse cardiovascular events after mean follow-up of 4.2 years.

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Association of ED with chronic periodontal disease

Cited by 25 publications

References 16 publications

Association Between Periodontal Disease and Erectile Dysfunction: A Systematic Review

Association Between Periodontal Disease and Erectile Dysfunction: A Systematic Review

Periodontal Disease Linked to Erectile Dysfunction

Patients with periodontitis and erectile dysfunction suffer a greater incidence of major adverse cardiovascular events: A prospective study in a Spanish population

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