Association of dietary fat composition with kidney function decline in patients with type 2 diabetes

Novel dietary factors in diabetic and non-diabetic kidney disease

“…Interestingly, in this study, the trend towards a relationship between fat intake and GSI appeared to be largely driven by female mice. In agreement with our findings, one human study has reported an effect of dietary fat consumption on renal function, which was only present in the female population [141], but did not include any histological assessment.…”

“…Consumption of long chain n-3 fatty acids and n-6 fatty acids are associated with a decreased risk of CKD [139,140]. By contrast, excess trans-fat consumption is positively associated with eGFR decline in individuals with T2DM, with this relationship being stronger in women [141].…”