2012
DOI: 10.1001/2012.jama.10779
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Association of Clopidogrel Treatment With Risk of Mortality and Cardiovascular Events Following Myocardial Infarction in Patients With and Without Diabetes

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Cited by 51 publications
(24 citation statements)
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References 30 publications
(24 reference statements)
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“…We classified patients as having diabetes mellitus if they had claimed at least 1 prescription for glucose-lowering medications (A10) within the same time frame. 11,12 The Danish Register of Medicinal Product Statistics does not contain medication dosage but does include information on strengths and number of dispensed tablets and dispensing time interval. On the basis of these data, we calculated the mean daily dosages of loop diuretics (C03CA01) used at the time of surgery as a proxy for HF severity (up to 3 consecutive prescription claims were considered in a retrospective manner).…”
Section: Methodsmentioning
confidence: 99%
“…We classified patients as having diabetes mellitus if they had claimed at least 1 prescription for glucose-lowering medications (A10) within the same time frame. 11,12 The Danish Register of Medicinal Product Statistics does not contain medication dosage but does include information on strengths and number of dispensed tablets and dispensing time interval. On the basis of these data, we calculated the mean daily dosages of loop diuretics (C03CA01) used at the time of surgery as a proxy for HF severity (up to 3 consecutive prescription claims were considered in a retrospective manner).…”
Section: Methodsmentioning
confidence: 99%
“…In addition to ICD-10 codes, use of glucose-lowering agents was used as a proxy for diabetes mellitus and use of loop diuretics as a proxy for heart failure, as done previously (eTable 1 in the Supplement). 23,24 Diagnoses from the National Patient Register included in the Charlson comorbidity index have been validated, with positive predictive values of 96% to 100%. …”
Section: Definition Of Pharmacotherapy Comorbidity and Surgery Riskmentioning
confidence: 99%
“…Major bleeding associated with clopidogrel treatment is treated with multiple infusions of fresh platelets. Because the effects of clopidogrel may be somewhat reduced in patients with diabetes, these patients may benefi t from one of the more potent antiplatelet agents [ 63 ].…”
Section: Clopidogrelmentioning
confidence: 99%