Association of Clinical and Laboratory Variables with In-Hospital Incidence of Deep Vein Thrombosis in Patients with Acute Stroke: A Retrospective Study

Abstract

<jats:title>Abstract</jats:title> <jats:p><jats:bold>Backgrounds: </jats:bold>Deep vein thrombosis (DVT) is a serious complication in patients with acute stroke. Early prediction of DVT could enable physicians to perform a proper prevention strategy. We analyzed the association of clinical and laboratory variables with DVT to evaluate the risk of DVT in patients after stroke.<jats:bold>Results:</jats:bold> Acute stroke patients admitted to the Changsha Central Hospital between January 2016 and December 2019 with length of stay in hospital≥30 d were included. Clinical and laboratory variables for DVT at baseline were collected, and the diagnosis of DVT was confirmed by ultrasonography. Risk factors were developed by Multivariate logistic regression analysis. A total of 101 patients were included in the study, of which 77.2%(78/101) were diagnosed ischemic stroke and 22.8%(23/101)were confirmed hemorrhagic stroke. The overall incidence of DVT after acute stroke within 30 days was 19.8%(20/101). The level of D-dimer when DVT detected was significant increased than that on admission. Pulmonary infection and increased muscle tone as independent relevant factors for DVT were confirmed. <jats:bold>Conclusions</jats:bold>: Pulmonary infection as a risk factor and increased muscle tone as a protector factor for DVT were identified in patients after stroke and the significant change in level of D-dimer could be a warning for DVT occurrence. It helps with taking early managements to reduce the incidence of DVT in patients after stroke.</jats:p>