Association of cannabis use with the development of elevated anxiety symptoms in the general population: a meta-analysis

Twomey, Conal

doi:10.1136/jech-2016-208145

Cited by 51 publications

(30 citation statements)

References 25 publications

(26 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Clinically significant effect sizes were determined a priori: odds ratios (ORs) of 1.5 were considered clinically meaningful differences based on a Cohen of *0.2 24 and previous meta-analyses of cannabis use and mental health outcomes, which used an OR of 1.5 as the cutoff for clinically meaningful effects. 25,26…”

Section: Statistical Analysesmentioning

confidence: 99%

Temporal Changes in the Cross-Sectional Associations between Cannabis Use, Suicidal Ideation, and Depression in a Nationally Representative Sample of Canadian Adults in 2012 Compared to 2002

et al. 2019

View full text Add to dashboard Cite

Background: With the recent legalization of nonmedical cannabis in Canada, it is important to document previous associations between cannabis use and major depressive episode and suicidal ideation, as well as the extent to which these associations have changed over time. Methods: This study uses pooled data from the 2002 and 2012 Canadian Community Health Survey’s Mental Health Component, which are repeated cross-sectional surveys of nationally representative samples of Canadians 15 to 60 years of age (n = 43,466). Binary logistic regression was performed, applying weighting and bootstrapping, to examine the association between at least monthly use of cannabis and past 12-month suicidal ideation and major depressive episode (MDE). Results: At least monthly nonmedical cannabis use was associated with an increased odds of MDE and suicidal ideation, and both associations strengthened in 2012 compared to 2002. Canadians using cannabis at least once a month in 2012 had 1.59 (95% confidence interval [CI], 1.11 to 2.27) times the odds of experiencing suicidal ideation and 1.55 (95% CI, 1.12 to 2.13) times the odds of experiencing MDE compared to those who used cannabis at least once a month in 2002. This temporal change remained after controlling for other substance use. Conclusions: Monthly cannabis use was consistently related to both suicidal ideation and MDE, and these associations were stronger in 2012 compared to 2002. The findings of this study provide a baseline for the association between cannabis use and suicide and depression in the Canadian population that should be reevaluated now that nonmedical cannabis has been legalized.

show abstract

Section: Statistical Analysesmentioning

confidence: 99%

Temporal Changes in the Cross-Sectional Associations between Cannabis Use, Suicidal Ideation, and Depression in a Nationally Representative Sample of Canadian Adults in 2012 Compared to 2002

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Evidence for the predictive role of cannabis consumption on the onset of anxiety disorders is still weak. Recently, two meta-analysis of longitudinal studies ( 51 , 52 ) on the association between cannabis use and anxiety symptoms in the general population concluded that cannabis use is a minor risk factor for the development of elevated anxiety symptoms in the general population. With specific regard to the onset of SA disorder, a recent longitudinal study ( 53 ) assessing the bidirectional association between cannabis use and anxiety disorders in a population-based adult sample found a trend linking problematic cannabis use with the future development of SA.…”

Section: Discussionmentioning

confidence: 99%

Mediating Effects of Global Negative Effect Expectancies on the Association between Problematic Cannabis Use and Social Anxiety

et al. 2017

View full text Add to dashboard Cite

The relationship between social anxiety (SA) and cannabis use among adolescents and young adults is a highly debated topic. In this cross-sectional study, we tested whether cannabis use expectancies mediated the association between SA and cannabis use severity in a sample of 343 young adults (74.3% male) who used cannabis. They completed self-report measures for the screening of problematic cannabis use (Cannabis Use Problems Identification Test) and SA symptoms (Social Interaction Anxiety Scale and Social Phobia Scale). A multiple mediation analysis was used to test whether marijuana effect expectancies mediate SA effect on problematic cannabis use. SA was negatively associated with cannabis use severity in this sample, and we found evidence that cannabis use expectancies fully mediated this relationship. Specifically, global negative effect expectancies influence the relationship between SA and problematic cannabis use. These findings may inform current prevention strategies and clinical intervention for young adults who use cannabis.

show abstract

“…Evidence also supports an increased risk for elevated anxiety symptoms in regular cannabis users. A meta-analysis of 40 studies revealed a 1.15 increased risk of developing elevated anxiety symptoms [91]. On the other hand, individuals with social anxiety disorder are more susceptible to cannabis-related impairment and have an increased risk of developing cannabis use disorder [92,93].…”

Section: Association With Anxiety and Depressionmentioning

confidence: 99%

An overview of the adverse effects of cannabis use for Canadian physicians

Leduc‐Pessah

Jensen²,

Newell

2019

CIM

View full text Add to dashboard Cite

Purpose: Cannabis is the most widely used illicit substance and one of the most commonly used psychoactive substances in the world, preceded only by alcohol, tobacco and caffeine. Recent changes in legislation regarding cannabis use in Canada and potential upcoming changes worldwide may have a further impact on the prevalence of cannabis use. Thus, it is critical to understand the risks and potential adverse health effects of acute and long-term cannabis use. Current literature is lacking in many areas surrounding cannabis use, and for the most part is unable to provide clear associations once confounding variables are considered. Here we provide a general overview of the history of cannabis, the physical and mental health consequences, and the risks to specific groups. Source: A scoping search of published articles in PubMed from the start date (1946) until 2018. Principal finding: Current evidence supports an association between cannabis use and mild respiratory and cardiac effects, but no clear increased risk of cancer. Psychiatric disorders, including schizophrenia and anxiety, show associations with cannabis use; however, a causal effect of cannabis use is unclear. While no evidence for increased risk in pregnancy has been found, risk is still undetermined. Youth may be at a greater risk as earlier initiation of use increases the risk of adverse health effects. Conclusion: Overall, evidence for direct and long-term adverse effects of cannabis use is minimal and additional longitudinal studies will be required to better delineate unidentified effects.

show abstract

Association of cannabis use with the development of elevated anxiety symptoms in the general population: a meta-analysis

Abstract: The findings indicate that cannabis use is no more than a minor risk factor for the development of elevated anxiety symptoms in the general population. They may inform the debate surrounding the legalisation of cannabis.

Cited by 51 publications

References 25 publications

Temporal Changes in the Cross-Sectional Associations between Cannabis Use, Suicidal Ideation, and Depression in a Nationally Representative Sample of Canadian Adults in 2012 Compared to 2002

Temporal Changes in the Cross-Sectional Associations between Cannabis Use, Suicidal Ideation, and Depression in a Nationally Representative Sample of Canadian Adults in 2012 Compared to 2002

Mediating Effects of Global Negative Effect Expectancies on the Association between Problematic Cannabis Use and Social Anxiety

An overview of the adverse effects of cannabis use for Canadian physicians

Contact Info

Product

Resources

About