Association of Behçet’s disease with the risk of metabolic syndrome and its components: a systematic review and meta-analysis

Chen, Tingqiao; Shao, Xinyi; Li, Hao; Chen, Yangmei; Liu, Lin; Zhong, Judan; Chen, Jin

doi:10.1007/s10238-023-01044-x

Cited by 3 publications

(1 citation statement)

References 48 publications

(111 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some studies have shown that patients with BD are more likely to have metabolic syndrome (MetS), which is reported to be present in 25.52% of patients [ 110 ]. Consistent with previous reports, a study by Chen et al confirmed an important association between BD and MetS: the risk of metabolic syndrome was 126% greater in the BD group than in the healthy control group [ 111 ]. These findings revealed that BD is significantly associated with insulin resistance, diabetes mellitus, and hypertension [ 111 ].…”

Section: Obesity and Eye Diseasessupporting

confidence: 89%

Obesity, body fat distribution and eye diseases

Bosello,

Vanzo,

Zaffalon

et al. 2024

Eat Weight Disord

View full text Add to dashboard Cite

Background The prevalence of obesity, a chronic disease, is increasing, and obesity is now considered a global epidemic. Eye diseases are also increasing worldwide and have serious repercussions on quality of life as well as increasingly high costs for the community. The relationships between obesity and ocular pathologies are not yet well clarified and are not pathologically homogeneous: they seem to be somehow linked to excess body fat, especially to the distribution of adipose tissue and its ectopic deposits. Purpose Our objective was to examine the associations between obesity and anthropometric indices, including body mass index (BMI), waist circumference (WC), and the waist/hip ratio (WHR), and the risk of most widespread eye diseases, with particular attention given to the most significant metabolic mechanisms. Methods This article provides a narrative overview of the effect of obesity and anthropometric measurements of body fat on prevalent eye diseases. We used the MEDLINE/PubMed, CINAHL, EMBASE, and Cochrane Library databases from 1984 to 2024. In addition, we hand-searched references from the retrieved articles and explored a number of related websites. A total of 153 publications were considered. Results There is significant evidence that obesity is associated with several eye diseases. Waist circumference (WC) and the waist/hip ratio (WHR) have been observed to have stronger positive associations with eye diseases than BMI. Conclusions Obesity must be considered a significant risk factor for eye diseases; hence, a multidisciplinary and multidimensional approach to treating obesity, which also affects ocular health, is important. In the prevention and treatment of eye diseases related to obesity, lifestyle factors, especially diet and physical activity, as well as weight changes, both weight loss and weight gain, should not be overlooked. Level of evidence Level V narrative review.

show abstract

Section: Obesity and Eye Diseasessupporting

confidence: 89%

Obesity, body fat distribution and eye diseases

Bosello,

Vanzo,

Zaffalon

et al. 2024

Eat Weight Disord

View full text Add to dashboard Cite

show abstract

Diabetes mellitus in rheumatic diseases: clinical characteristics and treatment considerations

Fedorchenko,

Mahmudov,

Abenov

et al. 2023

Rheumatol Int

View full text Add to dashboard Cite

The risk of cardiovascular comorbidity in children with Behçet’s disease

Demir,

Duzova,

Karagoz

et al. 2023

Rheumatology

View full text Add to dashboard Cite

Objective Patients with Behçet’s disease (BD) may experience long-term morbidity caused by various forms of cardiovascular disease. This study aimed to assess the risk for cardiovascular comorbidity in paediatric BD patients with and without vascular involvement, independent of the contribution of traditional risk factors. Methods Paediatric patients classified as having BD according to the 2015 Peadiatric BD (PEDBD) criteria were included in the study. Twenty-four-hour ambulatory blood pressure monitoring (ABPM), transthoracic echocardiography, and carotid intima-media thickness (cIMT) measurements were performed. Patients with an active disease or those who have other known risk factors for cardiovascular disease were not included in the study. Results Thirty-one children and adolescents with paediatric BD (16 female, 51.6%; F/M: 1.06) were enrolled in the study. Among the BD patients, 10 patients (34.4%) had abnormal ABPM. Carotid IMT values, mean arterial pressure, systolic and diastolic blood pressure by ABPM and the prevalence of abnormal ABPM, non-dipping, and ambulatory hypertension were similar between patients with and without vascular involvement. The echocardiography measurements showed that BD patients with vascular involvement had a significantly higher velocity and velocity time integral of the left ventricle outflow tract, which may indicate increased stiffness of the aorta. Conclusion Paediatric BD patients with vascular involvement may tend to have more cardiovascular risk factors. However, cardiovascular assessment should be considered in all BD patients, regardless of the involved systems. We suggest that ABPM may accurately define hypertension and cardiovascular risk in BD.

show abstract

Association of Behçet’s disease with the risk of metabolic syndrome and its components: a systematic review and meta-analysis

Cited by 3 publications

References 48 publications

Obesity, body fat distribution and eye diseases

Obesity, body fat distribution and eye diseases

Diabetes mellitus in rheumatic diseases: clinical characteristics and treatment considerations

The risk of cardiovascular comorbidity in children with Behçet’s disease

Contact Info

Product

Resources

About