Association of ATG16L1 and ATG5 gene polymorphisms with susceptibility to hepatitis B virus infection and progression to HCC in central China
Qiaoyu Wu,
Yaoling Ouyang
Abstract:Hepatitis B virus (HBV) infection is a severe public health problem worldwide. The relationship between polymorphisms of autophagy‐related 16‐like 1 gene (ATG16L1) and autophagy‐related gene 5 (ATG5) with susceptibility to the stage of HBV infection has been reported in different populations. Nevertheless, this association is not seen in the population of central China. This study recruited 452 participants, including 246 HBV‐infected patients (139 chronically infected HBV without hepatocellular carcinoma [HCC… Show more
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