Association of age-related eye diseases with cognitive frailty in older adults: a population-based study

Ghanbarnia, Mohammad Javad; Hosseini, Seyed Reza; Ghasemi, Mehrnoosh; Roustaei, Gholam Abbas; Mekaniki, Ebrahim; Ghadimi, Reza; Bijani, Ali; Rasoulinejad, Seyed Ahmad

doi:10.1007/s40520-023-02458-z

Cited by 5 publications

(2 citation statements)

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“…Evidently, findings from a certain population cannot be necessarily extrapolated to a different population due to the inherent geographic and ethnic differences of various populations. Previously, we conducted a study investigating the association between eye diseases and cognitive frailty in Iranian older adults [ 22 ]. To the best of our knowledge, there hasn’t been any other study regarding cognitive frailty in Iran.…”

Section: Introductionmentioning

confidence: 99%

“…As a result, various studies have investigated the risk factors of cognitive frailty to further our knowledge on the etiology of this condition. Cross-sectional studies have demonstrated an array of factors significantly associated with cognitive frailty including age, education level, depression, social support and social interactions, physical activity, nutrition, disability or even eye diseases such as cataract [18][19][20][21][22]. However, the literature hasn't been totally consistent regarding these risk factors and further research is required to corroborate these findings.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of cognitive frailty and its associated factors in a population of Iranian older adults

Ghanbarnia,

Hosseini,

Ahangar

et al. 2024

Aging Clin Exp Res

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Background In recent years cognitive frailty has emerged as an important predictor of adverse health outcomes in older adults. Herein, we aimed to investigate the prevalence and associated factors of cognitive frailty in a population of community-dwelling older adults in Iran. Method This cross-sectional study was conducted as part of the second cycle of the Amirkola Health and Aging Project (AHAP). Physical frailty and cognitive impairment were evaluated using the FRAIL questionnaire and the mini-mental state examination (MMSE) respectively. Cognitive frailty was defined as co-existence of frailty and cognitive impairment without presence of dementia. Depression and disability were assessed using the Persian version of geriatric depression scale (GDS) and instrumental activities of daily living (IADL) questionnaire. Results Overall 1775 individuals (47.1% female) with mean age of 69.7 ± 7.3 years were included in the final analysis. The prevalence of cognitive frailty was 12.0%. The prevalence of cognitive frailty among males and females was 4.3% and 20.7%, respectively. After adjusting for all possible confounders through binary logistic regression analysis, factors such as older age (OR 1.06, CI 1.03–1.09), female gender (OR 2.25, CI 1.42–3.57), illiteracy (OR 3.84, CI 2.03–8.29), more comorbidities (OR 1.21, CI 1.12–1.31), depression (OR 2.01, CI 1.40–2.86), and greater IADL disability (OR 1.68, CI 1.44–3.96), were independently and significantly associated with cognitive frailty. Conclusion In this population of Iranian older adults, prevalence of cognitive frailty was consistent with its estimated mean global prevalence. Age, gender, illiteracy, comorbidities, depression and IADL disability were associated with cognitive frailty. Further research is required to develop screening tools and prevention strategies.

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Section: Introductionmentioning

confidence: 99%