Association of adjuvant radiation and survival in human papilloma virus‐positive oropharynx squamous cell carcinoma with lymphovascular invasion as the sole adverse pathologic feature
Scott A. Hong,
Austin T. Armstrong,
Katherine Snow
et al.
Abstract:BackgroundPostoperative radiotherapy radiation therapy (PORT) for early‐stage human papillomavirus (HPV)‐positive oropharyngeal squamous cell carcinoma (OPSCC) with positive lymphovascular invasion (LVI) has an unclear association with overall survival (OS).MethodsThis retrospective cohort study queried the National Cancer Database for surgically treated, T1‐2, N0‐1 HPV+ OPSCC from 2010 to 2019. Primary exposures were LVI and PORT, and the main outcome was 5‐year OS. Odds ratios and hazard ratios (HR) with 95%… Show more
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