Association Between Urothelial Carcinoma After Renal Transplantation and Infection by Human Papillomavirus Types 16 and 18

Xiao, Jing; Zhu, Xiaoyan; Hao, Gangyue; Zhu, Yichen; Ma, Linlin; Zhang, Y.H.; Tian, Ye

doi:10.1016/j.transproceed.2011.03.053

Cited by 11 publications

(2 citation statements)

References 15 publications

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“…Recent studies suggested that direct DNA damage by immunosuppression is important in ESRD patients. The association between UC and viral infection, however, remains a controversial topic ( 6 , 7 ). On the other hand, drug-induced immunosuppression following renal transplant, and chronic bladder irritation due to anuria in ESRD patients, which decreases the effect of urinary tract washing by urine flow, have been reported to be predisposing factors for UC development ( 4 ).…”

Section: Discussionmentioning

confidence: 99%

Metachronous urothelial carcinoma of whole urinary tract in a dialysis-dependent patient: A case report

2016

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Numerous studies have reported an association between end-stage renal disease (ESRD) and malignancy. The predominant malignant tumor that occurs in patients with ESRD in Asian countries is urothelial carcinoma (UC). According to recent research, cases of UC in dialysis-dependent patients are associated with higher recurrence rates and more aggressive biological behavior compared with patients without ESRD. The necessity of 1-step total urinary tract exenteration for dialysis-dependent patients with UC is advocated by certain studies. The current study reports a case of metachronous bladder cancer and bilateral upper urinary tract tumor in a dialysis-dependent patient. Three separate surgeries were performed to remove the bladder, and left and right urinary tract, respectively. The question of whether the stepwise strategy or the 1-step surgery should be selected for such special cases remains in debate.

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Section: Discussionmentioning

confidence: 99%

Metachronous urothelial carcinoma of whole urinary tract in a dialysis-dependent patient: A case report

2016

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“…TCC did not show an increased incidence in HIV population, so this finding could suggest that immunodeficiency would not be the leading and solitary cause for pathogenesis in this subgroup of neoplasms. Regarding the TCC, two main viruses had been related with an increased risk developing this neoplasm: BK virus (BKV) [6] and human papillomavirus (HPV) types 16 and 18 [7]. …”

Section: Introductionmentioning

confidence: 99%

Transitional Cell Carcinoma of the Kidney Graft: An Extremely Uncommon Presentation of Tumor in Renal Transplant Recipients

Hevia

Gómez

Álvarez

et al. 2013

Case Reports in Transplantation

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Purpose. Transitional cell carcinoma (TCC) affecting the graft after renal transplantation is a very infrequent way of presentation of this tumor. Our aim is to present our single institution experience with 2 cases, as well as to perform a review of the literature about this tumor after the transplant. Materials and Methods. TCC of the graft developed in 2 of 1365 patients from 1977 to 2010, both cases in women. Data were analyzed for incidence, clinical presentation, treatment, and outcomes. Results. Both cases occurred in 2 mid-age women and resulted to be high grade and locally advanced TCCs, representing an incidence of 0,14% (2/1365). Clinical presentation was urinary obstruction for the first case and incidental ultrasound finding for the second. Preoperative staging was made with CT, cytology, pyelography, ureterorenoscopy, and biopsy. Treatment performed was nephroureterectomy of the graft with bladder cuff and regional lymphadenectomy. Pathological examination showed in both cases a locally advanced and high grade urothelial carcinoma of the pelvis allograft. After 24 and 14 months of followup, both patients are disease free. Conclusions. TCC of the kidney graft is an infrequent tumor that has only been reported in a few cases in the literature. It usually appears at a lower age, more often locally advanced, and with poor differentiation. A multidisciplinary approach to treatment should be required in these cases.

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Systematic review on oncologic outcomes on adjuvant endovesical treatment for non-muscle invasive bladder cancer in patients with solid organ transplant

et al. 2022

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Association Between Urothelial Carcinoma After Renal Transplantation and Infection by Human Papillomavirus Types 16 and 18

Cited by 11 publications

References 15 publications

Metachronous urothelial carcinoma of whole urinary tract in a dialysis-dependent patient: A case report

Metachronous urothelial carcinoma of whole urinary tract in a dialysis-dependent patient: A case report

Transitional Cell Carcinoma of the Kidney Graft: An Extremely Uncommon Presentation of Tumor in Renal Transplant Recipients

Systematic review on oncologic outcomes on adjuvant endovesical treatment for non-muscle invasive bladder cancer in patients with solid organ transplant

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