Association between urine cotinine levels, continuous performance test variables, and attention deficit hyperactivity disorder and learning disability symptoms in school-aged children

Cho, S.-C.; Hong, Yun Chul; Kim, J.-W.; Park, S.; Park, M.-H.; Hur, Ji-Won; Park, E.-J.; Hong, Soon Man; Lee, J.-H.; Shin, Min Sup; Kim, B.-N.; Yoo, Hee Jeong; Cho, I.-H.; Bhang, Soo-Young; Han, Seong-Jae

doi:10.1017/s0033291712001109

Cited by 26 publications

(23 citation statements)

References 42 publications

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“…The detailed protocol of the study was previously described elsewhere (Cho et al 2013; Hong et al 2013). Briefly, participants were recruited from five South Korean administrative regions (i.e., two urban cities, two industrial cities, and one rural district).…”

Section: Methodsmentioning

confidence: 99%

“…Blood concentrations of mercury (Rhee et al 2013) and manganese (Kim Y et al 2009) as well as creatinine-standardized urinary concentrations of cotinine (Cho et al 2010b, 2013), phthalate metabolites (mono- n -butyl phthalate, MnBP; mono-2-ethyl-5-oxohexyl phthalate, MEOHP; mono-2-ethylhexyl phthalate, MEHP) (Cho et al 2010a; Kim BN et al 2009) and BPA (Hong et al 2013) were also measured and included as covariates in the analysis.…”

Section: Methodsmentioning

confidence: 99%

“…Last, we further controlled for log 10 -transformed concentrations of mercury, manganese, cotinine, phthalate metabolites, and BPA, in addition to the covariates described above. The confounding variables were selected based on known predictors of neurodevelopment and previous publications (Cho et al 2013; Hong et al 2013; Kim BN et al 2009; Nigg et al 2010). We performed complete case analyses to address missing data for model covariates.…”

Section: Methodsmentioning

confidence: 99%

“…Another important issue is potential confounding by other environmental exposures such as mercury, manganese, phthalate metabolites, and bisphenol A (BPA), as well as cotinine (a biomarker for tobacco exposure), each of which may be associated with ADHD (Bouchard et al 2007; Braun et al 2009; Cheuk and Wong 2006; Cho et al 2010b, 2013; Hong et al 2013; Julvez et al 2010; Kim BN et al 2009). Few studies have accounted for multiple environmental risk factors in the same population (Goodlad et al 2013).…”

Section: Introductionmentioning

confidence: 99%

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Environmental Lead Exposure and Attention Deficit/Hyperactivity Disorder Symptom Domains in a Community Sample of South Korean School-Age Children

Hong

Kim

et al. 2015

Environ Health Perspect

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BackgroundLow-level environmental exposure to lead has been associated with both reduced intelligence and symptoms of attention deficit/hyperactivity disorder (ADHD). However, few studies have estimated the association of lead and intelligence independent of ADHD, and it is not clear from previous studies whether lead is associated with both inattention and impulsivity ADHD symptoms.ObjectivesWe estimated mutually adjusted associations of environmental lead exposure with both intelligence and ADHD symptoms, and associations between lead and specific ADHD-related domains.MethodsBlood lead concentrations were measured in a general population of 1,001 children 8–11 years of age. We used multivariable linear regression models to estimate associations of blood lead concentrations with IQ scores, teacher and parent ratings of ADHD symptoms, and measures of inattention and impulsivity. Models were adjusted for demographic variables and other environmental exposures (blood levels of mercury and manganese, urinary concentrations of cotinine, phthalate metabolites, and bisphenol A).ResultsAssociations of blood lead with lower IQ and higher impulsivity were robust to adjustment for a variety of covariates. When adjusted for demographic characteristics, other environmental exposures, and ADHD symptoms or IQ, a 10-fold increase in blood lead concentration was associated with lower Full-Scale IQ (–7.23; 95% CI: –13.39, –1.07) and higher parent- and teacher-rated hyperactivity/impulsivity scores (ADHD Rating Scale, 1.99; 95% CI: 0.17, 3.81 and 3.66; 95% CI: 1.18, 6.13, respectively) and commission errors (Continuous Performance Test, 12.27; 95% CI: –0.08, 24.62). Blood lead was not significantly associated with inattention in adjusted models.ConclusionsLow-level lead exposure was adversely associated with intelligence in school-age children independent of ADHD, and environmental lead exposure was selectively associated with impulsivity among the clinical features of ADHD.CitationHong SB, Im MH, Kim JW, Park EJ, Shin MS, Kim BN, Yoo HJ, Cho IH, Bhang SY, Hong YC, Cho SC. 2015. Environmental lead exposure and attention deficit/hyperactivity disorder symptom domains in a community sample of South Korean school-age children. Environ Health Perspect 123:271–276; http://dx.doi.org/10.1289/ehp.1307420

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Environmental Lead Exposure and Attention Deficit/Hyperactivity Disorder Symptom Domains in a Community Sample of South Korean School-Age Children

Hong

Kim

et al. 2015

Environ Health Perspect

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“…휴대전화 중독은 충 동성과 상관관계가 있고, 휴대전화 중독 청소년에서 충 동성이 높은 것으로 나타났다 [19]. 이와 같이 충동성은 자기통제가 결여된 상태 [20]로 청소년에서 충동성을 통 제하지 못하면 문제행동이 발생한다 [21]. 충동성은 조 절을 통해 중독을 예방 할 수 있기 때문에 [22] …”

Section: 휴대전화 중독은 휴대전화를 사용하지 않으면 불안unclassified

Effects of Self Esteem, Impulsive Behavior and Mental Health on Cellular Phone Addiction of Adolescents

Lee¹

2014

The Journal of the Korea Contents Association

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Purpose: The purpose of this study was done to investigate the relationship between self esteem, impulsive behavior and mental health among adolescents who were cellular phone addiction and those who were not. Methods: The data were collected using questionnaire from the sample of 239 middle school students. The data were collected from April 8 to 19, 2013. Data were analyzed using frequencies, means, χ 2 -test, Fisher's exact test, t-test and logistic regression analysis with SPSS 20.0. Results: Firstly, Significant differences were found for grade, sex, period, buying motives, the number of the messages/day, use, phone bill, callers between students who were cellular phone addiction and those who were not. Secondly, Self esteem for the cellular phone addiction were lower than for those in the non-addiction group, and impulsive behavior and mental health were higher. Thirdly, The logistic regression analysis revealed that self esteem, non-planning impulsiveness, mental health total, grade, sex, period, and the number of the messages/day significantly associated with being a cellular phone addiction. Conclusions: The result of this study offer basic data for the development of intervention programs to prevent adolescents cellular phone addiction.

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Exploration of a somatosensory interactive assessment tool for children with intellectual disabilities

Lu,

Li,

Zeng

2024

PsyCh Journal

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Based on the functional assessment concept and embodied assessment requirements, the present study aimed to design and develop an assessment tool for children with intellectual disabilities with the help of somatosensory interactive (SI) technology. The sample in this study consisted of 73 children with intellectual disabilities and 70 children with typical development. Data were collected through three SI tasks, four traditional executive function tasks, and user experience interviews to analyse the effectiveness of the SI assessment tool. The results showed that the SI assessment tool had good scale validity, discriminant validity, and the ability to identify intellectual disabilities. Children preferred SI tasks and showed higher involvement and more positive emotions. The SI tool with three SI tasks is a more scientific, effective, and advanced tool for assessing children with intellectual disabilities.

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Association between urine cotinine levels, continuous performance test variables, and attention deficit hyperactivity disorder and learning disability symptoms in school-aged children

Abstract: Our data indicate that environmental exposure to tobacco smoke is associated with ADHD and learning disabilities in children, and that impairments in attention and inhibitory control probably mediate the effect.

Cited by 26 publications

References 42 publications

Environmental Lead Exposure and Attention Deficit/Hyperactivity Disorder Symptom Domains in a Community Sample of South Korean School-Age Children

Environmental Lead Exposure and Attention Deficit/Hyperactivity Disorder Symptom Domains in a Community Sample of South Korean School-Age Children

Effects of Self Esteem, Impulsive Behavior and Mental Health on Cellular Phone Addiction of Adolescents

Exploration of a somatosensory interactive assessment tool for children with intellectual disabilities

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