Association between Triglyceride glucose index in type 2 diabetes mellitus patients and acute ischemic stroke

Abstract

Background: The stroke is a leading cause of mortality and disability globally. Diabetes mellitus increases the risk of stroke. It was observed that the risk of stroke is usually higher among the young diabetic patients. It was evident that pre-diabetic patients have a great risk of stroke as the presence of glucose in blood results in vascular endothelial dysfunction, increased early-age arterial stiffness, systemic inflammation and thickening of the capillary basal membrane.In this study we aimed to determine the association between Triglyceride Glucose Index in Type-2 diabetes mellitus patients and acute ischemic stroke. 
 Methods: The present prospective observational study was undertaken to elucidate the association between Triglyceride glucose index in type 2 diabetes mellitus patients and acute ischemic stroke.A total of 75 patients with acute ischemic stroke and had history of diabetes mellitus during the period of study were included in the study.
 Results: In our study the mean age of the patients was 58.74±11.37 years and the majority of the patients were males (57%) followed by 43% females. The average NIHSS score of study participants was 5. The mean FPG value was as 6.13±2.03 (mmol/l), mean TC was 5.76±1.4 (mmol/l), mean TG 1.98±0.93 was (mmol/l) and mean TyG index was 8.76±0.28.
 Conclusion: The present study concluded that the TyG index is an important risk factor of ischemic stroke as it was observed that the patients with higher TyG index has higher incidence of ischemic stroke.