Association between time from cessation of oxytocin infusion for labor to delivery and intraoperative severe blood loss during cesarean section: a retrospective cohort study

Shinohara, Satoshi; Okuda, Yasuhiko; Hirata, Shuji; Suzuki, Kohta

doi:10.1080/14767058.2018.1521798

“…Compared with conventional anesthesia, epidural anesthesia with a higher maternal acceptance enjoys a rosy analgesic effect, which is widely used in clinical practice. is kind of anesthesia method is to inject local anesthetics into the epidural space of parturients, which aims to block the spinal nerve root and produce temporary analgesic anesthesia effect in the nearby area, so as to bring down the stress response of parturients [19][20][21]. In addition, the parturients will be in a relatively conscious state to feel the contractions in the whole process of labor.…”

Section: Discussionmentioning

confidence: 99%

The Effectiveness and Safety of Ropivacaine and Medium-Dose Dexmedetomidine in Cesarean Section

Huang

¹

,

Niu

²

2022

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

Objective: To study the effects of epidural anesthesia with different doses of dexmedetomidine and ropivacaine on postoperative hemodynamics and neonatal outcome of cesarean section parturients. Methods. A total of 90 parturients who underwent cesarean section admitted to our hospital from January 2019 to January 2020 were selected as the research objects and were divided into groups A, B, and C according to different dosages of dexmedetomidine, with 30 cases in each group. Groups A, B, and C were given dexmedetomidine 0.5 μg/kg, 0.8 μg/kg, 1.0 μg/kg, respectively, combined with 0.2% ropivacaine. The anesthesia effect, traction response, hemodynamic indexes, and neonatal Apgar score of the three groups were compared; the “Numerical Rating Scale (NRS) Score” was used to assess the postoperative pain of the parturients, and the “Ramsay Sedation Scale” was used to assess the sedation state of the parturients. Results. The superior anesthesia effect of group B was obtained compared with groups A and C ( P < 0.05 ). Group B witnessed a lower degree of grade III stretching response, as compared to group A ( P < 0.05 ). In comparison with groups A and C, superior results of the heart rate and mean artery pressure (MAP) of group B at T1 and T2 were obtained ( P < 0.05 ). The neonatal Apgar score in group B was lower than those in groups A and C ( P < 0.05 ), and the NRS score of group B was also lower than that of group A ( P < 0.05 ). Compared with groups A and C, group B yielded a more favorable outcome in terms of the Ramsay score ( P < 0.05 ). Conclusion. The use of medium-dose dexmedetomidine in cesarean section parturients is safer and can effectively reduce the impact on maternal hemodynamics, which is worthy of promotion and application.

show abstract

“…If the pre-pregnancy BMI was �25.0 kg/m 2 , excessive weight gain was defined as weight gain of 7 kg or more throughout the pregnancy [15]. Macrosomia was defined as a birth weight �3,500 g [20].…”

Section: Data Collectionmentioning

confidence: 99%

Fetal biparietal diameter as a potential risk factor for prolonged second stage of labor: A retrospective observational cohort study

Shinohara

¹

,

Amemiya

²

,

Takizawa

³

et al. 2020

PLoS ONE

Self Cite

1

0

View full text Add to dashboard Cite

Prolonged second stage of labor is a common abnormality of labor progression. Very little research exists regarding the relationship between prolonged second stage of labor and antepartum sonographic fetal head biometry parameters, especially fetal biparietal diameter (BPD). Fetal BPD assessment is essential for estimating fetal weight, and these measurements are readily available to Japanese obstetricians. We conducted a retrospective observational cohort study to evaluate the association between BPD fetal Z-score and prolonged second stage of labor in a Japanese cohort. Individual BPD data measured using a GE Voluson 730 expert ultrasound system (GE, Healthcare Japan, Tokyo, Japan) were converted to Z-scores for a particular gestational age. After excluding patients with multiple pregnancies and emergency or elective cesarean sections, a total of 2,711 (nulliparity, n = 1341) Japanese women who delivered at term were included. We analyzed the incidence of prolonged second stage of labor and the association between BPD Z-score measured <7 days before delivery and prolonged second stage of labor by parity. The overall incidence of prolonged second stage of labor was 18.3% (246/1,341) in nulliparous women and 4.6% (63/1,370) in multiparous women. In nulliparous women, multivariable analysis indicated that BPD Z-score was significantly associated with prolonged second stage of labor (adjusted odds ratio, 1.18; 95% confidence interval, 1.02-1.37). Kaplan-Meier survival analysis showed that at each time point during the second stage of labor, the percentage of women who had not yet delivered was higher among those who delivered neonates with large BPD Z-scores than among those who delivered neonates with smaller BPD Z-scores. On the contrary, in multiparous women, BPD Z-score was not statistically associated with prolonged second stage of labor. Our results suggest that considering BPD Z-score is helpful in the management of nulliparous women who are at risk of developing a prolonged second stage of labor.

show abstract

Cohort Study Summary of the Effects of Carboprost Tromethamine Combined with Oxytocin on Infant Outcome, Postpartum Hemorrhage and Uterine Involution of Parturients Undergoing Cesarean Section

Gong¹,

Wu²

2022

Computational and Mathematical Methods in Medicine

View full text Add to dashboard Cite

Background. Carboprost tromethamine injection has a high safety factor in clinical application and has a good effect on uterine smooth muscle and vasoconstriction. Carboprost aminobutyriol combined with oxytocin may be beneficial to infant outcome and uterine involution after cesarean section. Objective. To investigate the effects of carboprost tromethamine combined with oxytocin on infant outcome, postpartum hemorrhage, and uterine involution in parturients undergoing cesarean section. Methods. A total of 120 parturients undergone cesarean section in our hospital from February 2019 to April 2021 were selected as the object of study. The parturients were randomly divided into control group ( n = 60 ) and research group ( n = 60 ). The control group was treated with oxytocin, and the research group was treated with carboprost aminobutyriol combined with oxytocin. The amount of maternal bleeding, uterine floor decline index, the end of lochia, poor rate of uterine involution, infant outcome, and the incidence of adverse drug reactions were compared between the two groups. Results. The amount of bleeding in the research group was significantly lower than that in the control group ( P < 0.05 ). The position of the last uterine floor and the index of uterine floor downward movement in the research group were significantly higher than those in the control group ( P < 0.05 ). The disappearance time of bloody lochia and serous lochia in the research group was significantly shorter than that in the control group ( P < 0.05 ). The end time of lochia in the research group was higher than that in the control group, and the rate of uterine involution in the research group was lower than that in the control group ( P < 0.05 ). The neonatal weight and Apgar score in the research group were higher than those in the control group, and the hospitalization rate of neonatal ICU in the research group was significantly lower than that in the control group. The incidence of adverse reactions in the research group was significantly lower than that in the control group ( P < 0.05 ). Conclusion. Carboprost aminobutyriol combined with carbestatin can effectively prevent the occurrence of bleeding after cesarean section, improve uterine involution, and improve neonatal birth quality, which is worth popularizing.

show abstract

Association between time from cessation of oxytocin infusion for labor to delivery and intraoperative severe blood loss during cesarean section: a retrospective cohort study

Abstract: Consideration of RT is helpful in the management of women undergoing cesarean section after oxytocin pretreatment.

Cited by 3 publications

References 24 publications

The Effectiveness and Safety of Ropivacaine and Medium-Dose Dexmedetomidine in Cesarean Section

The Effectiveness and Safety of Ropivacaine and Medium-Dose Dexmedetomidine in Cesarean Section

Fetal biparietal diameter as a potential risk factor for prolonged second stage of labor: A retrospective observational cohort study

Cohort Study Summary of the Effects of Carboprost Tromethamine Combined with Oxytocin on Infant Outcome, Postpartum Hemorrhage and Uterine Involution of Parturients Undergoing Cesarean Section

Contact Info

Product

Resources

About