Association between the risk of malnutrition and functional capacity in patients with peripheral arterial disease: A cross-sectional study

Abstract

Introduction The risk of malnutrition is an important predictor of functional capacity in the elderly population. However, whether malnutrition is associated with functional capacity in patients with peripheral artery disease (PAD) is poorly known. Purpose To analyse the association between the risk of malnutrition and functional capacity in patients with PAD. Methods This cross-sectional study included 135 patients with PAD of both genders, ≥50 years old, with symptomatic PAD (Rutherford stage I to III) in one or both limbs and with ankle-brachial index ≤0.90. The risk of malnutrition was assessed by the short form of the Mini Nutritional Assessment-Short Form and patients were classified as having normal nutritional status (n = 92) and at risk of malnutrition (n = 43). Functional capacity was objectively assessed using the six-minute walking test (6MWT, absolute maximal distance and relativized and expressed as a percentage of health subjects), short-physical performance battery (SPPB, balance, gait speed and the sit and stand test) and the handgrip test, and subjectively, using the Walking Impairment Questionnaire and Walking Estimated-Limitation Calculated by History. The association between the risk of malnutrition and functional capacity was analysed using bivariate and multivariate logistic regression adjustments for gender, age, ankle-brachial index, body mass index, use of statins, coronary arterial disease and stroke. For all statistical analyses, significance was accepted at p<0.05. Results Thirty-two per cent of our patients were classified with a risk of malnutrition. The risk of malnutrition was associated with the absolute 6MWT total distance (OR = 0.994, P = 0.031) relative 6MWT total distance (OR = 0.971, P = 0.038), lowest SPPB total score (OR = 0.682, P = 0.011), sit and stand (OR = 1.173, P = 0.003) and usual 4-meter walk test (OR = 1.757, P = 0.034). Conclusion In patients with PAD, the risk of malnutrition was associated with objective measurements of functional capacity.

Compreendendo a existência da Doença Arterial Periférica no Brasil: revisão sistemática

“…Contudo, nas condições da doença arterial periférica, a presença de placas ateroscleróticas nas artérias periféricas compromete essa entrega eficiente 6,8 .…”

“…O tratamento da Doença Arterial Periférica não se restringe apenas à gestão dos sintomas locais, mas deve ser abordado como parte integrante do cuidado cardiovascular global, visando reduzir o risco de complicações mais graves e melhorar a saúde vascular de maneira holística 6 .…”

Revisional surgery for malnutrition after SADI-S: prevalence, indications, techniques and outcomes

“…Hypertension and poor control of diabetes, defined by HbA1c above 7% or high glycemia are both related to atherosclerosis, which along with age could be the cause of an impaired intestinal absorption and a decreased adaption capacity of the small bowel. Although there are no studies on microvascularization of the small bowel and nutrition, atherosclerosis has been previously related to malnutrition in patients with peripheral arterial disease [13].…”

Revisional surgery for malnutrition after SADI-S: Prevalence, Indications, Techniques and Outcomes. Single Center Experience.

“…Hypertension and poor control of diabetes, defined by HbA1c above 7% or high glycemia are both related to atherosclerosis, which along with age could be the cause of an impaired intestinal absorption and a decreased adaption capacity of the small bowel. Although there are no studies on microvascularization of the small bowel and nutrition, atherosclerosis has been previously related to malnutrition in patients with peripheral arterial disease (10).…”